公开(公告)号：US20220143124A1

公开(公告)日：2022-05-12

申请号：US17600793

申请日：2020-04-01

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIEAJU ,  Krishanu SENGUPTHA ,  Vankata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI

IPC: A61K36/75 ,  A61K36/23 ,  A61K36/9066 ,  A61P19/02

Abstract: Disclosed herein is Synergistic herbal composition(s) comprising combination of a first ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Murraya koenigii and a second ingredient selected from the extract(s), fraction(s), phytochemical(s) and mixtures thereof derived from Coriandrum sativum or Curcuma amada for improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis. The invention further provides method of improving cartilage growth/repair/regeneration, improving joint mobility, reducing cartilage breakdown, reducing joint pain, reducing stiffness, reducing inflammation and/or treating/alleviating symptoms associated with osteoarthritis in a human or animal.

公开(公告)号：US20230241152A1

公开(公告)日：2023-08-03

申请号：US18000146

申请日：2021-05-29

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju Gokaraju ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Krishanu SENGUPTHA ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI

IPC: A61K36/888 ,  A23L33/00 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14

CPC classification number: A61K36/888 ,  A23L33/40 ,  A23L33/105 ,  A61K36/185 ,  A61K36/81 ,  A61P1/14 ,  A61K2236/331 ,  A61K2236/333

Abstract: Synergistic Herbal Compositions For Improving Gut Health” The present invention discloses synergistic herbal compositions comprising at least two ingredients selected from extract(s), fraction(s), phytochemical(s), or mixtures thereof derived each one from a different herb selected from Abelmoschus esculentus, Withania somnifera and Amorphophallus paeoniifolius; improving at least one gut health function selected from gut-brain axis, easing of constipation, bowel movement, improved GI motility, digestion and gut immunity; and reducing gut inflammation. The invention further relates to methods of treatment and the use of the compositions.

公开(公告)号：US20190336555A1

公开(公告)日：2019-11-07

申请号：US16349518

申请日：2017-11-11

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Krishanu SENGUPTHA ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Venkata Krishna Raju ALLURI

IPC: A61K36/68 ,  A61K36/80 ,  A61K45/06 ,  A23L33/105

Abstract: The present invention relates to synergistic compositions comprising extracts or fractions derived from Bacopa monnieri in combination with extracts or fractions derived from Terminalia chebula for improving brain health, memory/mental condition, enhancing brain/mental functions such as cognition, memory, learning, retention, communication and for treating neurodegenerative diseases/disorders such as Alzheimer's disease, Parkinson's disease etc. The invention further relates to method of improving brain health and brain functions selected from cognition, memory, memory retention, information recall, intelligence, motivation, attention, concentration, learning power and communication and to alleviate disease conditions related to cognition and memory deficits in a mammal by supplementing the mammal with an effective dose of the synergistic composition comprising at least one extract or fraction derived from Bacopa monnieri in combination with at least extract or fraction derived from Terminalia chebula.

公开(公告)号：US20210338757A1

公开(公告)日：2021-11-04

申请号：US16479798

申请日：2017-01-19

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Krishanu SENGUPTHA ,  Venkata Krishna Raju ALLURI

IPC: A61K36/22 ,  A61K36/38 ,  A61K45/06 ,  A23L33/105 ,  A61K9/00 ,  A61P15/10

Abstract: The invention discloses synergistic compositions comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana for inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme or for increasing cGMP levels in a male subject. The invention further discloses a method of inhibiting the expression/production/activity of Phosphodiesterase 5 (PDE5) enzyme, increasing cGMP levels and sexual arousal, treating/alleviating various aspects of male sexual dysfunction or impotence such as erectile dysfunction, loss of libido, or orgasm/ejaculation disorders in a male subject by using a suitable dose of synergistic composition comprising extracts, fractions or pure compounds derived from at least two herbs selected from Punica granatum, Mangifera indica and Garcinia mangostana.

公开(公告)号：US20210138014A1

公开(公告)日：2021-05-13

申请号：US16492473

申请日：2018-03-08

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Krishanu SENGUPTHA ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI

IPC: A61K36/54 ,  A61K36/22 ,  A61K36/31 ,  A61K36/71 ,  A61K36/8962

Abstract: Synergistic herbal compositions for Testosterone boosting comprising at least two ingredients selected from the extracts, fractions or pure phytochemicals derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The present invention also describes a synergistic composition comprising at least one testosterone booster ingredient selected from the extracts, fractions or pure phytochemical derived from Punica granatum, Cinnamomum zeylanicum, Nigella sativa, Brassica nigra and Mangifera indica and at least one aromatase inhibitor ingredient selected from the extracts, fractions or pure phytochemicals derived from Allium cepa, Tamarindus indica and Cinnamomum tamala for improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans. The invention further provides methods of improving testosterone levels and alleviating symptoms associated with low levels of testosterone hormone in humans.

公开(公告)号：US20230346736A1

公开(公告)日：2023-11-02

申请号：US18012411

申请日：2021-06-23

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Kiran BHUPATHIRAJU ,  Venkata Krishna Raju ALLURI ,  Venkateswarlu SOMEPALLI ,  Krishanu SENGUPTHA

IPC: A61K31/22 ,  A61P21/00 ,  A61K33/00

CPC classification number: A61K31/22 ,  A61K33/00 ,  A61P21/00

Abstract: The present invention discloses water-soluble 3-O-acetyl-11-keto-β-boswellic acid compositions comprising 3-O-acetyl-11-keto-β-boswellic acid in combination with a metal ion selected from potassium or sodium in the form of respective metal salt or complex or chelate; process for their preparation; methods of prevention, control and/or treatment of at least one disorder selected from muscle soreness, delayed-onset of muscle soreness (DOMS), muscles tenderness, muscle pain, muscle fatigue, muscle sprain, temporary loss of muscle strength and swelling in muscles.

公开(公告)号：US20210046135A1

公开(公告)日：2021-02-18

申请号：US16978905

申请日：2019-03-05

Applicant: LAILA NUTRACEUTICALS

Inventor： Ganga Raju GOKARAJU ,  Venkata Kanaka Ranga Raju GOKARAJU ,  Rama Raju GOKARAJU ,  Trimurtulu GOLAKOTI ,  Kiran BHUPATHIRAJU ,  Venkateswarlu SOMEPALLI ,  Venkata Krishna Raju ALLURI ,  Krishanu SENGUPTHA

IPC: A61K36/185 ,  A61K36/752 ,  A61K47/36 ,  A61P3/04 ,  A61K9/00 ,  A61K9/68 ,  A23L33/105 ,  A23L33/00 ,  A23L33/125 ,  A23L29/30

Abstract: The invention discloses synergistic herbal composition comprising combination of first ingredient selected from extracts, fractions, phytochemicals and mixtures thereof derived from Theobroma cacao and a second ingredient selected from extracts, fractions, phytochemical and mixtures thereof derived from Citrus aurantifolia for obtaining at least one health benefit selected from preventing, controlling or treating obesity and/or overweight; improving lean body mass, improving the browning of White Adipose Tissue/improving formation of brown adipose tissue, increasing basal metabolic rate/resting energy expenditure, increasing thermogenesis, improving thyroid function, maintaining healthy body weight, increasing satiety/, supporting weight loss, improving fat loss and maintaining a slim body. The invention further discloses synergistic herbal compositions comprising Theobroma cacao and Citrus aurantifolia and optionally comprises at least one ingredient selected from pharmaceutically acceptable excipient/diluent/carrier; methods of treatment and use for the prevention and treatment of obesity/overweight or improving lean body mass or resting energy expenditure in a human or animal.