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    Two-stage scar generation for treating atrial fibrillation
    7.
    发明申请
    Two-stage scar generation for treating atrial fibrillation 审中-公开
    用于治疗房颤的两阶段瘢痕形成

    公开(公告)号：US20060116666A1

    公开(公告)日：2006-06-01

    申请号：US11246412

    申请日：2005-10-07

    Applicant: Richard Cornelius ,  William Swanson ,  Daniel Sullivan ,  Ronald Shebuski

    Inventor： Richard Cornelius ,  William Swanson ,  Daniel Sullivan ,  Ronald Shebuski

    IPC: A61B17/00 ,  A61B18/18

    CPC classification number: A61B17/08 ,  A61B17/12 ,  A61B18/14 ,  A61B2017/00243 ,  A61B2017/081 ,  A61B2018/00375

    Abstract: The present invention seeks to provide an implant configured to utilize at least two different scar-generating mechanisms that are generated in sequential or overlapping stages. For example, in one embodiment the present invention provides an expandable device that can be positioned at a desired target location within a patient to generate mechanical ablation damage. After a predetermined amount of mechanical ablation has occurred, additional ablation damage is generated by a different source, such as energy delivery, drug delivery, or inflammatory material delivery. In this respect, the overall ablation scarring can be better controlled by utilizing the ablation techniques that are most appropriate at specific phases of a technique or locations within a patient.

    Abstract translation: 本发明寻求提供一种被配置为利用在连续或重叠阶段中产生的至少两种不同的瘢痕产生机制的植入物。 例如，在一个实施例中，本发明提供了一种可扩张装置，其可以定位在患者内的期望的目标位置以产生机械消融损伤。 在发生预定量的机械消融之后，通过不同的来源产生额外的消融损伤，例如能量递送，药物递送或炎性物质递送。 在这方面，可以通过利用在技术的特定阶段或患者内的位置最适合的消融技术来更好地控制整体消融瘢痕形成。

    Methods and devices for creating electrical block at specific sites in cardiac tissue with targeted tissue ablation
    8.
    发明授权
    Methods and devices for creating electrical block at specific sites in cardiac tissue with targeted tissue ablation 失效
    用于在靶组织消融的心脏组织的特定部位产生电阻的方法和装置

    公开(公告)号：US07266414B2

    公开(公告)日：2007-09-04

    申请号：US10971452

    申请日：2004-10-22

    Applicant: Richard Cornelius ,  William Swanson

    Inventor： Richard Cornelius ,  William Swanson

    IPC: A61B18/18 ,  A61N1/00

    CPC classification number: A61B18/1477 ,  A61B18/1492 ,  A61B2018/00214 ,  A61B2018/00898

    Abstract: In one embodiment, the present invention provides a bipolar ablation device with multiple needle electrodes that penetrate a desired target tissue. These electrodes may be arranged in a variety of therapeutically effective arrangements, such as a comb-like shape, a multi-needle wheel, or an expanding bow design. By contacting and preferably penetrating the cardiac tissue with bipolar electrodes, a user can more precisely create ablation-induced scarring and thus electrical block at desired target locations without causing unwanted damage and related complications.

    Abstract translation: 在一个实施例中，本发明提供一种双极消融装置，其具有穿透期望的目标组织的多个针电极。 这些电极可以以各种治疗有效的布置布置，例如梳状形状，多针轮或扩张弓形设计。 通过接触并优选用双极电极穿透心脏组织，使用者可以更准确地产生消融引起的瘢痕形成并因此在期望的目标位置电阻塞，而不会引起不必要的损伤和相关并发症。

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