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公开(公告)号：US20200223907A1
公开(公告)日：2020-07-16
申请号：US16460094
申请日：2019-07-02
发明人： Mini Balakrishnan , Brian A. Carr , Magdeleine S. Hung , Manu Kanwar , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
摘要： Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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公开(公告)号：US11597759B2
公开(公告)日：2023-03-07
申请号：US16867924
申请日：2020-05-06
发明人： Tomas Cihlar , Joshua Goldsmith , George Kukolj , Craig S. Pace , Doug Rehder , Matthew R. Schenauer , Derek Dean Sloan , Heather Theresa Stephenson , Nathan D. Thomsen
IPC分类号： C07K16/10 , A61K47/68 , A61K51/10 , A61P31/18 , C07K16/28 , G01N33/53 , A61K39/395 , A61K39/42 , A61K39/00
摘要： Multispecific antibodies (e.g., bispecific antibodies) that bind to HIV gp120 and CD3 are disclosed. Also disclosed are methods of using such antibodies to treat or prevent HIV infection.
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公开(公告)号：US20220089698A1
公开(公告)日：2022-03-24
申请号：US17496250
申请日：2021-10-07
发明人： Mini Balakrishnan , Brian A. Carr , Magdeleine S. Hung , Manu Kanwar , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
摘要： Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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公开(公告)号：US20240034774A1
公开(公告)日：2024-02-01
申请号：US18365869
申请日：2023-08-04
发明人： Mini Balakrishnan , Brian A. Carr , Magdeleine S. Hung , Manu Kanwar , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
CPC分类号： C07K16/1063 , A61P31/18 , A61K45/06
摘要： Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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公开(公告)号：US11168130B2
公开(公告)日：2021-11-09
申请号：US16460094
申请日：2019-07-02
发明人： Mini Balakrishnan , Brian A. Carr , Craig S. Pace , Doug Rehder , Matthew Robert Schenauer , Loredana Serafini , Heather Theresa Stephenson , Nathan D. Thomsen , Helen Yu , Xue Zhang
摘要： Antibodies that bind to HIV gp120 and neutralize HIV are disclosed. Also disclosed are methods of using such antibodies alone or in combination with other therapeutic agents to treat or prevent HIV infection.
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公开(公告)号：US20200377592A1
公开(公告)日：2020-12-03
申请号：US16867924
申请日：2020-05-06
发明人： Tomas Cihlar , Joshua Goldsmith , George Kukolj , Craig S. Pace , Doug Rehder , Derek Dean Sloan , Heather Theresa Stephenson , Nathan D. Thomsen
摘要： Multispecific antibodies (e.g., bispecific antibodies) that bind to HIV gp120 and CD3 are disclosed. Also disclosed are methods of using such antibodies to treat or prevent HIV infection.
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