公开(公告)号：US10544229B2

公开(公告)日：2020-01-28

申请号：US15281670

申请日：2016-09-30

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Paul Kim ,  Michael Quigley ,  Andressa Smith ,  Alexey Teplyakov ,  Hong Zhou

IPC: C07K16/28 ,  A61K39/395 ,  A61K45/06 ,  C07K16/42 ,  A61K47/68 ,  C07K16/46 ,  A61K39/00

Abstract: The present invention relates to agonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments, and methods of making and using the foregoing.

公开(公告)号：US20190048089A1

公开(公告)日：2019-02-14

申请号：US15763673

申请日：2016-09-30

Applicant: Janssen Biotech, Inc.

Inventor： Holger Babbe ,  Nathan Felix ,  Johan Fransson ,  Paul Kim ,  Michael Scully ,  Hong Zhou

IPC: C07K16/28 ,  C07K16/46 ,  A61K47/68 ,  A61K45/06 ,  C07K16/42 ,  A61K39/395

Abstract: The present invention relates to antagonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments thereof, and methods of making and using the foregoing.

公开(公告)号：US20170088624A1

公开(公告)日：2017-03-30

申请号：US15281670

申请日：2016-09-30

Applicant: Janssen Biotech, Inc.

Inventor： Johan Fransson ,  Paul Kim ,  Michael Quigley ,  Andressa Smith ,  Alexey Teplyakov ,  Hong Zhou

IPC: C07K16/28 ,  A61K45/06 ,  C07K16/42 ,  A61K39/395

Abstract: The present invention relates to agonistic antibodies specifically binding human CD40, polynucleotides encoding the antibodies or antigen-binding fragments, and methods of making and using the foregoing.