公开(公告)号：US20230065430A1

公开(公告)日：2023-03-02

申请号：US17817766

申请日：2022-08-05

Applicant: LanzaTech, Inc.

Inventor： Zachary Robert Cowden ,  Ching Leang ,  Michael Koepke ,  Rasmus Overgaard Jensen ,  Alexander Paul Mueller

IPC: C12P7/18 ,  C12N1/20 ,  C12N15/52 ,  C12N9/02 ,  C12N9/10 ,  C12N9/88

Abstract: The disclosure provides genetically engineered microorganisms and methods for improved biological production of ethylene glycol and precursors of ethylene glycol. The microorganism of the disclosure produces ethylene glycol or a precursor of ethylene glycol through one or more of 5,10-methylenetetrahydrofolate, oxaloacetate, citrate, malate, and glycine. The disclosure further provides compositions comprising ethylene glycol or polymers of ethylene glycol such as polyethylene terephthalate.

公开(公告)号：US12157908B2

公开(公告)日：2024-12-03

申请号：US16800844

申请日：2020-02-25

Applicant: Northwestern University ,  LanzaTech, Inc.

Inventor： Michael Christopher Jewett ,  Antje Kruger-Gericke ,  Alexander Paul Mueller ,  Michael Koepke

IPC: C12P21/00 ,  C12N1/20 ,  C12N9/12 ,  C12N15/10

Abstract: Disclosed are compositions, methods, and kits for performing cell-free RNA transcription and/or cell-free protein synthesis (CFPS). The disclosed compositions, methods, and kits include or utilize components prepared from a species of Clostridia such as cellular extracts from Clostridium autoethanogenum.

公开(公告)号：US20230407346A1

公开(公告)日：2023-12-21

申请号：US18456894

申请日：2023-08-28

Applicant: LanzaTech, Inc.

Inventor： Sean Dennis Simpson ,  Allan Haiming Gao ,  Robert John Conrado ,  James Daniel Winkler ,  Alexander Paul Mueller ,  Steven Brown ,  Loan Phuong Tran ,  Michael Koepke ,  Christophe Daniel Mihalcea

IPC: C12P7/04

CPC classification number: C12P7/04 ,  C12P39/00

Abstract: The disclosure relates to the system comprising a combination of a primary bioreactor with a secondary bioreactor to convert a gaseous stream comprising CO and optionally H2, or CO2 and H2 to at least one target product. Bioreactors may be any combination of aerobic and anaerobic, batch and continuous. The bioreactors comprise fermenting microorganisms that may typically be bacterial or fungal.

公开(公告)号：US11952607B2

公开(公告)日：2024-04-09

申请号：US17817766

申请日：2022-08-05

Applicant: LanzaTech, Inc.

Inventor： Zachary Robert Cowden ,  Ching Leang ,  Michael Koepke ,  Rasmus Overgaard Jensen ,  Alexander Paul Mueller

IPC: C12N15/74 ,  C12N1/20 ,  C12N9/02 ,  C12N9/10 ,  C12N9/88 ,  C12N15/52 ,  C12P7/18 ,  C12R1/145

CPC classification number: C12P7/18 ,  C12N1/20 ,  C12N9/0008 ,  C12N9/1025 ,  C12N9/1096 ,  C12N9/88 ,  C12N15/52 ,  C12R2001/145 ,  C12Y102/01003 ,  C12Y102/01021 ,  C12Y203/03001 ,  C12Y206/01044 ,  C12Y401/03001

Abstract: The disclosure provides genetically engineered microorganisms and methods for improved biological production of ethylene glycol and precursors of ethylene glycol. The microorganism of the disclosure produces ethylene glycol or a precursor of ethylene glycol through one or more of 5,10-methylenetetrahydrofolate, oxaloacetate, citrate, malate, and glycine. The disclosure further provides compositions comprising ethylene glycol or polymers of ethylene glycol such as polyethylene terephthalate.

公开(公告)号：US20200270665A1

公开(公告)日：2020-08-27

申请号：US16800844

申请日：2020-02-25

Applicant: Northwestern University ,  LanzaTech, Inc.

Inventor： Michael Christopher Jewett ,  Antje Kruger-Gericke ,  Alexander Paul Mueller ,  Michael Koepke

IPC: C12P21/00 ,  C12N1/20 ,  C12N15/10 ,  C12N9/12

Abstract: Disclosed are compositions, methods, and kits for performing cell-free RNA transcription and/or cell-free protein synthesis (CFPS). The disclosed compositions, methods, and kits include or utilize components prepared from a species of Clostridia such as cellular extracts from Clostridium autoethanogenum.

公开(公告)号：US11788103B2

公开(公告)日：2023-10-17

申请号：US16938787

申请日：2020-07-24

Applicant: LanzaTech, Inc.

Inventor： Sean Dennis Simpson ,  Allan Haiming Gao ,  Robert John Conrado ,  James Daniel Winkler ,  Alexander Paul Mueller ,  Steven Brown ,  Loan Phuong Tran ,  Michael Koepke ,  Christophe Daniel Mihalcea

IPC: C12P7/04 ,  C12P39/00

CPC classification number: C12P7/04 ,  C12P39/00

Abstract: The disclosure relates to the combination of a primary fermentation that converts gas to acetate with a secondary fermentation that converts acetate to a target product. Preferably, the gas contains carbon dioxide, such that the disclosure enables the fixation of carbon dioxide into useful products. The fermentations may be any combination of aerobic and anaerobic, batch and continuous. The fermenting microorganisms may typically be bacterial or fungal.

公开(公告)号：US20210024961A1

公开(公告)日：2021-01-28

申请号：US16938787

申请日：2020-07-24

Applicant: LanzaTech, Inc.

Inventor： Sean Dennis Simpson ,  Allan Haiming Gao ,  Robert John Conrado ,  James Daniel Winkler ,  Alexander Paul Mueller ,  Steven Brown ,  Loan Phuong Tran ,  Michael Koepke ,  Christophe Daniel Mihalcea

IPC: C12P7/04

Abstract: The disclosure relates to the combination of a primary fermentation that converts gas to acetate with a secondary fermentation that converts acetate to a target product. Preferably, the gas contains carbon dioxide, such that the disclosure enables the fixation of carbon dioxide into useful products. The fermentations may be any combination of aerobic and anaerobic, batch and continuous. The fermenting microorganisms may typically be bacterial or fungal.