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公开(公告)号：US20150011638A1
公开(公告)日：2015-01-08
申请号：US14463966
申请日：2014-08-20
发明人： Y. Joseph Mo , Qin Wang , James L. Yeager , Mingqi Lu
IPC分类号： A61K9/00 , A61K31/5575 , A61K47/14 , A61K47/26 , A61K47/18 , A61K47/10 , A61K31/167 , A61K47/36
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
摘要翻译： 提供了用于治疗早泄的组合物和方法，其中组合物包含局部麻醉剂，剪切稀化聚合物增稠剂，选自脂族C 1至C 8醇，脂族C 8至C 30酯的亲脂性组分 ，液体多元醇及其混合物，向组合物提供在约3至约7.4范围内提供缓冲pH值的水和缓冲系统施用于阴茎口。
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公开(公告)号：US09060929B2
公开(公告)日：2015-06-23
申请号：US14463959
申请日：2014-08-20
发明人： Y. Joseph Mo , Mingqi Lu , Qin Wang , James L. Yeager
IPC分类号： A61K31/5575 , A61K31/445 , A61K9/00 , A61K9/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/36 , A61P15/00 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/465 , A61K31/557 , A61K31/736 , A61K31/20 , A61K31/4453
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a vasoactive prostaglandin, a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
摘要翻译： 提供了用于治疗早泄的组合物和方法，其中组合物包含血管活性前列腺素，局部麻醉剂，剪切稀化聚合物增稠剂，亲脂性组分，其选自脂族C1至C8醇，脂族 C8至C30酯，液体多元醇及其混合物，向组合物提供约3至约7.4范围内缓冲的pH值的水和缓冲系统施用于阴茎。
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公开(公告)号：US20150011587A1
公开(公告)日：2015-01-08
申请号：US14463959
申请日：2014-08-20
发明人： Y. Joseph Mo , Mingqi Lu , Qin Wang , James L. Yeager
IPC分类号： A61K9/00 , A61K31/445 , A61K47/36 , A61K31/167 , A61K47/18 , A61K47/10 , A61K47/14 , A61K31/5575 , A61K47/26
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
摘要翻译： 提供了用于治疗早泄的组合物和方法，其中组合物包含局部麻醉剂，剪切稀化聚合物增稠剂，选自脂族C 1至C 8醇，脂族C 8至C 30酯的亲脂性组分 ，液体多元醇及其混合物，向组合物提供在约3至约7.4范围内提供缓冲pH值的水和缓冲系统施用于阴茎口。
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公开(公告)号：US11246932B2
公开(公告)日：2022-02-15
申请号：US15942156
申请日：2018-03-30
发明人： Tian Wen , Liu Liu , Mingqi Lu , Jieshan Bai , Y. Joseph Mo
摘要： Compositions and methods for the treatment of vasospasm are provided comprising applying an amount of a semi-solid vasoactive prostaglandin composition to the affected tissue. Also provided are methods of improving microcirculation in a replanted body part.
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公开(公告)号：US20150272875A1
公开(公告)日：2015-10-01
申请号：US14673847
申请日：2015-03-30
发明人： Y. Joseph Mo , Mingqi Lu , Qin Wang , James L. Yeager
IPC分类号： A61K9/00 , A61K47/18 , A61K31/445 , A61K31/167 , A61K31/4453 , A61K31/5575 , A61K45/06
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
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公开(公告)号：US09066854B2
公开(公告)日：2015-06-30
申请号：US14463921
申请日：2014-08-20
发明人： Mingqi Lu , Qin Wang , James L. Yeager , Y. Joseph Mo
IPC分类号： A61K31/5575 , A61K31/4453 , A61K9/00 , A61K9/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/36 , A61P15/00 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/445 , A61K31/465 , A61K31/557 , A61K31/736 , A61K31/20
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
摘要翻译： 提供了用于治疗早泄的组合物和方法，其中组合物包含局部麻醉剂，剪切稀化聚合物增稠剂，选自脂族C 1至C 8醇，脂族C 8至C 30酯的亲脂性组分 ，液体多元醇及其混合物，向组合物提供在约3至约7.4范围内提供缓冲pH值的水和缓冲系统施用于阴茎口。
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公开(公告)号：US09056044B2
公开(公告)日：2015-06-16
申请号：US14463966
申请日：2014-08-20
发明人： Y. Joseph Mo , Mingqi Lu , Qin Wang , James L. Yeager
IPC分类号： A61K31/5575 , A61K31/167 , A61K9/00 , A61K9/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/36 , A61P15/00 , A61K31/00 , A61K31/165 , A61K31/445 , A61K31/465 , A61K31/557 , A61K31/736 , A61K31/20 , A61K31/4453
CPC分类号： A61K9/0034 , A61K9/0014 , A61K31/00 , A61K31/165 , A61K31/167 , A61K31/20 , A61K31/445 , A61K31/4453 , A61K31/465 , A61K31/557 , A61K31/5575 , A61K31/736 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/18 , A61K47/26 , A61K47/32 , A61K47/36 , Y10S514/947 , A61K2300/00
摘要： Compositions and methods for the treatment of premature ejaculation are provided wherein a composition comprising a vasoactive prostaglandin, a topical anesthetic, a shear-thinning polymeric thickener, a lipophilic component that is selected from the group consisting of an aliphatic C1 to C8 alcohol, an aliphatic C8 to C30 ester, a liquid polyol and a mixture thereof, water and a buffer system that provides a buffered pH value for the composition in the range of about 3 to about 7.4 is administered to the penile meatus.
摘要翻译： 提供了用于治疗早泄的组合物和方法，其中组合物包含血管活性前列腺素，局部麻醉剂，剪切稀化聚合物增稠剂，亲脂性组分，其选自脂族C1至C8醇，脂族 C8至C30酯，液体多元醇及其混合物，向组合物提供约3至约7.4范围内缓冲的pH值的水和缓冲系统施用于阴茎。
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8.发明申请PROSTAGLANDIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF VASOSPASM 审中-公开PROSTAGLANDIN组合物和治疗VASOSPASM的方法公开(公告)号：US20140206766A1
公开(公告)日：2014-07-24
申请号：US14172591
申请日：2014-02-04
发明人： Tian Wen , Liu Liu , Mingqi Lu , Jieshan Bai , Y. Joseph Mo
IPC分类号： A61K47/18 , A61K31/5575
CPC分类号： A61K47/18 , A61K9/0014 , A61K31/5575 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/36
摘要： Compositions and methods for the treatment of vasospasm are provided comprising applying an amount of a semi-solid vasoactive prostaglandin composition to the affected tissue. Also provided are methods of improving microcirculation in a replanted body part.
摘要翻译： 提供了用于治疗血管痉挛的组合物和方法，包括将一定量的半固体血管活性前列腺素组合物施用于受影响的组织。 还提供了改善再植体部分中的微循环的方法。
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公开(公告)号：US20140142188A1
公开(公告)日：2014-05-22
申请号：US14154892
申请日：2014-01-14
发明人： Tian Wen , Liu Liu , Mingqi Lu , Jieshan Bai , Y. Joseph Mo
IPC分类号： A61K47/18 , A61K31/5575
CPC分类号： A61K47/18 , A61K9/0014 , A61K31/5575 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/36
摘要： Compositions and methods for the treatment of vasospasm are provided comprising applying an amount of a semi-solid vasoactive prostaglandin composition to the affected tissue. Also provided are methods of improving microcirculation in a replanted body part.
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