公开(公告)号：US20190387963A1

公开(公告)日：2019-12-26

申请号：US16561816

申请日：2019-09-05

Applicant: OLYMPUS CORPORATION

Inventor： Keigo MATSUO ,  Hisashi ODE ,  Toshiro OKAMURA ,  Atsushi DOI ,  Satoshi WATANABE

IPC: A61B1/05 ,  A61B1/06 ,  A61B1/00

Abstract: A lens system is configured to form an image of an object on an imaging surface of an image sensor. A branching optical system is configured such that an image-forming light flux in the lens system is split and propagated into a plurality of optical paths having different optical path lengths and such that the principal rays of a plurality of image-forming light fluxes obtained after the splitting are incident on a predetermined region of the image sensor.

公开(公告)号：US20220074854A1

公开(公告)日：2022-03-10

申请号：US17528404

申请日：2021-11-17

Applicant: OLYMPUS CORPORATION

Inventor： Yoshimasa SUZUKI ,  Toshiro OKAMURA

IPC: G01N21/41 ,  G02B21/08

Abstract: A refractive index distribution estimating system includes an illumination optical system configured to illuminate a sample, an imaging optical system configured to form an optical sample image, an image sensor configured to capture optical images of the sample, and a processor configured to reconstruct a refractive index distribution of the sample from images. The processor performs processing including the steps of: estimating the sample; calculating the estimated sample image from a plurality of first wavefronts emanating from a plurality of modeled light sources; optimizing a refractive index distribution of the estimated sample from a plurality of second wavefronts after the first wavefronts pass through the estimated sample, the captured image, and the image of the estimated sample; updating the estimation sample by repeating calculation of the estimated sample image and optimization of the refractive index distribution of the estimated sample; and reconstructing and outputting a structure of the estimated sample.

公开(公告)号：US20140037288A1

公开(公告)日：2014-02-06

申请号：US14015377

申请日：2013-08-30

Applicant: OLYMPUS CORPORATION

Inventor： Koji MATSUMOTO ,  Toshiro OKAMURA ,  Satoshi WATANABE ,  Takeshi YAMAZAKI

IPC: H04J14/02

CPC classification number: H04J14/02 ,  G02B6/3504

Abstract: An optical unit for a wavelength-selecting switch according to the present invention comprises: an input port; a dispersion section that produces wavelength dispersion of input light that is input from the input port; a light-collecting element that collects the light dispersed by the dispersion section; an output port; an optical path correction section that shifts the light that is dispersed by the dispersion section; an adjustment section that changes the amount of shift produced by the optical path correction section; and a casing that hermetically seals the input port, dispersion section, light-collecting element, output port, and optical path correction section. The casing has an optically transparent section in a location onto which the light that is collected by the light-collecting element is directed. The adjustment section is arranged outside the casing. The optical path correction section can be controlled from outside the casing by the adjustment section.

Abstract translation: 根据本发明的用于波长选择开关的光学单元包括：输入端口; 产生从输入端口输入的输入光的波长色散的色散部分; 收集由分散部分散的光的聚光元件; 输出端口 光路校正部，其使由所述分散部分散射的光移动; 调整部，其改变由光路校正部产生的偏移量; 以及气密地密封输入端口，分散部分，集光元件，输出端口和光路校正部分的壳体。 壳体在由聚光元件收集的光被引导到的位置上具有光学透明部分。 调节部配置在壳体的外部。 可以通过调节部从外壳的外部控制光路校正部。

公开(公告)号：US20190121290A1

公开(公告)日：2019-04-25

申请号：US16224530

申请日：2018-12-18

Applicant: OLYMPUS CORPORATION

Inventor： Toshiro OKAMURA

IPC: G03H1/04 ,  G03H1/08

Abstract: An illumination unit emits illumination light to a specimen held by a sample holder, which includes an AF mark that changes at least the amplitude or phase of part of the illumination light. An image sensor includes multiple pixels two-dimensionally arranged on an imaging surface, captures an image of the intensity distribution of an interference pattern formed on the imaging surface, and outputs captured image data. An AF operation unit generates a first intensity distribution representing a measurement value of the interference pattern corresponding to the AF mark based on the captured image data, generates a second intensity distribution representing a calculation value of an interference pattern corresponding to the AF mark by calculation, and executes an autofocus operation wherein the first intensity distribution approaches the second. A reconstruction calculation unit reconstructs a subject image representing the specimen based on the captured image data.

公开(公告)号：US20180292637A1

公开(公告)日：2018-10-11

申请号：US16007070

申请日：2018-06-13

Applicant: OLYMPUS CORPORATION

Inventor： Toshiro OKAMURA

IPC: G02B21/16 ,  G02B21/06 ,  G02B21/36 ,  G01N21/64

CPC classification number: G02B21/16 ,  G01N21/01 ,  G01N21/64 ,  G01N21/6458 ,  G01N2021/6463 ,  G02B6/0011 ,  G02B21/06 ,  G02B21/361 ,  G02B21/365

Abstract: An illumination device irradiates a sample with excitation light spatially modulated according to a two-dimensional pattern while temporally varying the pattern. A plate-shaped first optical member has a light receiving face that faces the sample face, receives fluorescence light emitted from the sample via the light receiving face, and guides the fluorescence light in a direction that is in parallel with the light receiving face. A photodetector receives the fluorescence light guided by the first optical member, and outputs a detection signal. A fluorescence image of the sample is generated using the detection signal and an intensity distribution formed on the sample face due to the excitation light acquired for every pattern.