公开(公告)号：US5130449A

公开(公告)日：1992-07-14

申请号：US521311

申请日：1990-05-09

Applicant: Michel Lagarde ,  Helmut Traitler ,  Hans-Juergen Wille

Inventor： Michel Lagarde ,  Helmut Traitler ,  Hans-Juergen Wille

IPC: C07C51/42 ,  C11C1/00

CPC classification number: C11C1/007 ,  C07C51/42

Abstract: Substantially pure stearidonic acid is isolated from a mixture of polyunsaturated fatty acids by fractionating at 25% to 35% by weight solution of fatty acids by high-performance reverse-phase liquid chromatography using a mobile phase of 75% to 95% by weight methanol and 25% to 5% by weight water. The isolated stearidonic acid is used to prepare pharmaceutical compositions which are administered to treat cardiovascular and thrombo-embolic diseases associated with platelet aggregation.

Abstract translation: 通过使用75％至95％重量的甲醇的流动相的高性能反相液相色谱法在25％至35％重量的脂肪酸溶液中分馏从多不饱和脂肪酸的混合物中分离出基本上纯的十八碳四烯酸， 25％至5％重量的水。 分离的十八碳四烯酸用于制备药物组合物，其被施用以治疗与血小板聚集相关的心血管和血栓栓塞性疾病。

公开(公告)号：US5243046A

公开(公告)日：1993-09-07

申请号：US836793

申请日：1992-02-14

Applicant: Helmut Traitler ,  Hans-Juergen Wille

Inventor： Helmut Traitler ,  Hans-Juergen Wille

IPC: A61K8/36 ,  A61K8/92 ,  A61K31/20 ,  A61Q19/00 ,  C11C1/00

CPC classification number: A61K8/361 ,  A61K31/20 ,  A61K8/922 ,  A61K8/925 ,  A61Q19/00 ,  C11C1/007

Abstract: A mixture of fatty acids, including derivatives thereof, containing polyunsaturated fatty acids, including derivatives thereof, are reacted with urea in solution. The reaction medium is pumped through at least one scraped-surface heat exchanger for cooling the reaction medium for forming a dispersion of a solid inclusion complex and a liquid phase. The liquid phase which contains a fraction enriched with polyunsaturated fatty acids, including derivatives thereof, then is separated from the inclusion complex.

Abstract translation: 含有多不饱和脂肪酸（包括其衍生物）的脂肪酸（包括其衍生物）的混合物与尿素在溶液中反应。 反应介质被泵送通过至少一个刮表面热交换器，用于冷却反应介质以形成固体包合络合物和液相的分散体。 含有富含多不饱和脂肪酸的馏分（包括其衍生物）的液相然后与包合物分离。

公开(公告)号：US5106542A

公开(公告)日：1992-04-21

申请号：US127781

申请日：1987-12-02

Applicant: Helmut Traitler ,  Hans-Juergen Wille

Inventor： Helmut Traitler ,  Hans-Juergen Wille

IPC: C07C51/487 ,  A61K8/36 ,  A61K8/67 ,  A61K8/92 ,  A61K31/19 ,  A61K31/20 ,  A61Q19/00 ,  C07C51/00 ,  C07C57/00 ,  C07C57/03 ,  C07C57/12 ,  C07C67/00 ,  C07C67/60 ,  C07C69/52 ,  C07C69/58 ,  C11B7/00 ,  C11C1/00

CPC classification number: A61K8/67 ,  A61K31/20 ,  A61K8/361 ,  A61K8/922 ,  A61K8/925 ,  A61Q19/00 ,  C11C1/007

Abstract: A mixture of fatty acids, including derivatives thereof, containing polyunsaturated fatty acids, including derivatives thereof, are fractionated by reacting the mixture with urea in solution for forming a reaction medium which then is pumped at least through one scraped-surface heat exchanger for cooling the reaction medium for forming a dispersion of a solid inclusion complex and a liquid phase. The liquid phase then is separated from the inclusion complex for obtaining a fraction enriched with polyunsaturated fatty acids, including derivatives thereof.

Abstract translation: 含有多不饱和脂肪酸（包括其衍生物）的脂肪酸（包括其衍生物）在内的混合物通过在溶液中与尿素反应形成反应介质进行分馏，所述反应介质至少通过一个刮表面热交换器泵送，以冷却 用于形成固体包合络合物和液相的分散体的反应介质。 然后将液相与包合物分离，以获得富含多不饱和脂肪酸的馏分，包括其衍生物。

公开(公告)号：US5393538A

公开(公告)日：1995-02-28

申请号：US43656

申请日：1993-04-06

Applicant: Oliver Chmiel ,  Eric Raetz ,  Helmut Traitler

Inventor： Oliver Chmiel ,  Eric Raetz ,  Helmut Traitler

IPC: A23G1/00 ,  A23G1/30 ,  A23G1/36 ,  A23G1/42 ,  A23G1/46 ,  A23G1/56 ,  A23L27/20 ,  A23L27/24

CPC classification number: A23G1/30 ,  A23G1/36 ,  A23G1/423 ,  A23G1/46 ,  A23G1/56 ,  A23L27/2028 ,  A23L27/25 ,  C12Y301/01003 ,  C12Y301/01004 ,  A23G2200/12

Abstract: A crumb-flavored milk composition is prepared by incorporating free fatty acids selected from the group consisting of oleic acid, linoleic acid and .alpha.-linolenic acid, or by incorporating a lysolecithin lysate or a milk treated with a modified lipase which preferentially releases unsaturated long-chain fatty acids.

Abstract translation: 通过掺入选自油酸，亚油酸和α-亚麻酸的游离脂肪酸，或通过掺入溶血卵磷脂裂解物或用改性脂肪酶处理的乳，优选释放不饱和长链脂肪酸， 链脂肪酸。

公开(公告)号：US5384256A

公开(公告)日：1995-01-24

申请号：US43357

申请日：1993-04-06

Applicant: Oliver Chmiel ,  Helmut Traitler

Inventor： Oliver Chmiel ,  Helmut Traitler

IPC: A23C9/12 ,  A23G1/00 ,  A23G1/42 ,  A23G3/00 ,  A23G3/36 ,  A23L27/24 ,  C12N9/20 ,  C12N11/02 ,  C12N9/22 ,  C12N9/96 ,  C12N11/08 ,  C12N11/10

CPC classification number: A23G1/423 ,  A23C9/1216 ,  A23G3/366 ,  A23L27/24 ,  A23L27/25 ,  C12N11/02 ,  C12N9/20 ,  C12Y301/01003

Abstract: A native lipase from Mucor javanicus is modified by bonding it to a pectin. The pectin-modified lipase releases fatty acids of identical chain length from a lipidic substrate in a lower saturated-to-unsaturated fatty acid ratio than the native, unmodified, lipase.

Abstract translation: 通过将其与果胶结合来修饰来自木瓜（Mucor javanicus）的天然脂肪酶。 果胶修饰的脂肪酶从脂质底物释放具有比天然的，未修饰的脂肪酶更低的饱和 - 不饱和脂肪酸比例的相同链长的脂肪酸。

公开(公告)号：US5264237A

公开(公告)日：1993-11-23

申请号：US711188

申请日：1991-06-05

Applicant: Helmut Traitler ,  Heike Winter

Inventor： Helmut Traitler ,  Heike Winter

IPC: A23D7/015 ,  A23C9/13 ,  A23C9/152 ,  A23D7/005 ,  A23D9/00 ,  A23D9/007 ,  A23G1/00 ,  A23G1/30 ,  A23G1/38 ,  A23G1/56 ,  A23G3/34 ,  A23G9/32 ,  A23G9/44 ,  A23G9/52 ,  A23L1/24 ,  A23L1/30 ,  A23L1/307 ,  A23L1/308

CPC classification number: A23G1/56 ,  A23C9/1315 ,  A23C9/1528 ,  A23D7/0053 ,  A23D7/0056 ,  A23D9/007 ,  A23G1/38 ,  A23G3/346 ,  A23G9/52 ,  A23L27/60 ,  A23L33/26 ,  A23G2200/08 ,  Y10S426/804

Abstract: Food compositions are prepared by incorporating in a food a diester or triester of fatty acids and an aliphatic C.sub.4-5 diol or triol having secondary alcohol functions. Fried foods may be prepared by frying the food in the presence of the diester or triester.

Abstract translation: 通过在食物中掺入脂肪酸的二酯或三酯和具有仲醇官能团的脂肪族C4-5二醇或三醇制备食品组合物。 油炸食品可以通过在二酯或三酯存在下炸食物来制备。

公开(公告)号：US5395629A

公开(公告)日：1995-03-07

申请号：US975413

申请日：1992-11-12

Applicant: Constantin Bertoli ,  Katalin Hosszu-Sackett ,  Nicholas Melachouris ,  Helmut Traitler

Inventor： Constantin Bertoli ,  Katalin Hosszu-Sackett ,  Nicholas Melachouris ,  Helmut Traitler

IPC: A23D9/00 ,  A23G1/00 ,  A23G1/38 ,  A23G3/00 ,  A23G3/34 ,  A23G9/32 ,  A23G9/52 ,  A23L1/30 ,  A23L1/307 ,  C11B7/00 ,  C11C3/10 ,  A23C15/02

CPC classification number: A23G1/38 ,  A23G3/346 ,  A23G9/327 ,  A23G9/52 ,  A23L33/115 ,  C11B7/0083 ,  C11C3/10 ,  A23G2200/08

Abstract: Fat substitutes are prepared without a molecular distillation step by enzymatically or chemically interesterifying a fully hydrogenated vegetable oil rich in stearic acid (FHLCT) with a medium chain fatty acid triglyceride rich in caproic, caprylic and capric fatty acids (MCT) under conditions such that the amount of tristearin in the interesterified mixture is lower than 5% by weight. The interesterified mixture is bleached and deodorized, and may be used as a substitute for butterfat or vegetable butter, e.g., cocoa butter.

Abstract translation: 在没有分子蒸馏步骤的情况下，通过在富含辛酸，辛酸和癸酸脂肪酸（MCT）的中链脂肪酸甘油三酸酯上酶促或化学地将富含硬脂酸的富含植物油（FHLCT）酯交换成脂肪代替物， 该酯化混合物中的三硬脂酸甘油酯的量低于5重量％。 将酯交换的混合物漂白和除臭，并且可以用作黄油脂或植物黄油，例如可可脂的替代品。

公开(公告)号：US4938984A

公开(公告)日：1990-07-03

申请号：US349896

申请日：1989-05-05

Applicant: Helmut Traitler ,  Heike Winter

Inventor： Helmut Traitler ,  Heike Winter

IPC: A23L1/48 ,  A23C11/00 ,  A23C11/04 ,  A23D7/00 ,  A23D9/00 ,  A23K1/16 ,  A23L1/29 ,  A23L1/30 ,  A61K8/02 ,  A61K8/92 ,  A61K9/00 ,  A61K9/107 ,  A61K31/20 ,  A61K31/23 ,  A61K36/00 ,  A61K36/18 ,  A61K36/185 ,  A61K36/28 ,  A61K36/48 ,  A61K45/08 ,  A61K47/44 ,  A61P3/06 ,  A61P43/00 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q9/02 ,  A61Q19/00 ,  C07C51/48 ,  C11B1/00 ,  C11B1/10 ,  C11B3/00 ,  C11B3/06 ,  C11B3/12 ,  C11B9/02 ,  C11C1/08

CPC classification number: A61K9/0014 ,  A23C11/04 ,  A23D7/003 ,  A23D9/00 ,  A23L33/12 ,  A23L33/40 ,  A61K36/185 ,  A61K36/28 ,  A61K36/48 ,  A61K47/44 ,  A61K8/0212 ,  A61K8/922 ,  A61Q19/00 ,  C07C51/48 ,  C11B1/10 ,  C11B1/104 ,  C11B3/001 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q19/10 ,  A61Q5/00 ,  A61Q9/02 ,  Y10S426/801 ,  Y10S514/844 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/866

Abstract: Food compositions having an added .gamma.-linolenic acid component are provided for human and animal nutrition. The supplemented foods contain an oil extracted from pips of Ribes genus fruits containing at least 4% by weight of .gamma.-linolenic acid. The oil is substantially free from waxes, odorous compounds, colorings and free fatty acids.

公开(公告)号：US4703060A

公开(公告)日：1987-10-27

申请号：US542149

申请日：1983-10-14

Applicant: Helmut Traitler ,  Heike Winter

Inventor： Helmut Traitler ,  Heike Winter

IPC: A23L1/48 ,  A23C11/00 ,  A23C11/04 ,  A23D7/00 ,  A23D9/00 ,  A23K1/16 ,  A23L1/29 ,  A23L1/30 ,  A61K8/02 ,  A61K8/92 ,  A61K9/00 ,  A61K9/107 ,  A61K31/20 ,  A61K31/23 ,  A61K36/00 ,  A61K36/18 ,  A61K36/185 ,  A61K36/28 ,  A61K36/48 ,  A61K45/08 ,  A61K47/44 ,  A61P3/06 ,  A61P43/00 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q9/02 ,  A61Q19/00 ,  C07C51/48 ,  C11B1/00 ,  C11B1/10 ,  C11B3/00 ,  C11B3/06 ,  C11B3/12 ,  C11B9/02 ,  C11C1/08 ,  A61K31/22

CPC classification number: A61K9/0014 ,  A23C11/04 ,  A23D7/003 ,  A23D9/00 ,  A23L33/12 ,  A23L33/40 ,  A61K36/185 ,  A61K36/28 ,  A61K36/48 ,  A61K47/44 ,  A61K8/0212 ,  A61K8/922 ,  A61Q19/00 ,  C07C51/48 ,  C11B1/10 ,  C11B1/104 ,  C11B3/001 ,  A61Q1/02 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q19/10 ,  A61Q5/00 ,  A61Q9/02 ,  Y10S426/801 ,  Y10S514/844 ,  Y10S514/861 ,  Y10S514/863 ,  Y10S514/866

Abstract: The oil of pips of fruits of the Ribes genus is an abundant, cheap source of .gamma.-linolenic acid.It is extracted using solvents from dried and ground residues from the production of juices, preserves and jellies or brandies, liqueurs and schnapps of fruits, such as blackcurrant, redcurrant or gooseberry. According to a preferred embodiment, the residues are treated with ethanol before being extracted with hexane in order to free the oil from most of the free fatty acids, waxes, colorings and odorous compounds.The refined oil is a valuable ingredient in cosmetic, dermatological, dietetic and pharmaceutical compositions.

Abstract translation: Ribes属的果实油是一种丰富而廉价的γ-亚麻酸来源。 使用来自生产果汁，蜜饯和果冻或白兰地，甜酒和黑醋栗，红醋栗或醋栗的水果酱的干酪和残渣的溶剂萃取。 根据一个优选的实施方案，残余物用乙醇处理，然后用己烷萃取，以便从大多数游离脂肪酸，蜡，着色剂和无味化合物中释出油。 精制油是化妆品，皮肤病学，饮食学和药物组合物中的有价值成分。

公开(公告)号：US5989599A

公开(公告)日：1999-11-23

申请号：US427544

申请日：1995-04-24

Applicant: Oliver Chmiel ,  Nicholas Melachouris ,  Helmut Traitler

Inventor： Oliver Chmiel ,  Nicholas Melachouris ,  Helmut Traitler

IPC: A23L23/00 ,  A23L27/60 ,  C07F9/10 ,  C12N11/18 ,  C12P9/00 ,  A23D3/00

CPC classification number: C12P9/00 ,  C12N11/18 ,  C12P13/001

Abstract: Improved process for the interesterification of a phospholipid with a triacyl glycerol is obtained by using an enzyme system containing immobilized lipase and immobilized phospholipase. The phospholipids obtained have better heat stabilized properties and better emulsifying properties than regular lecithin and may be used in emulsion systems or in coatings for instantized powders.

Abstract translation: 通过使用含有固定化脂肪酶和固定化磷脂酶的酶系来获得具有三酰基甘油的磷脂酯交换的改进方法。 获得的磷脂具有比常规卵磷脂更好的热稳定性和更好的乳化性能，并且可以用于乳液体系或用于实例化粉末的涂层中。