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    Water Treatment Systems, Devices, and Methods for Fluid Preparation
    2.
    发明公开
    Water Treatment Systems, Devices, and Methods for Fluid Preparation 审中-公开

    公开(公告)号：US20240091423A1

    公开(公告)日：2024-03-21

    申请号：US18522304

    申请日：2023-11-29

    Applicant: NxStage Medical, Inc.

    Inventor： Goetz FRIEDERICHS ,  Dennis M. TREU ,  Jeffrey H. BURBANK ,  Yuriy N. TATASHIN

    IPC: A61M1/16 ,  C02F1/28 ,  C02F1/42

    CPC classification number: A61M1/1656 ,  A61M1/1664 ,  A61M1/1666 ,  A61M1/1672 ,  C02F1/283 ,  C02F1/42 ,  C02F1/001

    Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.

    Pressure Measurement Devices, Methods, and Systems
    5.
    发明申请
    Pressure Measurement Devices, Methods, and Systems 审中-公开

    公开(公告)号：US20190277716A1

    公开(公告)日：2019-09-12

    申请号：US16420249

    申请日：2019-05-23

    Applicant: NxStage Medical, Inc.

    Inventor： James M. BRUGGER ,  Dennis M. TREU ,  Jeffrey H. BURBANK ,  Scott W. NEWELL ,  William J. SCHNELL ,  Kenneth E. BUCKLER

    IPC: G01L9/00 ,  G01L19/00 ,  A61M1/36

    Abstract: A pressure measurement pod for use in blood circuits includes a pressure sensing pod defining a chamber and having a rigid wall portion and an integral flexible wall portion forming a flexible, moveable, fluid-impermeable diaphragm with a first major side thereof facing an interior of the chamber and a second major side opposite the first major side. The second major side faces outwardly away from the chamber, and the pod has ports on sides of the chamber. The internal surfaces of the chamber and ports are shaped such that any contour following the internal surfaces to the outside of one of the ports traces only surfaces characterized by positive or neutral draft angles such that invasive mold portions may be withdrawn through the ports thereby permitting the pressure measurement pod to be molded in a single shot molding process.

    Filtration System for Preparation of Fluids for Medical Applications
    6.
    发明申请
    Filtration System for Preparation of Fluids for Medical Applications 审中-公开

    公开(公告)号：US20190275226A1

    公开(公告)日：2019-09-12

    申请号：US16423214

    申请日：2019-05-28

    Applicant: NxStage Medical, Inc.

    Inventor： Jeffrey H. BURBANK ,  Dennis M. TREU ,  Goetz FRIEDERICHS ,  Brian C. GREEN ,  Christopher S. MCDOWELL ,  James M. BRUGGER

    IPC: A61M1/16 ,  A61M1/14 ,  A61M1/28 ,  A61M1/34 ,  C02F1/44

    Abstract: A fluid preparation system has a sealed sterilized fluid circuit with a sealed sterilized container with a conductivity sensor in communication with an interior of said container. Further, at least one sealed connector is adapted for adding fluid to said container, and at least one sealed connector is adapted for removing fluid from said container. The conductivity sensor is contained in a test line in communication with said interior and is adapted to be connected to a source of suction thereby to draw a sample of contents of said container. Furthermore, the test line may have a check valve to prevent ingress of contaminants into said container, and the sealed connector is adapted for adding fluid to said container and may have an inline sterile filter. Furthermore, the system may have a controller that controls pumping actuators.

    Pinch Clamp Devices, Methods, and Systems
    8.
    发明申请
    Pinch Clamp Devices, Methods, and Systems 审中-公开

    公开(公告)号：US20190076642A1

    公开(公告)日：2019-03-14

    申请号：US16185589

    申请日：2018-11-09

    Applicant: NxStage Medical, Inc.

    Inventor： Scott W. NEWELL ,  Dennis M. TREU ,  Kenneth E. BUCKLER

    IPC: A61M39/28 ,  A61M39/10

    Abstract: A tube clamp closes a flexible tube by applying a pinching force to walls of the flexible tube. The clamp includes a housing connected to a circular flange, the circular flange including a tubular wall surrounding a central bore and including at least one slot in the tubular wall sized to accept the flexible tube. A pinching element is positioned inside the central bore and is rotatable about a central axis of the circular flange. The pinching element includes a pinching projection that has a cross-sectional shape bound by a partial circle, and the partial circle has a radius substantially same as an inner radius of the tubular wall.

    Peritoneal Dialysis Systems, Devices, and Methods
    10.
    发明申请
    Peritoneal Dialysis Systems, Devices, and Methods 审中-公开

    公开(公告)号：US20170203026A1

    公开(公告)日：2017-07-20

    申请号：US15476927

    申请日：2017-03-31

    Applicant: NxStage Medical, Inc.

    Inventor： Jeffrey H. BURBANK ,  James M. BRUGGER ,  Dennis M. TREU ,  Mark T. WYETH

    IPC: A61M1/28 ,  A61M1/16

    Abstract: A method of performing a dialysis treatment includes using a pump and a dialysate supply line to transport peritoneal dialysis fluid, the supply line having a proximal end into which peritoneal dialysis fluid is supplied and from which spend dialysate is withdrawn, and a distal end which is connected to a patient's peritoneal access. The method further includes generating proximal and distal pressure signals using pressure detectors located at both the proximal and distal ends, respectively, of said supply line. During a drain cycle in which spent dialysate is pumped from the patient, the method includes, responsively to the proximal and distal pressure signals, detecting a characteristic of a pressure difference between the distal and proximal ends whose magnitude is determined by a predicted change in dialysate properties, and responsively to the characteristic, generating a signal indicating the change in dialysate properties.

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