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公开(公告)号:US20170037136A1
公开(公告)日:2017-02-09
申请号:US15228582
申请日:2016-08-04
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Galina Obmolova , Anish Suri , Fang Teng , Alexey Teplyakov , Hong Zhou , Jocelyn Leu
IPC: C07K16/28 , G01N33/68 , C07K16/42 , A61K39/395 , A61K45/06
Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Abstract translation: 本发明涉及特异性结合CD154的拮抗性抗体,编码抗体或片段的多核苷酸,以及制备和使用上述物质的方法。
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公开(公告)号:US20200317794A1
公开(公告)日:2020-10-08
申请号:US16853786
申请日:2020-04-21
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Galina Obmolova , Anish Suri , Fang Teng , Alexey Teplyakov , Hong Zhou , Jocelyn Leu
Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US20200317791A1
公开(公告)日:2020-10-08
申请号:US16839179
申请日:2020-04-03
Applicant: Janssen Biotech, Inc.
Inventor: Ryan Eberwine , Anne Fourie , Paul H. Kim , Carl L. Manthey , Hong Zhou
IPC: C07K16/28
Abstract: Anti-HLA-C6 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases, such as autoimmune diseases.
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公开(公告)号:US10669343B2
公开(公告)日:2020-06-02
申请号:US15228582
申请日:2016-08-04
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Galina Obmolova , Anish Suri , Fang Teng , Alexey Teplyakov , Hong Zhou , Jocelyn Leu
IPC: A61K39/395 , C07K16/28 , A61K45/06
Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US10544229B2
公开(公告)日:2020-01-28
申请号:US15281670
申请日:2016-09-30
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Paul Kim , Michael Quigley , Andressa Smith , Alexey Teplyakov , Hong Zhou
Abstract: The present invention relates to agonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments, and methods of making and using the foregoing.
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公开(公告)号:US11421037B2
公开(公告)日:2022-08-23
申请号:US16853786
申请日:2020-04-21
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Galina Obmolova , Anish Suri , Fang Teng , Alexey Teplyakov , Hong Zhou , Jocelyn Leu
Abstract: The present invention relates to antagonistic antibodies specifically binding CD154, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US20180355043A1
公开(公告)日:2018-12-13
申请号:US16062255
申请日:2016-12-16
Applicant: Janssen Biotech, Inc.
Inventor: Christian Martinez , Qiang Chen , Melissa Swiecki , Robert Kuhn , Hong Zhou , Karen Duffy , Stephane Becart , Chichi Huang , Xiefan Lin-Schmidt , Sheng-Jiun Wu , Jeffrey Luo , Galina Obmolova , Robin Ernst
IPC: C07K16/28
CPC classification number: C07K16/2833 , C07K2317/21 , C07K2317/56 , C07K2317/92
Abstract: The present invention relates antibodies or antigen-binding fragments thereof specifically binding HLA-DR, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号:US20170088624A1
公开(公告)日:2017-03-30
申请号:US15281670
申请日:2016-09-30
Applicant: Janssen Biotech, Inc.
Inventor: Johan Fransson , Paul Kim , Michael Quigley , Andressa Smith , Alexey Teplyakov , Hong Zhou
IPC: C07K16/28 , A61K45/06 , C07K16/42 , A61K39/395
Abstract: The present invention relates to agonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments, and methods of making and using the foregoing.
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公开(公告)号:US11299545B2
公开(公告)日:2022-04-12
申请号:US16839179
申请日:2020-04-03
Applicant: Janssen Biotech, Inc.
Inventor: Ryan Eberwine , Anne Fourie , Paul H. Kim , Carl L. Manthey , Hong Zhou
Abstract: Anti-HLA-C6 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, methods of producing the antibodies, and methods of using the antibodies for treating or preventing diseases, such as autoimmune diseases.
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公开(公告)号:US20190048089A1
公开(公告)日:2019-02-14
申请号:US15763673
申请日:2016-09-30
Applicant: Janssen Biotech, Inc.
Inventor: Holger Babbe , Nathan Felix , Johan Fransson , Paul Kim , Michael Scully , Hong Zhou
Abstract: The present invention relates to antagonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments thereof, and methods of making and using the foregoing.
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