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1.发明申请公开(公告)号：US20190290745A1
公开(公告)日：2019-09-26
申请号：US16068527
申请日：2017-01-09
申请人： GEOVAX INC.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
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公开(公告)号：US20230040403A1
公开(公告)日：2023-02-09
申请号：US17876682
申请日：2022-07-29
申请人： GeoVax, Inc.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
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3.发明申请公开(公告)号：US20200282036A1
公开(公告)日：2020-09-10
申请号：US16648693
申请日：2018-09-18
申请人： GEOVAX, INC.
IPC分类号： A61K39/015 , A61K47/69 , A61K9/00 , A61P33/06
摘要： The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
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公开(公告)号：US20190030157A1
公开(公告)日：2019-01-31
申请号：US16074947
申请日：2017-02-01
申请人： GEOVAX INC.
摘要： The compositions and methods are described for generating an immune response to a flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
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公开(公告)号：US20220313808A1
公开(公告)日：2022-10-06
申请号：US17726254
申请日：2022-04-21
申请人： Geovax, Inc.
IPC分类号： A61K39/015 , A61K47/69 , A61P33/06 , A61K9/00
摘要： The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
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公开(公告)号：US11413341B2
公开(公告)日：2022-08-16
申请号：US16796350
申请日：2020-02-20
申请人： GeoVax, Inc.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to an antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens as a fusion product with a viral glycoprotein and matrix protein for generating a protective immune response to a subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat diseases.
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公开(公告)号：US11278607B2
公开(公告)日：2022-03-22
申请号：US16068527
申请日：2017-01-09
申请人： GEOVAX INC.
发明人： Harriet Robinson , Arban Domi , Michael Hellerstein , Farshad Guirakhoo , Nathanael Paul McCurley
摘要： The compositions and methods are described for generating an immune response to a tumor associated antigen such as MUC1. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a neoplasm expressing the tumor associated antigen in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat neoplasms and associated diseases.
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公开(公告)号：US11857611B2
公开(公告)日：2024-01-02
申请号：US17726254
申请日：2022-04-21
申请人： Geovax, Inc.
IPC分类号： A61K39/015 , A61K47/69 , A61P33/06 , A61K9/00 , A61K39/00
CPC分类号： A61K39/015 , A61K9/0019 , A61K47/6901 , A61P33/06 , A61K2039/5256 , A61K2039/54
摘要： The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
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公开(公告)号：US11638750B2
公开(公告)日：2023-05-02
申请号：US17000768
申请日：2020-08-24
申请人： GEOVAX, INC.
摘要： The compositions and methods are described for generating an immune response to a flavivirus such as Zika virus. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to a member of genus Flavivirus (such as a member of species Zika virus), in the subject to which the vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat an infection caused by Flavivirus.
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公开(公告)号：US11311612B2
公开(公告)日：2022-04-26
申请号：US16648693
申请日：2018-09-18
申请人： GEOVAX, INC.
IPC分类号： A61K39/015 , A61K47/69 , A61P33/06 , A61K9/00 , A61K39/00
摘要： The compositions and methods are described for generating an immune response to a Plasmodium antigen. The compositions and methods described herein relate to a modified vaccinia Ankara (MVA) vector encoding one or more viral antigens for generating a protective immune response to malaria by expressing the Plasmodium antigen in the subject to which the MVA vector is administered. The compositions and methods of the present invention are useful both prophylactically and therapeutically and may be used to prevent and/or treat malaria.
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