摘要:
The present invention relates to a non-human transgenic animal whose genome comprises a stably integrated transgenic nucleotide sequence encoding Lysine-specific Demethylase 1 (LSD1) operably linked to a promoter. The invention further concerns methods for generating the non-human animal and its use as a cancer model.
摘要:
An electrically active electrode element for an implantable electrode lead, having an electrode, which includes an electrically active electrode surface facing toward the outside, and an elongated electric feed line, which is capable of establishing an electric connection to an electrically active implant at the proximal end thereof, and which is embodied as an electrically conducting cable end-to-end, wherein the cable forms the electrode at the distal end thereof. A related electrode lead having such an electrode element is provided, and a method for the production of said electrode line utilizing the electrode element is also provided.
摘要:
A group of sealants are described which utilize a by-product of paint booth spray operations. Processed paint booth overspray particles are combined with various resins, curing agents to form the sealant compositions.
摘要:
An insulating tube for an electrode lead for medical use, particularly a cardiac pacemaker electrode lead, defibrillator electrode lead, electrode lead for nerve stimulation or the like, including a base material made of at least one material of the group consisting of silicones, polyurethanes, polyimide, PTFE, ETFE, and copolymers made of silicones and polyurethanes. In order to improve the functionality of such an insulating tube during friction of the tube with friction partners, at least in one volume region, which preferably forms the lateral surface of the insulating tube, the tube, in addition to the base material, includes a fibrous and/or particulate filler material having a higher abrasion resistance than the respective base material. A corresponding electrode lead is also provided, and a simple and cost-effective method for producing such an insulating tube and such an electrode lead.
摘要:
A composition which cures and foams at room temperature contains a acid-catalyzed, polymerizable resin, an acid and a filler which liberates gas in an endothermic reaction with the acid. The acid serves the dual purpose of catalyzing the polymerization reaction and generating the foaming gas.
摘要:
The invention relates to a connecting piece for connecting to an electrode line and to an electric implant, whereby the connecting piece has an electrically conducting plug module, multiple ring-shaped electrically conducting contacts with insulation sections having the same outside diameter arranged in the longitudinal direction therebetween, multiple electric connecting lines, and a supporting element which supports the insulation sections and secures them in the radial direction. A through-bore situated within the supporting element receives the plug module and/or a feeder line of an electrode body. The supporting element has grooves spaced along the longitudinal direction, and recesses extending from the proximal end to the distal end and running parallel to the longitudinal axis wherein the electric connecting lines are fit.
摘要:
A terminal part for an electrode line for connection to an implantable heart stimulator, the terminal part having multiple annular, electrically conductive contacts of equal external diameter having insulation sections of the same external diameter situated between them in the longitudinal direction, of which the electrically conductive contacts are each electrically connected to an electrically conductive terminal line, the terminal part being formed by multiple insulating adapters and by electrical contacts held thereby having terminal lines fastened thereon, which are plugged together and connected using a thermoplastic injection molding compound after being plugged together, the terminal part otherwise being implemented in such a way that it is to be connected as an independent unit to a remaining electrode line.
摘要:
A method of aligning the bonding head of a bonder, in particular a die bonder, or of a pick and place machine comprising the steps of a) placing an alignment plate provided with two plane parallel surfaces on a supporting surface which is set plane parallel to the bonding surface upon which the semiconductor chip will be bonded to the carrier material; b) calibration of a measuring device, the signal of which is dependent upon the position of the alignment plate; c) grasping the alignment plate with the bonding head of the bonder and holding the alignment plate free at a slight distance above the measuring device; and d) alignment of the bonding head until the signal from the measuring device is equal to the signal following step b).
摘要:
A device, including an implantable electronic circuit integrated at least one of in or on a substrate, wherein the device includes a hermetic enclosure having a space therein, wherein the substrate forms at least a portion of the hermetic enclosure.
摘要:
The invention relates to a connecting piece for connecting to an electrode line and to an electric implant, whereby the connecting piece has an electrically conducting plug module, multiple ring-shaped electrically conducting contacts with insulation sections having the same outside diameter arranged in the longitudinal direction therebetween, multiple electric connecting lines, and a supporting element which supports the insulation sections and secures them in the radial direction. A through-bore situated within the supporting element receives the plug module and/or a feeder line of an electrode body. The supporting element has grooves spaced along the longitudinal direction, and recesses extending from the proximal end to the distal end and running parallel to the longitudinal axis wherein the electric connecting lines are fit.