公开(公告)号：US20230131044A1

公开(公告)日：2023-04-27

申请号：US18083947

申请日：2022-12-19

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Noriyuki HATSUGAI ,  Yasuaki OKUMURA ,  Fumiya WAYAMA

IPC: C25B3/25 ,  C07K1/113

Abstract: A method for cleaving a disulfide bond in a protein includes: cleaving a disulfide bond in a protein present in a reaction system by reduction via a reduced redox protein; and reducing an oxidized redox protein produced by oxidation of the reduced redox protein in the cleaving to the reduced redox protein by donating an electron from an electrode connected to an external power supply outside the reaction system to the oxidized redox protein.

公开(公告)号：US20230117095A1

公开(公告)日：2023-04-20

申请号：US18082785

申请日：2022-12-16

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Fumiya WAYAMA ,  Noriyuki HATSUGAI ,  Yasuaki OKUMURA

IPC: G01N27/416

Abstract: A target molecule redox method includes: a first process of bringing a liquid containing a target molecule to a non-flowing state, and causing electron transfer between an electron carrier immobilized on an electrode connected to an external power supply outside the liquid and the target molecule to oxidize or reduce the target molecule; and a second process of bringing the liquid to a flowing state. The first process and the second process are sequentially repeated.

公开(公告)号：US20150164393A1

公开(公告)日：2015-06-18

申请号：US14631095

申请日：2015-02-25

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Tatsurou KAWAMURA ,  Yasuaki OKUMURA ,  Masaru MINAMIGUCHI ,  Masahiko SHIOI

IPC: A61B5/145 ,  A61B5/1455

CPC classification number: A61B5/14532 ,  A61B5/1451 ,  A61B5/1455 ,  G01N21/64 ,  G01N21/658

Abstract: An exemplary apparatus for measuring the concentration of a test substance in an organism disclosed herein includes: a measurement system which measures first and second concentrations that are concentrations of the test substance at positions A and B, respectively, where the positions A and B are located inside of the organism but outside of the blood vessel of the organism, and the position B is located more distant from the blood vessel than the position A is; and a decision circuit which determines, based on the first and second concentrations, whether or not an equilibrium has been established yet between a concentration of the test substance inside of the blood vessel and a concentration of the test substance measured at a position inside of the organism but outside of the blood vessel of the organism.

Abstract translation: 用于测量本文公开的生物体中的测试物质的浓度的示例性装置包括：测量系统，其分别测量第一和第二浓度，其分别是位置A和B位于位置A和B处的测试物质的浓度 在生物体的内部，但在生物体的血管之外，位置B位于比位置A更远离血管的位置; 以及判定电路，其基于第一和第二浓度确定在血管内的被检物质的浓度与在该血管内的位置处测定的被检物质的浓度之间是否已经建立平衡 有机体，但在生物体的血管之外。

公开(公告)号：US20230119996A1

公开(公告)日：2023-04-20

申请号：US18084957

申请日：2022-12-20

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Noriyuki HATSUGAI ,  Yasuaki OKUMURA ,  Fumiya WAYAMA

IPC: C07K1/113 ,  C12N9/02 ,  C12N11/14

Abstract: An allergen inactivation method includes an inactivation step of inactivating an allergen present in a reaction system by reduction via a reduced redox protein, and a reduction process of reducing an oxidized redox protein produced by oxidation of the reduced redox protein in the inactivating to the reduced redox protein by donating an electron from an electrode connected to an external power supply outside the reaction system to the oxidized redox protein.

公开(公告)号：US20240226633A9

公开(公告)日：2024-07-11

申请号：US18538086

申请日：2023-12-13

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Fumiya WAYAMA ,  Noriyuki HATSUGAI ,  Yasuaki OKUMURA

IPC: A62D3/115 ,  A62D3/02 ,  A62D3/37 ,  C12Q1/00

CPC classification number: A62D3/115 ,  A62D3/02 ,  A62D3/37 ,  C12Q1/001 ,  A62D2101/26

Abstract: An immobilized enzyme electrode includes: an electrode; a redox enzyme that oxidizes or reduces a target molecule; and an electron carrier that performs electron transport between the electrode and the redox enzyme. The electron carrier is immobilized on the electrode via a first linker that is in a form of a chain, and the redox enzyme is immobilized on the electrode via a second linker that is longer than the first linker, the second linker being in a form of a chain.

公开(公告)号：US20240131378A1

公开(公告)日：2024-04-25

申请号：US18538086

申请日：2023-12-13

Applicant: Panasonic Intellectual Property Management Co., Ltd.

Inventor： Fumiya WAYAMA ,  Noriyuki HATSUGAI ,  Yasuaki OKUMURA

IPC: A62D3/115 ,  A62D3/02 ,  A62D3/37 ,  C12Q1/00

CPC classification number: A62D3/115 ,  A62D3/02 ,  A62D3/37 ,  C12Q1/001 ,  A62D2101/26

Abstract: An immobilized enzyme electrode includes: an electrode; a redox enzyme that oxidizes or reduces a target molecule; and an electron carrier that performs electron transport between the electrode and the redox enzyme. The electron carrier is immobilized on the electrode via a first linker that is in a form of a chain, and the redox enzyme is immobilized on the electrode via a second linker that is longer than the first linker, the second linker being in a form of a chain.

公开(公告)号：US20240117325A1

公开(公告)日：2024-04-11

申请号：US18390220

申请日：2023-12-20

Applicant: Panasonic Intellectual Property Management Co, Ltd.

Inventor： Noriyuki Hatsugai ,  Fumiya WAYAMA ,  Yasuaki OKUMURA

IPC: C12N9/02 ,  C07K14/47 ,  C07K17/00

CPC classification number: C12N9/0051 ,  C07K14/47 ,  C07K17/00 ,  C07K2319/00 ,  C12Y108/07002

Abstract: A fusion protein obtained by fusing a ferredoxin-thioredoxin reductase and thioredoxin via a linker peptide. The linker peptide includes glycine (G) and serine (S).

公开(公告)号：US20160066953A1

公开(公告)日：2016-03-10

申请号：US14941007

申请日：2015-11-13

Applicant: PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD.

Inventor： Masaru MINAMIGUCHI ,  Yasuaki OKUMURA ,  Tatsurou KAWAMURA ,  Takahiro AOKI ,  Masahiko SHIOI

IPC: A61B17/34 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B17/3468 ,  A61B5/14546 ,  A61B5/14556 ,  A61B5/1459 ,  A61B5/6849 ,  A61B5/686 ,  G01N21/645 ,  G01N21/65 ,  G01N21/658 ,  G01N2021/6417

Abstract: A sensor embedding device according to the present disclosure is a sensor embedding device which embeds a sensor in a subject, the sensor having a sensing region in which to detect a state of the subject, including: a needle to be inserted in the subject, the needle having a hole; a sensor retainer to retain the sensor so that the sensor is ready to be embedded inside the subject in such a manner that the sensing region is oriented in a predetermined direction; and a movable section to move the sensor into the subject with a slide of the sensor retainer inside the hole.

Abstract translation: 根据本公开的传感器嵌入装置是将传感器嵌入到对象中的传感器嵌入装置，所述传感器具有检测对象的状态的感测区域，包括：插入对象的针， 针孔有孔; 传感器保持器，用于保持传感器，使得传感器准备好以使得感测区域沿预定方向定向的方式嵌入在对象内; 以及可移动部分，用于将传感器保持器滑入孔内，将传感器移动到被检体内。