公开(公告)号：US20080221886A1

公开(公告)日：2008-09-11

申请号：US12039549

申请日：2008-02-28

Applicant: Michel Colin ,  Daniel Ferro

Inventor： Michel Colin ,  Daniel Ferro

IPC: G10L17/00

CPC classification number: G08G5/0013

Abstract: A system of assistance in the entry of flight data for an aircraft transmitted between a crew on board the aircraft and a ground staff including, a radiofrequency communications link to transmit flight data between the crew and the ground staff. At least one means of sending and one means of receiving data on board the aircraft, wherein the system includes a voice recognition means capable of detecting a piece of data of a predefined type emitted, during the communications call, by the crew or the ground staff and a means of analysis and transcription of this piece of data in digital or alphanumeric form.

Abstract translation: 为飞机上的乘员之间传输的飞机输入飞行数据的协助系统，包括一个射频通信链路，用于在船员和地面工作人员之间传送飞行数据。 至少一种发送装置和一种在飞机上接收数据的装置，其中该系统包括语音识别装置，其能够在通信呼叫期间由机组人员或地勤人员检测出发射的预定类型的数据片段 以及以数字或字母数字形式分析和转录这一数据的手段。

公开(公告)号：US08280741B2

公开(公告)日：2012-10-02

申请号：US12039549

申请日：2008-02-28

Applicant: Michel Colin ,  Daniel Ferro

Inventor： Michel Colin ,  Daniel Ferro

IPC: G10L11/00

CPC classification number: G08G5/0013

Abstract: A system of assistance in the entry of flight data for an aircraft transmitted between a crew on board the aircraft and a ground staff including, a radiofrequency communications link to transmit flight data between the crew and the ground staff. At least one means of sending and one means of receiving data on board the aircraft, wherein the system includes a voice recognition means capable of detecting a piece of data of a predefined type emitted, during the communications call, by the crew or the ground staff and a means of analysis and transcription of this piece of data in digital or alphanumeric form.

Abstract translation: 为飞机上的乘员之间传输的飞机输入飞行数据的协助系统，包括一个射频通信链路，用于在船员和地面工作人员之间传送飞行数据。 至少一种发送装置和一种在飞机上接收数据的装置，其中该系统包括语音识别装置，其能够在通信呼叫期间由机组人员或地勤人员检测出发射的预定类型的数据片段 以及以数字或字母数字形式分析和转录这一数据的手段。

公开(公告)号：US4857653A

公开(公告)日：1989-08-15

申请号：US73154

申请日：1987-07-14

Applicant: Michel Colin ,  Daniel Guenard ,  Francoise Gueritte-Voegelein ,  Pierre Potier

Inventor： Michel Colin ,  Daniel Guenard ,  Francoise Gueritte-Voegelein ,  Pierre Potier

IPC: C07D305/14

CPC classification number: C07D305/14

Abstract: Taxol and 10-deacetyltaxol are prepared from a compound of formula: ##STR1## in which R' represents acetyl or 2,2,2-trichloroethoxycarbonyl radical, by removal of the t-butoxycarbonyl radical, benzoylation of the amine product obtained, and removal of the 2,2,2-trichloroethoxycarbonyl group(s).

Abstract translation: 紫杉醇和10-脱乙酰紫杉醇由下式的化合物制备：其中R'代表乙酰基或2,2,2-三氯乙氧基羰基，通过除去叔丁氧基羰基，得到的胺产物的苯甲酰化和去除 的2,2,2-三氯乙氧基羰基。

公开(公告)号：US4654354A

公开(公告)日：1987-03-31

申请号：US780019

申请日：1985-09-23

Applicant: Braham Shroot ,  Gerard Lang ,  Jean Maignan ,  Michel Colin

Inventor： Braham Shroot ,  Gerard Lang ,  Jean Maignan ,  Michel Colin

IPC: C11D9/50 ,  A61K8/00 ,  A61K8/49 ,  A61K8/67 ,  A61K31/425 ,  A61K31/428 ,  A61P17/00 ,  A61P27/02 ,  A61P29/00 ,  A61P37/00 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q17/04 ,  A61Q19/00 ,  C07D275/02 ,  C07D275/04 ,  C07D513/04 ,  C07D409/00

CPC classification number: A61Q19/007 ,  A61K8/49 ,  A61K8/671 ,  A61Q7/00 ,  A61Q19/005 ,  A61Q19/008 ,  Y10S514/852 ,  Y10S514/859 ,  Y10S514/864

Abstract: The invention provides compounds of formula ##STR1## in which formula R.sub.1 and R.sub.2 are identical or different and denote:(1) taken separately: a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, an unsubstituted phenyl radical or a phenyl radical substituted with a halogen atom, with a C.sub.1 -C.sub.4 alkoxy radical or with a C.sub.1 -C.sub.4 alkoxy radical;(2) taken together either(a) a polymethylene linkage; or(b) a benzene ring; or(c) a cyclic linkage containing a nitrogen atom to constitute an isothiazolopyridinone derivative; m being able to have the values 0 or 1; the group A in the formula (IV) denoting the group ##STR2## where R.sub.8 corresponds to a hydrogen atom, a methyl radical, a hydroxymethyl radical or a --CH.sub.2 O--CO--Ret group. The invention also provides a process for preparing the abovementioned compounds and also drug compositions and cosmetic compositions containing them.

Abstract translation: 本发明提供式（IV）的化合物，其中式R 1和R 2相同或不同，表示：（1）分别取代：氢原子，直链或支链C 1 -C 4烷基，未取代的苯基或未取代的苯基 被卤素原子取代的苯基与C1-C4烷氧基或C1-C4烷氧基取代; （2）（a）聚亚甲基连接; 或（b）苯环; 或（c）含有氮原子构成异噻唑并吡喃酮衍生物的环状键; m能够具有值0或1; 式（IV）中的基团A表示其中R8对应于氢原子，甲基，羟甲基或-CH 2 O-CO-Ret基团的基团。 本发明还提供了制备上述化合物的方法以及含有它们的药物组合物和化妆品组合物。

公开(公告)号：US5268494A

公开(公告)日：1993-12-07

申请号：US893820

申请日：1992-06-04

Applicant: Braham Shroot ,  Christopher Hensby ,  Jean Maignan ,  Gerard Lang ,  Michel Colin

Inventor： Braham Shroot ,  Christopher Hensby ,  Jean Maignan ,  Gerard Lang ,  Michel Colin

IPC: A61K8/14 ,  A61K8/46 ,  A61Q19/00 ,  C07C317/44 ,  C07C323/52 ,  C07C323/60 ,  C07C233/00

CPC classification number: C07C323/52 ,  A61K8/14 ,  A61K8/46 ,  A61Q19/00 ,  C07C317/44 ,  C07C323/60

Abstract: Compounds corresponding to the formula: ##STR1## wherein A represents --CH.sub.2).sub.2 or --C.tbd.C--;n is equal to 0, 1 or 2;R represents hydroxyl, alkoxy having the formula --OR.sub.1, or amino having the formula ##STR2## R.sub.1 represents alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or aralkyl;R.sub.2 and R.sub.3 represent hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, aryl or benzyl;R.sub.2 and R.sub.3 form, with the nitrogen atom, a heterocyclic ring.Application of these compounds in pharmacy and cosmetics.

Abstract translation: 对应于下式的化合物：其中A代表-CH2）2或-C3ONDC-; n等于0,1或2; R表示羟基，具有式-OR 1的烷氧基或具有下式的氨基R1表示烷基，单羟基烷基，多羟基烷基，芳基或芳烷基; R2和R3表示氢，烷基，单羟基烷基，多羟基烷基，芳基或苄基; R2和R3与氮原子形成杂环。 这些化合物在药房和化妆品中的应用。

公开(公告)号：US4924012A

公开(公告)日：1990-05-08

申请号：US331758

申请日：1989-04-03

Applicant: Michel Colin ,  Daniel Guenard ,  Francoise Gueritte-Voegelein ,  Pierre Potier

Inventor： Michel Colin ,  Daniel Guenard ,  Francoise Gueritte-Voegelein ,  Pierre Potier

IPC: A61K31/335 ,  A61K31/337 ,  A61P35/00 ,  A61P35/02 ,  C07D305/14

CPC classification number: C07D305/14 ,  Y02P20/55

Abstract: Process for preparing derivatives of baccatine III and of 10-deacetylbaccatine III, of general formula (I), in which R is hydrogen or acetyl, by condensation of an acid of general formula (II) with a derivative of baccatine III or of 10-deacetylbaccatine III of general formula (III), R.sub.1, R.sub.2 and R.sub.3 denoting hydroxy-protecting groups, followed by the replacement of the protecting groups by hydrogen. ##STR1##

Abstract translation: 通式（I）的酸通过式（II）的酸与杆菌肽III的衍生物或十七烷酸的缩合制备通式（I）的杆菌肽III和10-脱乙酰基巴豆苷III的衍生物的方法，其中R是氢或乙酰基， 通式（III）的脱乙酰基巴豆苷III，R1，R2和R3表示羟基保护基，然后用氢代替保护基。 （一）图像（三）<图像>（四）

公开(公告)号：US4851541A

公开(公告)日：1989-07-25

申请号：US870903

申请日：1986-06-05

Applicant: Jean Maignan ,  Serge Restle ,  Michel Colin

Inventor： Jean Maignan ,  Serge Restle ,  Michel Colin

IPC: A61K31/425 ,  A61K31/428 ,  A61P31/04 ,  A61P31/10 ,  B01J27/00 ,  C07C67/00 ,  C07C313/00 ,  C07C315/02 ,  C07C317/44 ,  C07C319/14 ,  C07C323/41 ,  C07C323/42 ,  C07C323/60 ,  C07C323/61 ,  C07D275/04

CPC classification number: C07D275/04

Abstract: A process for preparing a 4,5-tri or tetramethylene-4-isothiazoline-3-one comprises cyclizing a 2-alkyl or aralkyl thio-1-cycloalkene-1-carboxamide in the form of its sulfoxide in an organic solvent in the presence of a acid chloride and adding to the resulting 4,5-tri or tetramethylene-4-isothiazoline-3-one hydrochloride a mineral or organic base or water so as to free the 4,5-tri or tetramethylene-4-isothiazoline-3-one in the form of a free base.

Abstract translation: 制备4,5-三亚乙基-4-异噻唑啉-3-酮的方法包括在有机溶剂中使其亚砜形式的2-烷基或芳烷基硫代-1-环烯烃-1-甲酰胺在有机溶剂存在下， 加入到所得的4,5-三或四亚甲基-4-异噻唑啉-3-酮盐酸盐的无机或有机碱或水中，以使4,5-三或四亚甲基-4-异噻唑啉-3 - 以自由基的形式。

公开(公告)号：US3950532A

公开(公告)日：1976-04-13

申请号：US251884

申请日：1972-05-10

Applicant: Claude Bouillon ,  Michel Colin

Inventor： Claude Bouillon ,  Michel Colin

IPC: A61K8/49 ,  A61K31/38 ,  A61Q5/00 ,  A61Q19/00 ,  C07D333/32 ,  C07D333/48

CPC classification number: C07D333/48 ,  A61K8/4986 ,  A61Q19/008 ,  A61Q5/006 ,  C07D333/32 ,  Y10S424/01 ,  Y10S424/02 ,  Y10S424/04 ,  Y10S514/852

Abstract: A composition and method for treating the hair and skin characterized by a greasy, unaesthetic appearance to reduce or essentially eliminate this greasy appearance which includes topically applying to a human having hair or skin so characterized a cosmetic composition containing as an active ingredient a cis or trans 3,4-thiolannediol, its cis or trans S-oxide derivatives or its cis or trans S-dioxide derivatives.

Abstract translation: 用于治疗头发和皮肤的组合物和方法，其特征在于油腻，不美观的外观以减少或基本上消除这种油腻外观，其包括局部施用于具有头发或皮肤的人，其特征在于含有作为活性成分的顺式或反式 3,4-硫醇，其顺式或反式S-氧化物衍生物或其顺式或反式S-二氧化物衍生物。

公开(公告)号：US08195997B2

公开(公告)日：2012-06-05

申请号：US11722334

申请日：2005-12-13

Applicant: Anne-Sophie Poutas ,  Michel Colin ,  Maria Julia Ulloa-Sanzo

Inventor： Anne-Sophie Poutas ,  Michel Colin ,  Maria Julia Ulloa-Sanzo

IPC: H03M13/00 ,  G06F11/00

CPC classification number: G08G5/0095

Abstract: A device for inputting digital values includes a digital keyboard configured to be actuated by an operator for inputting figures of a particular digital value, display unit that displays at least the input figures, a validating unit configured to be actuated by the operator for validating a displayed digital value, and an input-aid system having an acquisition unit that acquires the input figures as they are being input and a processing unit that, knowing the digital values which are valid, determines at each input of one figure based on the valid digital values at least one auxiliary figure, which the processing unit associates with a set of already input figures to form a proposed value, and transmits the proposed value to the display unit.

Abstract translation: 用于输入数字值的装置包括：数字键盘，被配置为由操作者致动以输入特定数字值的图形;至少显示输入图形的显示单元;被配置为由操作者致动以验证显示的数字值的验证单元 数字值，以及具有获取单元的输入辅助系统，所述获取单元在输入时获取所述输入图形;以及处理单元，其基于所述有效数字值，知道所述数字值有效，在一个图形的每个输入处确定 至少一个辅助图形，其处理单元与一组已经输入的图形相关联以形成建议的值，并将所提出的值发送到显示单元。

公开(公告)号：US20100023848A1

公开(公告)日：2010-01-28

申请号：US11722334

申请日：2005-12-13

Applicant: Anne-Sophie Poutas ,  Michel Colin ,  Maria Julia Ulloa-Sanzo

Inventor： Anne-Sophie Poutas ,  Michel Colin ,  Maria Julia Ulloa-Sanzo

IPC: G06F11/07 ,  G06F3/048

CPC classification number: G08G5/0095

Abstract: The invention concerns a device (1) comprising a digital keyboard (2) capable of being actuated by an operator for inputting figures of a particular digital value, display means (3) for displaying at least the input figures, validating means (5) capable of being actuated by an operator for validating a displayed digital value, and an input-aid system (6) comprising acquisition means (9) for acquiring the input figures as they are being input, and processing means (10) knowing the digital values which are valid, determining at each input of one figure based on said valid digital values at least one auxiliary figure which it associates with the set of already input figures to form therewith a proposed value, and transmitting said proposed value to the display means (2) for display.

Abstract translation: 本发明涉及一种装置（1），包括能够由操作员致动以输入特定数字值的数字的数字键盘（2），用于至少显示输入图形的显示装置（3），能够显示的验证装置（5） 由操作者致动以验证所显示的数字值;以及输入辅助系统（6），包括用于在输入时获取输入图形的获取装置（9），以及知道数字值的数字值 基于所述有效数字值，确定一个数字的每个输入，至少一个辅助图，其与已经输入的图形的集合相关联以与其一起形成建议的值，并将所述提出的值发送到显示装置（2） 用于显示。