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    Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent
    1.
    发明授权
    Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent 有权
    使用至少一种（二氢）茉莉酸衍生物作为脱屑剂

    公开(公告)号：US07365097B2

    公开(公告)日：2008-04-29

    申请号：US10899398

    申请日：2004-07-27

    申请人： Michel Neuwels ,  Maria Dalko

    发明人： Michel Neuwels ,  Maria Dalko

    IPC分类号： A01N37/08 ,  A01N37/10 ,  A01N37/00 ,  A61K8/18

    CPC分类号： C07C59/13 ,  C07C2601/08

    摘要： Disclosed herein is the cosmetic use, as a desquamating agent, of at least one (dihydro)jasmonic acid derivative of a given formula.Further disclosed herein is a cosmetic method for smoothing the visible and/or tactile irregularities of the skin surface, for example, for smoothing wrinkles and fine lines and/or skin spots and/or smoothing the skin, comprising topically applying, to the skin, a composition comprising, in a physiologically acceptable medium, at least one (dihydro)jasmonic acid derivative and glycerine.Other embodiments disclosed herein are novel (dihydro)jasmonic acid derivatives.

    摘要翻译： 本文公开了具有给定式的至少一种（二氢）茉莉酸衍生物作为脱屑剂的美容用途。 本文进一步公开的是用于平滑皮肤表面的可见和/或触觉不规则性的化妆方法，例如用于平滑皱纹和细纹和/或皮肤斑点和/或使皮肤光滑，包括局部施用于皮肤， 在生理学上可接受的介质中包含至少一种（二氢）茉莉酸衍生物和甘油的组合物。 本文公开的其它实施方案是新的（二氢）茉莉酸衍生物。

    Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent
    2.
    发明申请
    Use of at least one (dihydro)jasmonic acid derivative as a desquamating agent 有权
    使用至少一种（二氢）茉莉酸衍生物作为脱屑剂

    公开(公告)号：US20050063999A1

    公开(公告)日：2005-03-24

    申请号：US10899398

    申请日：2004-07-27

    申请人： Michel Neuwels ,  Maria Dalko

    发明人： Michel Neuwels ,  Maria Dalko

    IPC分类号： C07C59/13 ,  A61K7/00

    CPC分类号： C07C59/13 ,  C07C2601/08

    摘要： Disclosed herein is the cosmetic use, as a desquamating agent, of at least one (dihydro)jasmonic acid derivative of a given formula. Further disclosed herein is a cosmetic method for smoothing the visible and/or tactile irregularities of the skin surface, for example, for smoothing wrinkles and fine lines and/or skin spots and/or smoothing the skin, comprising topically applying, to the skin, a composition comprising, in a physiologically acceptable medium, at least one (dihydro)jasmonic acid derivative and glycerine. Other embodiments disclosed herein are novel (dihydro)jasmonic acid derivatives.

    摘要翻译： 本文公开了具有给定式的至少一种（二氢）茉莉酸衍生物作为脱屑剂的美容用途。 本文进一步公开的是用于平滑皮肤表面的可见和/或触觉不规则性的化妆方法，例如用于平滑皱纹和细纹和/或皮肤斑点和/或使皮肤光滑，包括局部施用于皮肤， 在生理学上可接受的介质中包含至少一种（二氢）茉莉酸衍生物和甘油的组合物。 本文公开的其它实施方案是新的（二氢）茉莉酸衍生物。

    Compositions comprising jasmonic acid derivatives and use of these derivatives
    5.
    发明授权
    Compositions comprising jasmonic acid derivatives and use of these derivatives 有权
    包含茉莉酸衍生物的组合物和这些衍生物的用途

    公开(公告)号：US08603502B2

    公开(公告)日：2013-12-10

    申请号：US10356551

    申请日：2003-02-03

    申请人： Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    发明人： Christophe Boulle ,  Maria Dalko ,  Jean-Luc Leveque ,  Lucie Simonetti

    IPC分类号： A61K31/557

    CPC分类号： C07C69/732 ,  A61K8/345 ,  A61K8/365 ,  A61K8/44 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08 ,  C07C35/06 ,  C07C59/11 ,  C07C59/46 ,  C07C69/675 ,  C07C2601/08

    摘要： Cosmetic or pharmaceutical compositions comprising compounds of formula (I) and the corresponding salts thereof: wherein: R1 is a radical chosen from —COOR′, —CONR′R″, —CH2OR′, —COR′, —CH2R′, —SO2OR′, —PO3R′R″ and —NHR′, wherein R′ and R″, which may be identical or different, are defined herein; R2 is chosen from saturated and unsaturated, linear, branched and cyclic hydrocarbon radicals comprising from 1 to 18 carbon atoms which are optionally substituted by from 1 to 5 identical or different entities chosen from —OR′″, —OCOR′″, —SR′″, —SCOR′″, NR′″R″″, —NHCOR′″, halogen, —CN, —COOR′″ and —COR′″, wherein R′″ and R″″, which may be identical or different, are defined herein, as well as the use of these compounds, for example, to promote skin desquamation, to stimulate epidermal renewal and/or to combat the signs of skin ageing.

    摘要翻译： 包含式（I）化合物及其相应盐的化妆品或药物组合物：其中：R1为选自-COOR'，-CONR'R“，-CHOOR'，-COR'，-CH2R'，-SO2OR的基团 '，-PO 3 R'R“和-NHR'，其中R'和R”可以相同或不同，在本文中定义; R 2选自包含1至18个碳原子的饱和和不饱和的，直链的，支链的和环状的烃基，其任选被1-5个相同或不同的选自-OR“，-OCOR” - ， - SR“'，-SCOR''，NR”'R“'， - NHCOR''，卤素，-CN，-COOR”和-COR“，其中R”'和 R“”可以相同或不同，并且这些化合物的用途，例如促进皮肤脱屑，刺激表皮更新和/或抵抗皮肤老化的迹象。

    USE OF NOVEL AMINO ACID DERIVATIVES AS AGENTS FOR TREATING HUMAN PERSPIRATION, AND COMPOSITIONS CONTAINING THEM
    6.
    发明申请
    USE OF NOVEL AMINO ACID DERIVATIVES AS AGENTS FOR TREATING HUMAN PERSPIRATION, AND COMPOSITIONS CONTAINING THEM 失效
    使用新型氨基酸衍生物作为治疗人类兴奋剂的药剂，以及含有它们的组合物

    公开(公告)号：US20130164237A1

    公开(公告)日：2013-06-27

    申请号：US13704454

    申请日：2011-06-08

    申请人： Maria Dalko ,  Julien Hitee ,  Thomas Delanne

    发明人： Maria Dalko ,  Julien Hitee ,  Thomas Delanne

    IPC分类号： C07K7/02 ,  A61Q15/00 ,  A61K8/64

    CPC分类号： C07K7/02 ,  A61K8/64 ,  A61Q15/00 ,  C07K7/06

    摘要： The invention relates to the use, as an agent for treating human perspiration, in a cosmetic composition, of amino acid derivatives of formula (I) below: The invention also relates to a cosmetic process for treating perspiration and possibly the body odour associated with human perspiration, especially underarm odour. The invention also relates to novel amino acid derivatives of formula (II) that will be defined in detail hereinbelow, and to cosmetic or dermatological compositions containing them.

    摘要翻译： 本发明涉及在化妆品组合物中用作治疗人类出汗的药剂，以下式（I）的氨基酸衍生物的用途：本发明还涉及用于治疗汗水和可能的与人相关的体臭的美容方法 出汗，特别是腋臭。 本发明还涉及将在下文中详细定义的式（II）的新型氨基酸衍生物和含有它们的化妆品或皮肤病学组合物。

    DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS
    9.
    发明申请
    DERIVATIVE OF GLUCOSE AND VITAMIN F, COMPOSITIONS COMPRISING IT, USES AND PREPARATION PROCESS 有权
    葡萄糖和维生素F的衍生物，包含其的组合物，使用和制备方法

    公开(公告)号：US20090149396A1

    公开(公告)日：2009-06-11

    申请号：US12370006

    申请日：2009-02-12

    申请人： Jean-Francois Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    发明人： Jean-Francois Michelet ,  Maria Dalko ,  Bruno Bernard ,  Didier Semeria ,  Michel Philippe

    IPC分类号： A61K31/7024

    CPC分类号： C07H13/06 ,  A61K8/34 ,  A61K8/602 ,  A61K8/731 ,  A61K31/133 ,  A61K31/192 ,  A61K31/4412 ,  A61K31/7024 ,  A61K31/717 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q7/00 ,  C07H1/00 ,  C07H13/02 ,  Y10S514/88

    摘要： An O-acyl product derived from glucose which may be obtained by partial or total esterification of glucose and of vitamin F, comprising a mixture of esters, for example, monoesters, of glucose and of at least one acid chosen from linoleic acid, oleic acid, palmitic acid and stearic acid, compositions, for example, cosmetic and pharmaceutical compositions, comprising this novel derivative, and their use for improving the condition of head hair and/or other hairs, and, for example, for reducing and/or impeding the loss of head hair and/or other hairs, and/or for inducing and/or stimulating hair growth, as well as a process for preparing O-acyl derivatives mainly in position 6 of glucose, comprising preparing a mixed anhydride by reacting a carboxylic acid with a trimethylacetyl halide, followed by reacting said mixed anhydride formed with glucose.

    摘要翻译： 衍生自葡萄糖的O-酰基产物可以通过葡萄糖和维生素F的部分或全部酯化获得，其包含葡萄糖和至少一种选自亚油酸，油酸的酸的酯，例如单酯的混合物 ，棕榈酸和硬脂酸，组合物，例如包含该新型衍生物的化妆品和药物组合物，以及它们用于改善头发和/或其它毛发的状况的用途，并且例如用于减少和/或阻碍 头发和/或其他毛发的丧失和/或用于诱导和/或刺激毛发生长的方法，以及主要在葡萄糖6位上制备O-酰基衍生物的方法，包括通过使羧酸 与三甲基乙酰卤反应，然后与形成的葡萄糖形成的混合酸酐反应。

    Cosmetic Process for Preventing or Treating the Signs of Skin Ageing or the Orange-Peel Appearance
    10.
    发明申请
    Cosmetic Process for Preventing or Treating the Signs of Skin Ageing or the Orange-Peel Appearance 审中-公开
    用于预防或治疗皮肤老化或橙皮外观的迹象的化妆过程

    公开(公告)号：US20090047224A1

    公开(公告)日：2009-02-19

    申请号：US10580230

    申请日：2004-11-08

    申请人： Maria Dalko ,  Herve Pageon

    发明人： Maria Dalko ,  Herve Pageon

    IPC分类号： A61K8/49 ,  A61K31/4015 ,  A61K31/4025 ,  C07D207/444 ,  C07D407/10

    CPC分类号： C07D405/04 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/69 ,  A61Q19/02 ,  A61Q19/06 ,  A61Q19/08 ,  C07D207/46 ,  C07D211/94

    摘要： The present invention relates to the use of at least one compound capable of cleaving the diketone crosslinking bonds between two proteins, in a composition applied topically to the skin, as an agent for preventing or treating the signs of ageing of the skin or the orange-peel appearance. The above compound is preferably a N-hydroxy imide of formula (I). These N-hydroxy imides have inhibitory properties on the glycation of proteins and also antioxidant properties. The invention also relates to novel N-hydroxy imides included in formula (I) above.

    摘要翻译： 本发明涉及至少一种能够在两种蛋白质之间切割二酮交联键的化合物在局部施用于皮肤的组合物中的用途，作为用于预防或治疗皮肤老化迹象或橙 - 剥皮外观。 上述化合物优选为式（I）的N-羟基酰亚胺。 这些N-羟基酰亚胺对蛋白质的糖基化以及抗氧化性质具有抑制性。 本发明还涉及上述式（I）中所含的新型N-羟基酰亚胺。