公开(公告)号：US20210371827A1

公开(公告)日：2021-12-02

申请号：US16963278

申请日：2018-11-13

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sang Yong JON ,  Min Suk CHOI ,  Sung Gap IM ,  Daeyoup LEE ,  Seung Jung YU ,  Yoon Jung CHOI

IPC: C12N5/095 ,  C12N5/00 ,  A61K35/13

Abstract: The present invention relates to a method or kit for producing cancer stem cell spheroids, and a method of screening of drugs for treating cancer cell resistance using the prepared cancer stem cell spheroid, and it can conveniently produce cancer stem cell spheroids, and the prepared cancer stem cell spheroids can be effectively utilized for screening drugs for treating cancer cell resistance.

公开(公告)号：US20190233788A1

公开(公告)日：2019-08-01

申请号：US16315761

申请日：2017-07-05

Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Sung Gap IM ,  Eun Jung LEE ,  Ji Eung BAEK ,  Young Hak CHO ,  Seung Jung YU ,  Go Ro CHOI

IPC: C12M1/22 ,  B05D7/02 ,  C08J5/18 ,  C08L57/06 ,  B05D1/00

CPC classification number: C12M23/10 ,  B05D1/60 ,  B05D7/02 ,  C08F212/36 ,  C08F226/06 ,  C08J5/18 ,  C08L25/16 ,  C08L39/08 ,  C08L57/06 ,  C08L2203/02 ,  C08L2203/16 ,  C12N5/00 ,  C12N5/0018 ,  C23C16/452

Abstract: The present invention provides a culture plate comprising a copolymer formed from a first monomer for forming a thin film having high surface free energy and a second monomer for forming a thin film having low surface free energy, a method for producing the culture plate, and a method for producing and transferring a cell aggregate in the form of a cell sheet by using the culture plate. The present invention has the effect of producing a cell aggregate in the form of a cell sheet through an easy and simple process in comparison with prior art.