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公开(公告)号：US20210290828A1
公开(公告)日：2021-09-23
申请号：US12298287
申请日：2007-05-08
Applicant: Zhihao Yang , Richard Cornelius , Paige Hastings , Bodo Quint , Gerd Seibold , Ib Erling Joergensen , Stevan Nielsen
Inventor： Zhihao Yang , Richard Cornelius , Paige Hastings , Bodo Quint , Gerd Seibold , Ib Erling Joergensen , Stevan Nielsen
Abstract: The present invention generally relates to the use of small particles, such as micro particles or nanoparticles, to produce a therapeutic scar such as “trans-mural” scarring or other desired “deep tissue” scarring. In one preferred embodiment, these particles can be delivered to a target location by an implant. More specifically, these particles can be incorporated into the structure of implants or into the coatings on implants. In another preferred embodiment, these small particles can be delivered directly with a catheter by electrophoresis or hydraulic pressure.
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公开(公告)号：US08840658B2
公开(公告)日：2014-09-23
申请号：US12396329
申请日：2009-03-02
Applicant: William Swanson , Richard Cornelius , Robert S. Schwartz
Inventor： William Swanson , Richard Cornelius , Robert S. Schwartz
IPC: A61F2/86
CPC classification number: A61F2/2487 , A61B17/320725 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2002/8483 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/9511 , A61F2002/9665 , A61F2220/0016 , A61F2230/0054
Abstract: The present invention provides an electrical block implant sized and shaped for securement at the perimeter of the pulmonary ostium of the left atrium. By utilizing various expandable ring designs and optional anchoring mechanisms, the present invention causes even, circular scarring around the perimeter of the pulmonary ostium, achieving reliable blocking of aberrant electrical signals responsible for atrial fibrillation.
Abstract translation: 本发明提供了一种电动块植入物，其大小和形状用于在左心房的肺口周边固定。 通过利用各种可膨胀环设计和可选的锚固机构，本发明在肺口周围产生均匀的圆形瘢痕，实现了负责心房颤动的异常电信号的可靠阻断。
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公开(公告)号：US08409268B2
公开(公告)日：2013-04-02
申请号：US12699749
申请日：2010-02-03
Applicant: William Swanson , Richard Cornelius , Robert S. Schwartz
Inventor： William Swanson , Richard Cornelius , Robert S. Schwartz
IPC: A61F2/84
CPC classification number: A61F2/2487 , A61B17/320725 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2002/8483 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/9511 , A61F2002/9665 , A61F2220/0016 , A61F2230/0054
Abstract: The present invention provides an electrical block implant sized and shaped for securement at the perimeter of the pulmonary ostium of the left atrium. By utilizing various expandable ring designs and optional anchoring mechanisms, the present invention causes even, circular scarring around the perimeter of the pulmonary ostium, achieving reliable blocking of aberrant electrical signals responsible for atrial fibrillation.
Abstract translation: 本发明提供了一种电动块植入物，其大小和形状用于在左心房的肺口周边固定。 通过利用各种可膨胀环设计和可选的锚固机构，本发明在肺口周围产生均匀的圆形瘢痕，实现了负责心房颤动的异常电信号的可靠阻断。
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公开(公告)号：US20100163054A1
公开(公告)日：2010-07-01
申请号：US12532131
申请日：2008-03-18
Applicant: Michael Breznel , Paul Hindrichs , Richard Cornelius
Inventor： Michael Breznel , Paul Hindrichs , Richard Cornelius
CPC classification number: A61F6/225 , A61B17/11 , A61B17/12022 , A61B17/12031 , A61B17/12045 , A61B17/12099 , A61B17/12168 , A61B17/12172 , A61B2017/12127 , A61B2017/4233 , A61F6/20 , A61F6/202
Abstract: The invention describes methods and apparatus for creating permanent occlusion of body lumens such as the fallopian tubes. The methods and apparatus use non-surgical approaches to deliver permanent implants which create acute occlusion of desired body lumens which resolve to permanent occlusions of the lumens.
Abstract translation: 本发明描述了用于产生体腔（例如输卵管）的永久性闭塞的方法和装置。 所述方法和装置使用非手术方法来递送永久性植入物，其产生期望体腔的急性闭塞，其解决为腔内的永久性闭塞。
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公开(公告)号：US20090171445A1
公开(公告)日：2009-07-02
申请号：US12396329
申请日：2009-03-02
Applicant: William Swanson , Richard Cornelius , Robert S. Schwartz
Inventor： William Swanson , Richard Cornelius , Robert S. Schwartz
IPC: A61F2/06
CPC classification number: A61F2/2487 , A61B17/320725 , A61F2/848 , A61F2/91 , A61F2/915 , A61F2002/8483 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/9511 , A61F2002/9665 , A61F2220/0016 , A61F2230/0054
Abstract: The present invention provides an electrical block implant sized and shaped for securement at the perimeter of the pulmonary ostium of the left atrium. By utilizing various expandable ring designs and optional anchoring mechanisms, the present invention causes even, circular scarring around the perimeter of the pulmonary ostium, achieving reliable blocking of aberrant electrical signals responsible for atrial fibrillation.
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Patent Agency Ranking
公开(公告)号：US20060178725A1
公开(公告)日：2006-08-10
申请号：US11333966
申请日：2006-01-17
Applicant: Richard Cornelius
Inventor： Richard Cornelius
IPC: A61F2/06
CPC classification number: A61F2/915 , A61F2/91 , A61F2002/065 , A61F2002/821 , A61F2002/91525 , A61F2002/91533 , A61F2002/9511 , A61F2220/0016 , A61F2230/0013
Abstract: The present invention provides an electrical block implant sized and shaped for securement at the perimeter of the pulmonary ostium of the left atrium. By utilizing various expandable ring designs and optional anchoring mechanisms, the present invention causes even, circular scarring around the perimeter of the pulmonary ostium, achieving reliable blocking of aberrant electrical signals responsible for atrial fibrillation.
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公开(公告)号：US20060161146A1
公开(公告)日：2006-07-20
申请号：US11337618
申请日：2006-01-23
Applicant: Richard Cornelius , William Swanson
Inventor： Richard Cornelius , William Swanson
IPC: A61B18/18
CPC classification number: A61B18/1492 , A61B18/02 , A61B18/1477 , A61B18/18 , A61B90/11 , A61B90/39 , A61B2017/00247 , A61B2017/00867 , A61B2017/22038 , A61B2017/3484 , A61B2017/3486 , A61B2018/0016 , A61B2018/00214 , A61B2018/00267 , A61B2018/00279 , A61B2018/00285 , A61B2018/00345 , A61B2018/00375 , A61B2018/00392 , A61B2018/00404 , A61B2018/00839 , A61B2018/00898 , A61B2018/1425 , A61B2018/144 , A61B2018/1475 , A61M25/0068 , A61M25/0074 , A61M25/0082 , A61M25/04 , A61M25/0662 , A61N7/02 , C08L2201/12
Abstract: The present invention provides positioning mechanisms for devices that cause conduction blocks or ablation in desired areas of tissue. The positioning mechanisms allow for variable geometry of the target sites and enable more accurate therapy at the tissue site.
Abstract translation: 本发明提供了用于在组织的期望区域中引起传导阻滞或消融的装置的定位机构。 定位机制允许目标部位的可变几何形状，并使得能够在组织部位进行更准确的治疗。
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公开(公告)号：US20060116666A1
公开(公告)日：2006-06-01
申请号：US11246412
申请日：2005-10-07
Applicant: Richard Cornelius , William Swanson , Daniel Sullivan , Ronald Shebuski
Inventor： Richard Cornelius , William Swanson , Daniel Sullivan , Ronald Shebuski
CPC classification number: A61B17/08 , A61B17/12 , A61B18/14 , A61B2017/00243 , A61B2017/081 , A61B2018/00375
Abstract: The present invention seeks to provide an implant configured to utilize at least two different scar-generating mechanisms that are generated in sequential or overlapping stages. For example, in one embodiment the present invention provides an expandable device that can be positioned at a desired target location within a patient to generate mechanical ablation damage. After a predetermined amount of mechanical ablation has occurred, additional ablation damage is generated by a different source, such as energy delivery, drug delivery, or inflammatory material delivery. In this respect, the overall ablation scarring can be better controlled by utilizing the ablation techniques that are most appropriate at specific phases of a technique or locations within a patient.
Abstract translation: 本发明寻求提供一种被配置为利用在连续或重叠阶段中产生的至少两种不同的瘢痕产生机制的植入物。 例如，在一个实施例中，本发明提供了一种可扩张装置，其可以定位在患者内的期望的目标位置以产生机械消融损伤。 在发生预定量的机械消融之后，通过不同的来源产生额外的消融损伤，例如能量递送，药物递送或炎性物质递送。 在这方面，可以通过利用在技术的特定阶段或患者内的位置最适合的消融技术来更好地控制整体消融瘢痕形成。
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公开(公告)号：US2588702A
公开(公告)日：1952-03-11
申请号：US15602650
申请日：1950-04-14
Applicant: RICHARD CORNELIUS JAMES
Inventor： RICHARD CORNELIUS JAMES
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公开(公告)号：US2443228A
公开(公告)日：1948-06-15
申请号：US50533843
申请日：1943-10-07
Applicant: RICHARD CORNELIUS JAMES
Inventor： RICHARD CORNELIUS JAMES
IPC: F16H61/02
CPC classification number: F16H61/0274 , F16H2708/24 , F16H2710/00 , Y10T74/19251 , Y10T74/1926 , Y10T74/19274
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