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公开(公告)号:US20220064286A1
公开(公告)日:2022-03-03
申请号:US17526338
申请日:2021-11-15
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20190119376A1
公开(公告)日:2019-04-25
申请号:US15994583
申请日:2018-05-31
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K45/06 , A61K38/17 , C07K16/30 , A61K39/395
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20180186875A1
公开(公告)日:2018-07-05
申请号:US15895741
申请日:2018-02-13
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210253693A1
公开(公告)日:2021-08-19
申请号:US17244682
申请日:2021-04-29
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20210032328A1
公开(公告)日:2021-02-04
申请号:US17064464
申请日:2020-10-06
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , C07K16/30 , A61K39/395 , A61K45/06 , A61K38/17
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20140161822A1
公开(公告)日:2014-06-12
申请号:US14077414
申请日:2013-11-12
Applicant: Genentech, Inc.
Inventor: Min XU , Mercedesz BALAZS , Ning CHAI , Nancy Chiang , Henry CHIU , Zhaoyu JIN , Zhonghua LIN , Patrick LUPARDUS , Gerald R. NAKAMURA , Hyunjoo PARK , Lee SWEM
IPC: C07K16/10
CPC classification number: C07K16/1018 , A61K31/215 , A61K31/235 , A61K31/24 , A61K39/42 , A61K2039/505 , A61K2039/507 , A61K2039/545 , C07K2317/21 , C07K2317/33 , C07K2317/56 , C07K2317/76 , C07K2317/94 , A61K2300/00
Abstract: The present invention provides anti-hemagglutinin antibodies, compositions comprising anti-hemagglutinin antibodies, and methods of using the same.
Abstract translation: 本发明提供抗血凝素抗体,包含抗血凝素抗体的组合物及其使用方法。
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公开(公告)号:US20240418731A1
公开(公告)日:2024-12-19
申请号:US18762502
申请日:2024-07-02
Applicant: Genentech, Inc.
Inventor: Lelia DELAMARRE , Patrick LUPARDUS , Ira MELLMAN , Mahesh YADAV , Suchit JHUNJHUNWALA , Jennie LILL
IPC: G01N33/68 , A61K39/00 , C12Q1/6886 , G01N33/569
Abstract: The present disclosure provides methods of identifying a disease-specific immunogenic peptide through a series of selection steps. Immunogenic epitopes identified by methods of the present disclosure are applicable for use in peptide-based immunotherapy, preferably cancer therapy. Furthermore, the methods of the present disclosure may be performed in a high-throughput manner and serve as a means of personalized vaccine development and therapy. Also provided are compositions of immunogenic peptides as well as methods of treatment comprising said compositions.
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公开(公告)号:US20230279102A1
公开(公告)日:2023-09-07
申请号:US18062956
申请日:2022-12-07
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , C07K16/30 , A61K45/06 , A61K39/395
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/34 , C07K2317/56 , C07K2317/90 , C07K2317/94
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20160069895A1
公开(公告)日:2016-03-10
申请号:US14850864
申请日:2015-09-10
Applicant: GENENTECH, INC.
Inventor: Lelia DELAMARRE , Patrick LUPARDUS , Ira MELLMAN , Mahesh YADEV , Suchit JHUNJHUNWALA , Jennie LILL
IPC: G01N33/68 , A61K39/00 , A61K39/395 , C12Q1/68
CPC classification number: G01N33/6848 , A61K39/00 , A61K39/0011 , A61K2039/55516 , A61K2039/55561 , C12Q1/6886 , C12Q2600/156 , G01N33/56977 , G01N33/6878 , G01N2333/70539 , G01N2800/7028
Abstract: The present disclosure provides methods of identifying a disease-specific immunogenic peptide through a series of selection steps. Immunogenic epitopes identified by methods of the present disclosure are applicable for use in peptide-based immunotherapy, preferably cancer therapy. Furthermore, the methods of the present disclosure may be performed in a high-throughput manner and serve as a means of personalized vaccine development and therapy. Also provided are compositions of immunogenic peptides as well as methods of treatment comprising said compositions.
Abstract translation: 本公开提供了通过一系列选择步骤鉴定疾病特异性免疫原性肽的方法。 通过本公开的方法鉴定的免疫原性表位可应用于基于肽的免疫治疗,优选癌症治疗。 此外,本公开的方法可以以高通量方式进行,并且用作个性化疫苗开发和治疗的手段。 还提供了免疫原性肽的组合物以及包含所述组合物的治疗方法。
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公开(公告)号:US20240117037A1
公开(公告)日:2024-04-11
申请号:US18345587
申请日:2023-06-30
Applicant: Genentech, Inc.
Inventor: Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K39/395 , A61K45/06 , C07K16/30
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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