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公开(公告)号：US20250000930A1
公开(公告)日：2025-01-02
申请号：US18815434
申请日：2024-08-26
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Trimurtulu GOLAKOTI , Venkateswara Rao CHIRRAVURI , Venkateswarlu SOMEPALLI , Kiran BHUPATHIRAJU
IPC: A61K36/9066 , A23L33/105 , A61K9/16 , A61K36/75
Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (WAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.
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2.发明申请公开(公告)号：US20200330544A1
公开(公告)日：2020-10-22
申请号：US16756757
申请日：2018-10-16
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Trimurtulu GOLAKOTI , Venkateswara Rao CHIRRAVURI , Venkateswarlu SOMEPALLI , Kiran BHUPATHIRAJU
IPC: A61K36/9066 , A61K36/75 , A23L33/105
Abstract: Synergistic herbal compositions comprising combination of extracts, fractions or phytochemicals or mixtures thereof derived from Moringa oleifera, Murraya koenigii and Curcuma longa for increasing lean body mass and brown adipose tissue; for accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products. The invention further provides a method of increasing lean body mass and brown adipose tissue; accelerating the conversion of the white adipose tissue (WAT) to brown adipose tissue (BAT), inhibiting excessive generation of advanced glycation end (AGE) products and disease conditions associated with increased levels of advanced glycation end (AGE) products in mammals.
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公开(公告)号：US20210338757A1
公开(公告)日：2021-11-04
申请号：US16479798
申请日：2017-01-19
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Trimurtulu GOLAKOTI , Kiran BHUPATHIRAJU , Venkata Kanaka Ranga Raju GOKARAJU , Krishanu SENGUPTHA , Venkata Krishna Raju ALLURI
Abstract: The invention discloses synergistic compositions comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana for inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme or for increasing cGMP levels in a male subject. The invention further discloses a method of inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme, increasing cGMP levels and sexual arousal, treating/alleviating various aspects of male sexual dysfunction or impotence such as erectile dysfunction, loss of libido, or orgasm/ejaculation disorders in a male subject by using a suitable dose of synergistic composition comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana.
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公开(公告)号：US20210138014A1
公开(公告)日：2021-05-13
申请号：US16492473
申请日：2018-03-08
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Trimurtulu GOLAKOTI , Kiran BHUPATHIRAJU , Venkata Kanaka Ranga Raju GOKARAJU , Krishanu SENGUPTHA , Venkata Krishna Raju ALLURI , Venkateswarlu SOMEPALLI
IPC: A61K36/54 , A61K36/22 , A61K36/31 , A61K36/71 , A61K36/8962
Abstract: Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.
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公开(公告)号：US20190201470A1
公开(公告)日：2019-07-04
申请号：US16312150
申请日：2017-06-21
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Kishore Babu GOVADA , Venkata Krishna Raju ALLURI , Nagendra Babu VUTTI , Kiran BHUPATHIRAJU , Venkata Kanaka Ranga Raju GOKARAJU , Trimurtulu GOLAKOTI
CPC classification number: A61K36/68 , A23L27/84 , A23L33/105 , A23V2002/00 , A23V2200/16 , A23V2300/31 , A23V2300/40 , A61K9/1635 , A61K31/7048 , A61K36/19 , A61K36/22 , A61K36/324 , A61K36/38 , A61K36/42 , A61K36/58 , A61K36/81 , A61K47/32 , A61K47/36 , A61K47/44 , A61K2300/00
Abstract: The invention discloses taste masking formulations for bitter natural compounds, selected from the extracts, fraction and pure phytochemicals produced in combination with a synthetic polymer or a natural polymer. The invention also relates to the novel process of producing the taste masking formulations. The invention also relates to taste masking formulations of Bacopa extracts with no bitter taste or negligible bitter taste in combination with synthetic polymers such as Eudragit or natural polymers such as Shellac.
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Patent Agency Ranking
公开(公告)号：US20190192607A1
公开(公告)日：2019-06-27
申请号：US16331370
申请日：2017-09-08
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Kishore Babu GOVADA , Venkata Krishna Raju ALLURI , Nagendra Babu VUTTI , Kiran BHUPATHIRAJU , Venkata Kanaka Ranga Raju GOKARAJU , Trimurtulu GOLAKOTI
CPC classification number: A61K36/84 , A23L27/86 , A23L29/288 , A23V2002/00 , A23V2250/21 , A23V2300/10 , A23V2300/31 , A61K9/0056 , A61K9/146 , A61K47/38
Abstract: The invention discloses odor masking formulations for stench natural compounds, selected from the extracts, fraction and pure phytochemicals that are produced in combination with a natural or synthetic hydrocolloid polymer gum(s). The invention further discloses novel process of producing the odor and taste masking formulations. The invention also discloses taste masking formulations of valerian extracts with no characteristic stench odor & or negligible stench odor in combination with natural hydrocolloid gum such as guar gum, acacia or other polymers. The invention further discloses method of reducing insomnia, anxiety, Attention Deficit Disorder (ADD), Chronic Fatigue Syndrome (CFS) using odor masking formulation of the current invention. Importantly, the said odor masked formulation of the present disclosure helps in improving sleep cycle and helps in efficient functioning of brain.
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7.发明申请SYNERGISTIC ANTI-INFLAMMATORY COMPOSITIONS COMPRISING BOSWELLIA SERRATA EXTRACT 审中-公开包含BOSWELLIA SERRATA萃取物的协同抗炎组合物公开(公告)号：US20150290270A1
公开(公告)日：2015-10-15
申请号：US14735360
申请日：2015-06-10
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Venkata Kanaka Ranga Raju GOKARAJU , Trimurtulu GOLAKOTI , Kiran BHUPATHIRAJU , Venkata Krishna Raju ALLURI
IPC: A61K36/324
CPC classification number: A61K36/324
Abstract: The present invention discloses synergistic nutraceutical or pharmaceutical or dietary supplement anti-inflammatory compositions comprising therapeutically effective combination of an extract selectively enriched in 3-O-acetyl-1 1-keto-β-boswellic acid (AKBA) derived from Boswellia serrata and Boswellia serrata non-acidic resin extract (BNRE). The composition(s) can be used to prevent, control and treat inflammation and several inflammatory related diseases including asthma, osteoarthritis, rheumatoid arthritis, endothelial dysfunction and the like. The invention further discloses the amelioration of pro-inflammatory biomarker proteins or molecules, whose expression/production is altered during inflammatory diseases.
Abstract translation: 本发明公开了协同营养药物或药物或膳食补充剂抗炎组合物，其包含选自富含源于乳香乳杆菌（Boswellia serrata）和乳香型乳杆菌（Boswellia）的3-O-乙酰基-11-酮基 - 巴豆威酸（AKBA） 锯齿酸非酸性树脂提取物（BNRE）。 组合物可用于预防，控制和治疗炎症和若干炎性相关疾病，包括哮喘，骨关节炎，类风湿性关节炎，内皮功能障碍等。 本发明还公开了在炎性疾病期间其表达/产生被改变的促炎生物标记蛋白或分子的改善。
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公开(公告)号：US20220096588A1
公开(公告)日：2022-03-31
申请号：US17489915
申请日：2021-09-30
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Venkata Kanaka Ranga Raju GOKARAJU , Trimurtulu GOLAKOTI , Kiran BHUPATHIRAJU
IPC: A61K36/9066 , A61K36/48 , A61K9/00 , A61K31/353 , A61K31/715
Abstract: A method for treating a disease condition such as inflammation, arthritis, joint pain, rheumatoid arthritis, osteoarthritis, chronic non-rheumatoid arthritis, and collagen degradation in a patient in need thereof involves administering to the patient an effective amount of a composition:
a) a Tamarindus indica seed extract comprising an alcohol or hydroalcohol extract of a Tamarindus indica seed, wherein the alcohol or hydroalcohol extract comprises proanthocyanidins; and
b) a Curcuma longa rhizome extract comprising curcuminoids,
wherein the Tamarindus indica seed extract and the Curcuma longa rhizome extract are used in a ratio ranging from 1:4 to 4:1.-
公开(公告)号：US20190336555A1
公开(公告)日：2019-11-07
申请号：US16349518
申请日：2017-11-11
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Trimurtulu GOLAKOTI , Kiran BHUPATHIRAJU , Krishanu SENGUPTHA , Venkata Kanaka Ranga Raju GOKARAJU , Venkata Krishna Raju ALLURI
IPC: A61K36/68 , A61K36/80 , A61K45/06 , A23L33/105
Abstract: The present invention relates to synergistic compositions comprising extracts or fractions derived from Bacopa monnieri in combination with extracts or fractions derived from Terminalia chebula for improving brain health, memory/mental condition, enhancing brain/mental functions such as cognition, memory, learning, retention, communication and for treating neurodegenerative diseases/disorders such as Alzheimer's disease, Parkinson's disease etc. The invention further relates to method of improving brain health and brain functions selected from cognition, memory, memory retention, information recall, intelligence, motivation, attention, concentration, learning power and communication and to alleviate disease conditions related to cognition and memory deficits in a mammal by supplementing the mammal with an effective dose of the synergistic composition comprising at least one extract or fraction derived from Bacopa monnieri in combination with at least extract or fraction derived from Terminalia chebula.
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公开(公告)号：US20170290875A1
公开(公告)日：2017-10-12
申请号：US15518107
申请日：2015-10-09
Applicant: LAILA NUTRACEUTICALS
Inventor： Ganga Raju GOKARAJU , Rama Raju GOKARAJU , Venkata Kanaka Ranga Raju GOKARAJU , Trimurtulu GOLAKATI , Kiran BHUPATHIRAJU
IPC: A61K36/9066 , A61K31/715 , A61K31/353 , A61K36/48 , A61K9/00
CPC classification number: A61K36/9066 , A61K9/0014 , A61K9/0053 , A61K31/353 , A61K31/715 , A61K36/48 , A61K2236/33 , A61K2300/00
Abstract: The present invention relates to synergistic compositions for the treatment of one or more associated conditions of arthritis or rheumatoid arthritis osteoarthritis. More particularly, novel synergistic compositions which comprises a combination of therapeutically effective amounts of: a) an alcoholic/hydroalcoholic extract of Tamarindus indica seed comprising proanthocyanidins either alone or in combination with water extract of Tamarindus indica seed comprising polysaccharides, b) a Curcuma longa rhizome extract comprising curcuminoids, c) optionally containing pharmaceutically or nutraceutically or dietetically acceptable carriers/excipients. The invention also relates to a method of treating one or more associated conditions of arthritis or rheumatoid arthritis or osteoarthritis using synergistic composition.
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