专利检索 ap:("LES LABORATOIRES SERVIER" OR "VERNALIS (R&D) LTD.") AND inv:"Frédéric COLLAND" 第 1 页

1.

发明公开
SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS 审中-公开

公开(公告)号：US20240150293A1

公开(公告)日：2024-05-09

申请号：US18262231

申请日：2022-01-11

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD

发明人： Stephen STOKES , Simon BEDFORD , l-Jen CHEN , James Edward Paul DAVIDSON , Nicholas DAVIES , Christopher John GRAHAM , Sean Martin MCKENNA , Johannes W.G. MEISSNER , James Brooke MURRAY , Rachel Jane PARSONS , Stuart RAY , Emma SANDERS , Claire Louise WALMSLEY , Paul Andrew BROUGH , András KOTSCHY , Ágnes PROSZENYÁK , Ádám SINAI , Balázs Károly BÁLINT , Márton CSÉKEI , Márton ZWILLINGER , Rita GARAMVÖLGYI , Szabolcs SIPOS , Vilibald KUN , Zoltán SZABÓ , Maïa CHANRION , Francesca ROCCHETTI , Frédéric COLLAND , Ana Leticia MARAGNO , Laura BRESSON

IPC分类号： C07D215/233 , A61K45/06 , A61P35/00 , C07C229/50 , C07D317/70 , C07D401/12 , C07D405/10 , C07D491/056

CPC分类号： C07D215/233 , A61K45/06 , A61P35/00 , C07C229/50 , C07D317/70 , C07D401/12 , C07D405/10 , C07D491/056

摘要： Compounds of Formula (I):

wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

2.

发明申请
6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER 有权

公开(公告)号：US20220363677A1

公开(公告)日：2022-11-17

申请号：US17630673

申请日：2020-07-28

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD.

发明人： Tibor NOVÁK , James Edward Paul DAVIDSON , Attila PACZAL , Jérôme-Benoît STARCK , András KOTSCHY , James Brooke MURRAY , Simon BEDFORD , Maïa CHANRION , Frédéric COLLAND , Mark Philip DODSWORTH , Andràs HERNER , Ana Leticia MARAGNO , Emma SANDERS , Mátyás Pál TIMÁRI , Paul WEBB

IPC分类号： C07D417/14 , C07D471/04 , C07D487/04 , A61P35/02 , A61P35/00

摘要： Compounds of formula (I): wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments.

3.

发明申请
3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS 有权

公开(公告)号：US20220289734A1

公开(公告)日：2022-09-15

申请号：US17630655

申请日：2020-07-28

申请人： LES LABORATOIRES SERVIER , VERNALIS (R&D) LTD.

发明人： James Edward Paul DAVIDSON , Tibor NOVÁK , Attila PACZAL , András KOTSCHY , Jérôme-Benoît STARCK , James Brooke MURRAY , Simon BEDFORD , Maïa CHANRION , Frédéric COLLAND , Patrice DESOS , Mark Philip DODSWORTH , Petra DUNKEL , Andràs HERNER , Zoltán MADARÁSZ , Ana Leticia MARAGNO , Márk MOLNÁR , Miklós NYERGES , Rachel Jane PARSONS , Monika RUDASOVÁ , Ágnes STROFEK , Marianna SZIGETI , Mátyás Pál TIMÁRI , Paul WEBB

IPC分类号： C07D417/14 , A61K31/501 , A61P35/00 , A61K45/06 , C07D417/12

摘要： Compounds of formula (I): wherein Het1, Het2, R1, R2 and R3 are as defined in the description.