公开(公告)号：US20200330544A1

公开(公告)日：2020-10-22

申请号：US16756757

申请日：2018-10-16

Applicant: LAILA NUTRACEUTICALS ,  P.L. THOMAS-LAILA NUTRACEUTICALS, INC.

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkateswara Rao CHIRRAVURI ,  Venkateswarlu SOMEPALLI ,  Kiran BHUPATHIRAJU

IPC: A61K36/9066 ,  A61K36/75 ,  A23L33/105

Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.

公开(公告)号：US20250000930A1

公开(公告)日：2025-01-02

申请号：US18815434

申请日：2024-08-26

Applicant: LAILA NUTRACEUTICALS ,  P.L. THOMAS-LAILA NUTRACEUTICALS, INC.

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkateswara Rao CHIRRAVURI ,  Venkateswarlu SOMEPALLI ,  Kiran BHUPATHIRAJU

IPC: A61K36/9066 ,  A23L33/105 ,  A61K9/16 ,  A61K36/75

Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.

公开(公告)号：US20210138014A1

公开(公告)日：2021-05-13

申请号：US16492473

申请日：2018-03-08

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Krishanu SENGUPTHA ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI

IPC: A61K36/54 ,  A61K36/22 ,  A61K36/31 ,  A61K36/71 ,  A61K36/8962

Abstract: Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.

公开(公告)号：US20220143124A1

公开(公告)日：2022-05-12

申请号：US17600793

申请日：2020-04-01

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIEAJU ,  Krishanu SENGUPTHA ,  Vankata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI

IPC: A61K36/75 ,  A61K36/23 ,  A61K36/9066 ,  A61P19/02

Abstract: Disclosed herein is Synergistic herbal composition(s) comprising combination of a first ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Murraya koenigii and a second ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Coriandrum sativum or Curcuma amada for improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis. The invention further provides method of improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis in a human or animal.

公开(公告)号：US20250017999A1

公开(公告)日：2025-01-16

申请号：US18897746

申请日：2024-09-26

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC: A61K36/185 ,  A61K45/06 ,  A61P5/26

Abstract: A synergistic herbal composition includes a combination of from 10% to 90% of a first ingredient comprising an extract of a Punica granatum fruit rind obtained by extraction with a solvent selected from the group consisting of water, ethanol, aqueous ethanol, methanol, aqueous methanol, acetone, aqueous acetone, and ethyl acetate; and from 10% to 90% of a second ingredient comprising an extract of a Theobroma cacao seed obtained by extraction with a solvent selected from the group consisting of water, ethanol, aqueous ethanol, methanol, aqueous methanol, acetone, aqueous acetone, and ethyl acetate. The synergistic herbal composition is effective for increasing testosterone levels, inhibiting aromatase activity, increasing mitochondrial biogenesis, and/or increasing mTOR activation in a patient in need thereof.

公开(公告)号：US20230241152A1

公开(公告)日：2023-08-03

申请号：US18000146

申请日：2021-05-29

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju Gokaraju ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Krishanu SENGUPTHA ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC: A61K36/888 ,  A23L33/00 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14

CPC classification number: A61K36/888 ,  A23L33/40 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14 ,  A61K2236/331 ,  A61K2236/333

Abstract: Synergistic Herbal Compositions For Improving Gut Health” The present invention discloses synergistic herbal compositions comprising at least two ingredients selected from extract(s), fraction(s), phytochemical(s), or mixtures thereof derived each one from a different herb selected from Abelmoschus esculentus, Withania somnifera and Amorphophallus paeoniifolius; improving at least one gut health function selected from gut-brain axis, easing of constipation, bowel movement, improved GI motility, digestion and gut immunity; and reducing gut inflammation. The invention further relates to methods of treatment and the use of the compositions.

公开(公告)号：US20230346736A1

公开(公告)日：2023-11-02

申请号：US18012411

申请日：2021-06-23

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI ,  Krishanu SENGUPTHA

IPC: A61K31/22 ,  A61P21/00 ,  A61K33/00

CPC classification number: A61K31/22 ,  A61K33/00 ,  A61P21/00

Abstract: The present invention discloses water-soluble 3-O-acetyl-11-keto-β-boswellic acid compositions comprising 3-O-acetyl-11-keto-β-boswellic acid in combination with a metal ion selected from potassium or sodium in the form of respective metal salt or complex or chelate; process for their preparation; methods of prevention, control and/or treatment of at least one disorder selected from muscle soreness, delayed-onset of muscle soreness (DOMS), muscles tenderness, muscle pain, muscle fatigue, muscle sprain, temporary loss of muscle strength and swelling in muscles.

公开(公告)号：US20210236572A1

公开(公告)日：2021-08-05

申请号：US17054079

申请日：2019-05-08

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC: A61K36/185 ,  A23L33/105 ,  A61P5/24 ,  A61K31/522 ,  A23L33/24 ,  A61K47/38 ,  A61K45/06 ,  A61K31/7048

Abstract: Synergistic herbal compositions comprising combination of a first ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Punica granatum and a second ingredient selected from the extract(s), fraction(s), active compound(s) and phytochemicals or mixtures thereof derived from the plant parts of Theobroma cacao for improving testosterone levels. The invention further provides the method of obtaining at least one health benefit tin related to enhanced anabolic and androgenic activities in the body selected from improving testosterone levels, energy levels, sustained energy, vigor, stamina, healthy aging, cellular longevity, muscle mass, muscle strength sexual function (libido and erectile function) and psychological well-being (mood and focus); and reducing stress in humans and alleviating the symptoms associated with the low levels of testosterone in humans such as loss of libido, loss of erectile function, abdominal obesity, decreased muscle mass and strength, fatigue, mood swing, decreased bone density, decreased motivation, and decreased memory and concentration.

公开(公告)号：US20210046135A1

公开(公告)日：2021-02-18

申请号：US16978905

申请日：2019-03-05

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI ,  Krishanu SENGUPTHA

IPC: A61K36/185 ,  A61K36/752 ,  A61K47/36 ,  A61P3/04 ,  A61K9/00 ,  A61K9/68 ,  A23L33/105 ,  A23L33/00 ,  A23L33/125 ,  A23L29/30

Abstract: The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprising Theobroma cacao and Citrus aurantifolia and optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.