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公开(公告)号：US20230040403A1
公开(公告)日：2023-02-09
申请号：US17876682
申请日：2022-07-29
申请人： GeoVax, Inc.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
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公开(公告)号：US11896657B2
公开(公告)日：2024-02-13
申请号：US17584231
申请日：2022-01-25
申请人： GeoVax, Inc.
IPC分类号： A61K39/12 , C12N15/863 , C12N15/86 , A61K39/00
CPC分类号： A61K39/12 , C12N15/86 , C12N15/863 , A61K2039/5256 , A61K2039/5258 , C12N2710/24141 , C12N2710/24143 , C12N2760/10034 , C12N2760/14134 , C12N2760/14234
摘要： The compositions and methods are described for generating an immune response to a hemorrhagic fever virus such as ebolavirus, Marburgvirus, or arenavirus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Ebolavirus (such as a member of species Zaire ebolavirus), a member of genus Marburgvirus (such as a member of species Marburg marburgvirus), or a member of genus Arenavirus (such as a member of species Lassa virus) in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by ebolavirus, Marburgvirus, or arenavirus.
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3.发明申请公开(公告)号：US20190290745A1
公开(公告)日：2019-09-26
申请号：US16068527
申请日：2017-01-09
申请人： GEOVAX INC.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
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4.发明公开公开(公告)号：US20240156940A1
公开(公告)日：2024-05-16
申请号：US18394555
申请日：2023-12-22
申请人： GeoVax, Inc.
IPC分类号： A61K39/12 , C12N15/86 , C12N15/863
CPC分类号： A61K39/12 , C12N15/86 , C12N15/863 , A61K2039/5256 , C12N2710/24141 , C12N2710/24143 , C12N2760/10034 , C12N2760/14134 , C12N2760/14234
摘要： The compositions and methods are described for generating an immune response to a hemorrhagic fever virus such as ebolavirus, Marburgvirus, or arenavirus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Ebolavirus (such as a member of species Zaire ebolavirus), a member of genus Marburgvirus (such as a member of species Marburg marburgvirus), or a member of genus Arenavirus (such as a member of species Lassa virus) in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by ebolavirus, Marburgvirus, or arenavirus.
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公开(公告)号：US20200289633A1
公开(公告)日：2020-09-17
申请号：US16796350
申请日：2020-02-20
申请人： GeoVax, Inc.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases
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公开(公告)号：US11413341B2
公开(公告)日：2022-08-16
申请号：US16796350
申请日：2020-02-20
申请人： GeoVax, Inc.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
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公开(公告)号：US20220152190A1
公开(公告)日：2022-05-19
申请号：US17584231
申请日：2022-01-25
申请人： GeoVax, Inc.
IPC分类号： A61K39/12 , C12N15/863 , C12N15/86
摘要： The compositions and methods are described for generating an immune response to a hemorrhagic fever virus such as ebolavirus, Marburgvirus, or arenavirus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Ebolavirus (such as a member of species Zaire ebolavirus), a member of genus Marburgvirus (such as a member of species Marburg marburgvirus), or a member of genus Arenavirus (such as a member of species Lassa virus) in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by ebolavirus, Marburgvirus, or arenavirus.
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公开(公告)号：US11278607B2
公开(公告)日：2022-03-22
申请号：US16068527
申请日：2017-01-09
申请人： GEOVAX INC.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
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