专利检索 ap:("LES LABORATOIRES SERVIER" OR "VERNALIS (R&D) LTD.") AND inv:"Simon BEDFORD" 第 1 页

1.

发明公开
SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS 审中-公开

公开(公告)号：US20240150293A1

公开(公告)日：2024-05-09

申请号：US18262231

申请日：2022-01-11

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD

发明人： Stephen STOKES , Simon BEDFORD , l-Jen CHEN , James Edward Paul DAVIDSON , Nicholas DAVIES , Christopher John GRAHAM , Sean Martin MCKENNA , Johannes W.G. MEISSNER , James Brooke MURRAY , Rachel Jane PARSONS , Stuart RAY , Emma SANDERS , Claire Louise WALMSLEY , Paul Andrew BROUGH , András KOTSCHY , Ágnes PROSZENYÁK , Ádám SINAI , Balázs Károly BÁLINT , Márton CSÉKEI , Márton ZWILLINGER , Rita GARAMVÖLGYI , Szabolcs SIPOS , Vilibald KUN , Zoltán SZABÓ , Maïa CHANRION , Francesca ROCCHETTI , Frédéric COLLAND , Ana Leticia MARAGNO , Laura BRESSON

IPC分类号： C07D215/233 , A61K45/06 , A61P35/00 , C07C229/50 , C07D317/70 , C07D401/12 , C07D405/10 , C07D491/056

CPC分类号： C07D215/233 , A61K45/06 , A61P35/00 , C07C229/50 , C07D317/70 , C07D401/12 , C07D405/10 , C07D491/056

摘要： Compounds of Formula (I):

wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

2.

发明申请
INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM 有权
标题翻译：单和多晶化合物，其制备和含有它们的药物组合物的方法

公开(公告)号：US20160152599A1

公开(公告)日：2016-06-02

申请号：US14905877

申请日：2014-07-22

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD

发明人： Patrick CASARA , Thierry LE DIGUARHER , Jean-Michel HENLIN , Jéröme-Benoit STARCK , Arnaud LE TIRAN , Guillaume DE NANTEUIL , Olivier GENESTE , James Edward Paul DAVIDSON , James Brooke MURRAY , I-Jen CHEN , Claire WALMSLEY , Christopher John GRAHAM , Stuart RAY , Daniel MADDOX , Simon BEDFORD

IPC分类号： C07D401/10 , A61K45/06 , A61K31/496 , C07D471/04 , C07D405/14 , C07D409/14 , A61K31/5377 , A61K31/4725 , C07D401/14

CPC分类号： C07D401/10 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/5377 , A61K45/06 , C07D401/14 , C07D405/14 , C07D409/14 , C07D471/04 , A61K2300/00

摘要： Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description.Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.

摘要翻译： 式（I）化合物：其中Ra，Rb，Rc，Rd，R3，R4，R5，A1，A2，T和W如说明书中所定义。含有该物质的药物可用于治疗涉及细胞凋亡缺陷的病症，如癌症，自身免疫疾病和免疫系统疾病。