Invention Grant
- Patent Title: Retinoic acid derivatives, process for their preparation and pharmaceutical and cosmetic compositions containing them
- Patent Title (中): 视黄酸衍生物,其制备方法和含有它们的药物和化妆品组合物
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Application No.: US780019Application Date: 1985-09-23
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Publication No.: US4654354APublication Date: 1987-03-31
- Inventor: Braham Shroot , Gerard Lang , Jean Maignan , Michel Colin
- Applicant: Braham Shroot , Gerard Lang , Jean Maignan , Michel Colin
- Applicant Address: FRX Valbonne
- Assignee: Centre International De Recherches Dermatologiques (C.I.R.D.)
- Current Assignee: Centre International De Recherches Dermatologiques (C.I.R.D.)
- Current Assignee Address: FRX Valbonne
- Priority: LUX85556 19840926
- Main IPC: C11D9/50
- IPC: C11D9/50 ; A61K8/00 ; A61K8/49 ; A61K8/67 ; A61K31/425 ; A61K31/428 ; A61P17/00 ; A61P27/02 ; A61P29/00 ; A61P37/00 ; A61Q5/00 ; A61Q5/02 ; A61Q7/00 ; A61Q17/04 ; A61Q19/00 ; C07D275/02 ; C07D275/04 ; C07D513/04 ; C07D409/00
Abstract:
The invention provides compounds of formula ##STR1## in which formula R.sub.1 and R.sub.2 are identical or different and denote:(1) taken separately: a hydrogen atom, a linear or branched C.sub.1 -C.sub.4 alkyl radical, an unsubstituted phenyl radical or a phenyl radical substituted with a halogen atom, with a C.sub.1 -C.sub.4 alkoxy radical or with a C.sub.1 -C.sub.4 alkoxy radical;(2) taken together either(a) a polymethylene linkage; or(b) a benzene ring; or(c) a cyclic linkage containing a nitrogen atom to constitute an isothiazolopyridinone derivative; m being able to have the values 0 or 1; the group A in the formula (IV) denoting the group ##STR2## where R.sub.8 corresponds to a hydrogen atom, a methyl radical, a hydroxymethyl radical or a --CH.sub.2 O--CO--Ret group. The invention also provides a process for preparing the abovementioned compounds and also drug compositions and cosmetic compositions containing them.
Public/Granted literature
- US5812876A DMA controller which can be controlled by host and local processors Public/Granted day:1998-09-22
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