公开(公告)号：US20140161822A1

公开(公告)日：2014-06-12

申请号：US14077414

申请日：2013-11-12

Applicant: Genentech, Inc.

Inventor： Min XU ,  Mercedesz BALAZS ,  Ning CHAI ,  Nancy Chiang ,  Henry CHIU ,  Zhaoyu JIN ,  Zhonghua LIN ,  Patrick LUPARDUS ,  Gerald R. NAKAMURA ,  Hyunjoo PARK ,  Lee SWEM

IPC: C07K16/10

CPC classification number: C07K16/1018 ,  A61K31/215 ,  A61K31/235 ,  A61K31/24 ,  A61K39/42 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/76 ,  C07K2317/94 ,  A61K2300/00

Abstract: The present invention provides anti-hemagglutinin antibodies, compositions comprising anti-hemagglutinin antibodies, and methods of using the same.

Abstract translation: 本发明提供抗血凝素抗体，包含抗血凝素抗体的组合物及其使用方法。

公开(公告)号：US20220177551A1

公开(公告)日：2022-06-09

申请号：US17681665

申请日：2022-02-25

Applicant: Genentech, Inc.

Inventor： Meredith Carroll HAZEN ,  Zhonghua LIN ,  Dhaya SESHASAYEE

IPC: C07K16/00 ,  C12N5/0781

Abstract: The instant technology generally relates to improved methods for producing antibodies, antibody libraries, hybridomas, hybridoma libraries, etc. For example, these methods increase the number of antigen-specific B cells produced, increase the number of hybridomas, and/or increase the number of monoclonal antibodies that can be made in a given production cycle.

公开(公告)号：US20160168230A1

公开(公告)日：2016-06-16

申请号：US15042436

申请日：2016-02-12

Applicant: Genentech, Inc.

Inventor： Min XU ,  Mercedesz BALAZS ,  Ning CHA ,  Nancy CHIANG ,  Henry CHIU ,  Zhaoyu JIN ,  Zhonghua LIN ,  Patrick LUPARDUS ,  Gerald R. NAKAMURA ,  Hyunjoo PARK ,  Lee SWEM

IPC: C07K16/10 ,  A61K39/42 ,  A61K31/24

CPC classification number: C07K16/1018 ,  A61K31/215 ,  A61K31/235 ,  A61K31/24 ,  A61K39/42 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/545 ,  C07K2317/21 ,  C07K2317/33 ,  C07K2317/56 ,  C07K2317/76 ,  C07K2317/94 ,  A61K2300/00

Abstract: The present invention provides anti-hemagglutinin antibodies, compositions comprising anti-hemagglutinin antibodies, and methods of using the same.

公开(公告)号：US20140134638A1

公开(公告)日：2014-05-15

申请号：US14077407

申请日：2013-11-12

Applicant: Genentech, Inc.

Inventor： Juan ZHANG ,  Mercedesz BALAZS ,  Ning CHAI ,  Henry CHIU ,  Wyne Pun LEE ,  Zhonghua LIN ,  Patrick LUPARDUS ,  Lee SWEM

IPC: C12N5/0789

CPC classification number: C07K16/1018 ,  C07K16/00 ,  C07K16/065 ,  C07K16/1282 ,  C07K2317/30 ,  C12N5/0635

Abstract: The present invention relates to methods for enrichment of antigen-specific plasmablasts. The methods are useful for the identification of antibodies, including rare antibodies which recognize more than one antigen.

Abstract translation: 本发明涉及用于富集抗原特异性浆细胞的方法。 该方法可用于鉴定抗体，包括识别多于一种抗原的罕见抗体。