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公开(公告)号:US20190275254A1
公开(公告)日:2019-09-12
申请号:US16461045
申请日:2017-12-01
申请人: Novo Nordisk A/S
摘要: A drug delivery device comprising a housing, a piston rod, a transmission member, a helical torsion drive spring coupled to the transmission member and the housing, and a drive member in engagement with the piston rod and adapted to be rotated by the transmission member to thereby move the piston rod distally during expelling. The device further comprises dose setting means allowing a user to simultaneously set a dose and strain the drive spring correspondingly. The drive spring comprises a plurality of wire windings and is formed from a wire having a rectangular cross section wound on edge with the height larger than the thickness. The spring is operated such that the tilt angle for at least a portion of the rectangular wire will increase when the drive spring is strained from an initial strained state to a fully strained state, this resulting in a corresponding non-linear spring characteristic.
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公开(公告)号:US12115358B2
公开(公告)日:2024-10-15
申请号:US16981328
申请日:2019-03-22
申请人: Novo Nordisk A/S
CPC分类号: A61M5/31595 , A61M5/2033 , A61M5/31526 , A61M5/3202 , A61M2005/3126
摘要: A drug delivery device includes a dose counting mechanism and an end-of-content or remaining-dose indication. For example, a dose expelling mechanism is coupled to a reciprocating element configured to undergo a predefined motion during each dose expelling action to allow a dose to be expelled. The predefined motion includes displacement in a first axial direction from a first position to a second position followed by displacement in a second axial direction from the second position to the first position, with a counter element being movable in the first axial direction. First and second unidirectional ratchet mechanisms prevent motion in the first axial direction and allow motion in the second axial direction of the reciprocating element relative to the counter element, and vice versa, respectively.
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公开(公告)号:US20210178076A1
公开(公告)日:2021-06-17
申请号:US17269319
申请日:2019-08-26
申请人: Novo Nordisk A/S
摘要: A cartridge comprising a generally cylindrical cartridge main body with a proximal edge portion having a circumferential inner surface and a proximal opening surrounded by a circumferential edge, a piston slidable received therein, and a ring-formed code member attached to the circumferential edge portion and comprising an axially extending mounting portion in engagement with the edge portion circumferential inner surface, a flange portion having a distally facing mounting surface in engagement with the circumferential edge and a proximally facing stop surface, and a drive opening allowing a piston rod to engage the piston proximal surface, wherein the flange portion radially extends within the circumferential boundaries of the cartridge main body.
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公开(公告)号:US20210154406A1
公开(公告)日:2021-05-27
申请号:US16769068
申请日:2018-12-04
申请人: Novo Nordisk A/S
摘要: The present invention concerns a drug delivery device (1) comprising: a housing (2) extending along a main axis, a torsion spring (5) comprising a first spring end (4) arranged stationarily with respect to the housing (2) and a second spring end (6) capable of rotation about the main axis, a rotatable shaft (80) extending along the main axis, the rotatable shaft (80) having a non-self-locking thread (81) and being axially fixed with respect to the housing (2), a spring end retainer (82) to which the second spring end (6) is attached, the spring end retainer (82) being rotationally fixed relative to the rotatable shaft (80), and a nut member (45) engaged with the non-self-locking thread (81), the nut member (45) being axially movable by translation relative to the housing (2) to thereby travel the non-self-locking thread (81) between a first position in which the torsion spring (5) is in a relaxed state and a second position in which the torsion spring (5) is in a strained state.
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公开(公告)号:US20200368435A1
公开(公告)日:2020-11-26
申请号:US16765268
申请日:2018-11-20
申请人: Novo Nordisk A/S
摘要: The present invention provides a power unit (1) for a drug delivery device as well as methods for providing and mounting the power unit (1) in the drug delivery device. The power unit (1) comprises a first interface member (30) extending along a reference axis and comprising a hollow body (31) and a first engagement structure (35), a second interface member (10) comprising a tubular structure (11) extending at least partially through the hollow body (31) and having a skirt (12), and a second engagement structure (14) configured for releasable engagement with the first engagement structure (35), and a torsion spring (20) comprising a first end portion (23) being attached to the first interface member (30) and a second end portion (22) being attached to the second interface member (10), the torsion spring (20) being pre-strained to induce a relative rotational motion between the first interface member (30) and the second interface member (10). The first interface member (30) and the second interface member (10) are configured for relative motion along the reference axis from a first relative axial position in which the first engagement structure (35) and the second engagement structure (14) are engaged to prevent the relative rotational motion between the first interface member (30) and the second interface member (10) to a second relative axial position in which the first engagement structure (35) and the second engagement structure (14) are disengaged. In the first relative axial position of the first interface member (30) and the second interface member (10) the torsion spring (20) is accommodated in a user inaccessible space (39) defined by the hollow body (31) and the skirt (12).
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公开(公告)号:US11648351B2
公开(公告)日:2023-05-16
申请号:US16765268
申请日:2018-11-20
申请人: Novo Nordisk A/S
CPC分类号: A61M5/2033 , A61M5/31585 , A61M5/31593 , A61M5/348 , A61M5/31525 , A61M5/31533 , A61M5/31565 , A61M5/31576 , A61M2005/2013 , A61M2005/31588
摘要: The present invention provides a power unit (1) for a drug delivery device as well as methods for providing and mounting the power unit (1) in the drug delivery device. The power unit (1) comprises a first interface member (30) extending along a reference axis and comprising a hollow body (31) and a first engagement structure (35), a second interface member (10) comprising a tubular structure (11) extending at least partially through the hollow body (31) and having a skirt (12), and a second engagement structure (14) configured for releasable engagement with the first engagement structure (35), and a torsion spring (20) comprising a first end portion (23) being attached to the first interface member (30) and a second end portion (22) being attached to the second interface member (10), the torsion spring (20) being pre-strained to induce a relative rotational motion between the first interface member (30) and the second interface member (10). The first interface member (30) and the second interface member (10) are configured for relative motion along the reference axis from a first relative axial position in which the first engagement structure (35) and the second engagement structure (14) are engaged to prevent the relative rotational motion between the first interface member (30) and the second interface member (10) to a second relative axial position in which the first engagement structure (35) and the second engagement structure (14) are disengaged. In the first relative axial position of the first interface member (30) and the second interface member (10) the torsion spring (20) is accommodated in a user inaccessible space (39) defined by the hollow body (31) and the skirt (12).
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公开(公告)号:US11633540B2
公开(公告)日:2023-04-25
申请号:US16769068
申请日:2018-12-04
申请人: Novo Nordisk A/S
摘要: The present invention concerns a drug delivery device (1) comprising: a housing (2) extending along a main axis, a torsion spring (5) comprising a first spring end (4) arranged stationarily with respect to the housing (2) and a second spring end (6) capable of rotation about the main axis, a rotatable shaft (80) extending along the main axis, the rotatable shaft (80) having a non-self-locking thread (81) and being axially fixed with respect to the housing (2), a spring end retainer (82) to which the second spring end (6) is attached, the spring end retainer (82) being rotationally fixed relative to the rotatable shaft (80), and a nut member (45) engaged with the non-self-locking thread (81), the nut member (45) being axially movable by translation relative to the housing (2) to thereby travel the non-self-locking thread (81) between a first position in which the torsion spring (5) is in a relaxed state and a second position in which the torsion spring (5) is in a strained state.
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