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公开(公告)号：US10882907B2
公开(公告)日：2021-01-05
申请号：US16014153
申请日：2018-06-21
Applicant: Gilead Sciences, Inc.
Inventor： Doug Rehder , Matthew R. Schenauer , Heather Stephenson , Nathan D. Thomsen
Abstract: Multispecific antibodies (e.g., bispecific antibodies) that bind to HIV gp120 and CD3 are disclosed. Also disclosed are methods of using such antibodies to treat or prevent HIV infection.
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公开(公告)号：US11655285B2
公开(公告)日：2023-05-23
申请号：US17110876
申请日：2020-12-03
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , John Corbin , Craig S. Pace , Nathan D. Thomsen , Xue Zhang
CPC classification number: C07K16/1063 , A61K2039/505 , C07K2317/33 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
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公开(公告)号：US20190211083A1
公开(公告)日：2019-07-11
申请号：US16273753
申请日：2019-02-12
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , John Corbin , Craig S. Pace , Nathan D. Thomsen , Xue Zhang
IPC: C07K16/10
CPC classification number: C07K16/1063 , A61K2039/505 , C07K2317/33 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/92 , C07K2317/94
Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
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公开(公告)号：US20230056252A1
公开(公告)日：2023-02-23
申请号：US17409260
申请日：2021-08-23
Applicant: Gilead Sciences, Inc.
Inventor： Manuel Baca , Wade S. Blair , Brian A. Carr , Sheila B. Clancy , Joshua Goldsmith , Magdeleine S. Hung , Manu Kanwar , Brian Moldt , Mark Nagel , Craig S. Pace , YenRu Pan , Heather T. Stephenson , Nathan D. Thomsen
Abstract: Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
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公开(公告)号：US20200223907A1
公开(公告)日：2020-07-16
申请号：US16460094
申请日：2019-07-02
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , Magdeleine S. Hung , Manu Kanwar , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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Patent Agency Ranking
公开(公告)号：US10239935B2
公开(公告)日：2019-03-26
申请号：US15379157
申请日：2016-12-14
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , John Corbin , Craig S. Pace , Nathan D. Thomsen , Xue Zhang
Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
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公开(公告)号：US12195524B2
公开(公告)日：2025-01-14
申请号：US17409260
申请日：2021-08-23
Applicant: Gilead Sciences, Inc.
Inventor： Manuel Baca , Brian A. Carr , Sheila B. Clancy , Craig S. Pace , Heather T. Stephenson , Nathan D. Thomsen
Abstract: Provided are multi-specific antigen binding molecules, including bispecific antibodies, that bind to CD3 and an HIV antigen, including HIV envelope protein gp120. Also provided are methods of using such antigen binding molecules to treat or prevent HIV infection.
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公开(公告)号：US11597759B2
公开(公告)日：2023-03-07
申请号：US16867924
申请日：2020-05-06
Applicant: Gilead Sciences, Inc.
Inventor： Tomas Cihlar , Joshua Goldsmith , George Kukolj , Craig S. Pace , Doug Rehder , Matthew R. Schenauer , Derek Dean Sloan , Heather Theresa Stephenson , Nathan D. Thomsen
IPC: C07K16/10 , A61K47/68 , A61K51/10 , A61P31/18 , C07K16/28 , G01N33/53 , A61K39/395 , A61K39/42 , A61K39/00
Abstract: Multispecific antibodies (e.g., bispecific antibodies) that bind to HIV gp120 and CD3 are disclosed. Also disclosed are methods of using such antibodies to treat or prevent HIV infection.
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公开(公告)号：US20220089698A1
公开(公告)日：2022-03-24
申请号：US17496250
申请日：2021-10-07
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , Magdeleine S. Hung , Manu Kanwar , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
Abstract: Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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公开(公告)号：US10882898B2
公开(公告)日：2021-01-05
申请号：US16273753
申请日：2019-02-12
Applicant: Gilead Sciences, Inc.
Inventor： Mini Balakrishnan , Brian A. Carr , John Corbin , Craig S. Pace , Nathan D. Thomsen , Xue Zhang
Abstract: The present invention provides novel anti-HIV antibodies with improved therapeutic properties, related pharmaceutical compositions, and methods of use thereof.
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