公开(公告)号：US20240374804A1

公开(公告)日：2024-11-14

申请号：US18779848

申请日：2024-07-22

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: A61M1/34 ,  A61M1/36 ,  A61M1/38 ,  G01N33/48 ,  G16H10/60 ,  G16H40/60

Abstract: A system and a method for collecting plasma has a separator, a donor line, an anticoagulant line, a touchscreen, and a controller. The controller controls operation of the system and receives donor parameters electronically from a donor management system. The controller uses a target volume for plasma product and/or raw plasma which is based at least in part on donor height and weight used to calculate total donor blood volume, the target volume for plasma product and/or raw plasma based on the total donor blood volume. The controller controls the system to operate at least three draw and return phases to withdraw whole blood from a donor and separate the whole blood into the plasma product and the red blood cells and to return the red blood cells to the donor

公开(公告)号：US20220400992A1

公开(公告)日：2022-12-22

申请号：US17861437

申请日：2022-07-11

Applicant: FENWAL, INC.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs ,  Katherine N. Radwanski

IPC: A61B5/15

Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donor's weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.

公开(公告)号：US11412967B2

公开(公告)日：2022-08-16

申请号：US17306099

申请日：2021-05-03

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs ,  Katherine N. Radwanski

IPC: A61B5/15

Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donor's weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.

公开(公告)号：US20210402072A1

公开(公告)日：2021-12-30

申请号：US17354673

申请日：2021-06-22

Applicant: Fenwal, Inc.

Inventor： Samantha M. Planas ,  Amit J. Patel ,  Jonathan Elicson ,  Andrew Vazquez

IPC: A61M1/34 ,  A61M1/36 ,  A61M1/26

Abstract: A system with container volume tracking includes a pump receiving a line connected to a tracked container, an air sensor to detect air in the line, and a controller coupled to pump and sensor. The controller is configured to monitor pump operation, and determine a volume removed from the container based thereon. If the volume removed is less than a first percentage of a target volume and there is air, continue operation after an air purge. If the volume removed is more than the first percentage and less than a second percentage and if there is air, prompt the user for an input, and continue operation after an air purge if a first input is received or end operation if a second input is received. If the volume removed is more than the second percentage and if there is air, end operation.

公开(公告)号：US10688233B2

公开(公告)日：2020-06-23

申请号：US14577456

申请日：2014-12-19

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Melissa A. Thill

IPC: A61M1/34 ,  A61M1/16 ,  A61M1/36 ,  A61M1/26 ,  C12N5/078

Abstract: Methods and systems for processing biological fluid are disclosed. The methods and systems allow for processing of biological fluid to continue in the event that certain non-operator-correctable hardware errors of a non-critical nature are detected during such processing.

公开(公告)号：US20160089486A1

公开(公告)日：2016-03-31

申请号：US14500166

申请日：2014-09-29

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas

IPC: A61M1/38 ,  A61M1/36 ,  A61M1/02

CPC classification number: A61M1/382 ,  A61M1/0231 ,  A61M1/029 ,  A61M1/262 ,  A61M1/265 ,  A61M1/30 ,  A61M1/303 ,  A61M1/305 ,  A61M1/308 ,  A61M1/342 ,  A61M1/3437 ,  A61M1/3496 ,  A61M1/3626 ,  A61M1/3646 ,  A61M1/3693 ,  A61M1/38 ,  A61M2205/18 ,  A61M2205/3375 ,  A61M2205/3393

Abstract: A method is provided for controlling the return phase of a blood separation procedure having a draw phase in which blood is drawn through an access or donor line, is separated, and a fluid, such as a cellular concentrate, is flowed into a reservoir, and a return phase in which fluid is flowed from the reservoir through the donor line. The method comprises flowing fluid from the reservoir through the donor line in a steady state return; monitoring the donor line for the presence of air; and, upon detecting air in the donor line, determining the amount of fluid remaining in the reservoir. Then, either i) the donor line is purged, if the amount of fluid remaining in the reservoir exceeds a predetermined amount, and the steady state return of fluid from the reservoir through the donor line is resumed; or ii) if the amount of fluid remaining in the reservoir does not exceed the predetermined amount, the return phase is ended by terminating the flow of fluid from the reservoir through the donor line.

Abstract translation: 提供了一种方法，用于控制血液分离程序的返回阶段，该血液分离程序具有抽吸阶段，在该阶段，血液通过进入或供体管线被抽取，被分离，并且诸如细胞浓缩物的流体流入储存器，以及 流体从储存器通过供体管线流动的返回阶段。 该方法包括使流体从稳定状态返回中流过供体管; 监测供体线是否存在空气; 并且在检测供体管线中的空气时，确定储存器中剩余的流体的量。 然后，i）如果储存器中残留的流体的量超过预定量，并恢复流体从储存器通过供体管线的稳定状态，则排出供体管线; 或ii）如果储存器中剩余的流体量不超过预定量，则通过终止来自储存器的流体通过供体管线的流动来终止返回阶段。

公开(公告)号：US20240404692A1

公开(公告)日：2024-12-05

申请号：US18733064

申请日：2024-06-04

Applicant: FENWAL, INC.

Inventor： Brian C. Case ,  Lan T. Nguyen ,  Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: G16H40/60 ,  A61B34/10 ,  A61M1/34 ,  G06F21/31 ,  G08B3/10 ,  G08B5/22 ,  G16H10/60

Abstract: A system and method for collecting plasma includes drawing whole blood from a donor, combining anticoagulant with the whole blood from the donor, separating the whole blood into a plasma product and a second blood component and sending the plasma product to a collection container. A controller determines a total blood volume for a donor based on donor weight, height and gender. The system comprises a touchscreen for receiving a confirming user input and a scanning device configured to scan a bar code associated with a donor. The system and method operate a plurality of draw and return phases.

公开(公告)号：US20240023855A1

公开(公告)日：2024-01-25

申请号：US18371795

申请日：2023-09-22

Applicant: FENWAL, INC.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs ,  Katherine N. Radwanski

IPC: A61B5/15

CPC classification number: A61B5/150992 ,  A61B5/150229 ,  A61B5/150343 ,  A61B5/150251 ,  A61B2560/0487

Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donors weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.

公开(公告)号：US11801001B2

公开(公告)日：2023-10-31

申请号：US17861437

申请日：2022-07-11

Applicant: FENWAL, INC.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs ,  Katherine N. Radwanski

IPC: A61B5/15

CPC classification number: A61B5/150992 ,  A61B5/150229 ,  A61B5/150251 ,  A61B5/150343 ,  A61B2560/0487

Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which a volume of plasma product (i.e., anticoagulated plasma) so that that the targeted volume of pure plasma in the plasma product is determined based on donor-specific characteristics. In particular, the targeted amount of pure plasma to be collected is based on the weight, or the weight and the height, of the donor. The targeted volume of pure plasma to be collected, TVP, may be a multiple of the donor's weight. Alternatively, TVP may be a multiple of the donor's total blood volume, TBV, with the TBV of the donor being determined based on the donor's weight and height. A target volume for the plasma product to be collected, TVPP, is established, and separation of whole blood into a plasma component and a second component continues until the volume of plasma product in a collection container equals TVPP.

公开(公告)号：US11383013B2

公开(公告)日：2022-07-12

申请号：US16739441

申请日：2020-01-10

Applicant: Fenwal, Inc.

Inventor： Amit J. Patel ,  Samantha M. Planas ,  Walter T. Watts ,  Kyungyoon Min ,  Daniel R. Boggs

IPC: A61M1/34 ,  A61M1/36 ,  A61M1/38 ,  G01N33/48 ,  G16H10/60

Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the volume/weight of anticoagulated plasma that is collected is optimized. In one example, a nomogram is provided that utilizes the donor's hematocrit to calculate the volume/weight of raw plasma within a plasma product having the maximum volume permitted by the FDA nomogram. In a plasmapheresis procedure having multiple collection phases followed by a reinfusion cycle in which concentrated red blood cells are returned to the donor, the volume of plasma product to be collected is calculated prior to the start of each collection cycle to account for the donor's increasing hematocrit, thus resulting in a greater total volume of plasma product to be collected during the plasmapheresis procedure.