公开(公告)号：US4329458A

公开(公告)日：1982-05-11

申请号：US238328

申请日：1981-02-26

Applicant: Erich Klauke ,  Ernst Kysela ,  Arnd Stuwe ,  Alfons Dorlars

Inventor： Erich Klauke ,  Ernst Kysela ,  Arnd Stuwe ,  Alfons Dorlars

IPC: C07B61/00 ,  C07D251/28

CPC classification number: C07D251/28

Abstract: The present invention relates to a process for the preparation of 2,4,6-trifluoro-1,3,5-triazine (TFT) from 2,4,6-trichloro-1,3,5-triazine (TCT) or from mixed chlorinated/fluorinated 1,3,5-triazines by fluorination with sodium fluoride in dipolar aprotic solvents.The process is characterized in that TCT or mixed chlorinated/fluorinated 1,3,5-triazines or mixtures thereof are metered into a suspension of sodium fluoride in a dipolar, aprotic solvent, which is warmed to a temperature of between 120.degree. C. and 220.degree. C. and optionally contains a further solvent.

Abstract translation: 本发明涉及从2,4,6-三氯-1,3,5-三嗪（TCT）制备2,4,6-三氟-1,3,5-三嗪（TFT）或从 混合氯化/氟化1,3,5-三嗪通过氟化氟化物在偶极非质子溶剂中氟化。 该方法的特征在于将TCT或混合氯化/氟化1,3,5-三嗪或其混合物计量加入到氟化钠在偶极非质子溶剂中的悬浮液中，将其温热至120℃至 220℃，任选地含有另外的溶剂。

公开(公告)号：US4161593A

公开(公告)日：1979-07-17

申请号：US870601

申请日：1978-01-18

Applicant: Erich Klauke ,  Ernst Kysela ,  Alfons Dorlars

Inventor： Erich Klauke ,  Ernst Kysela ,  Alfons Dorlars

IPC: B01J27/00 ,  C07B61/00 ,  C07D237/12 ,  C07D239/30 ,  C07D251/28

CPC classification number: C07D251/28

Abstract: Process for the preparation of triazines containing a mixture of chlorine and fluorine substituents, characterized in that cyanuric chloride is heated with cyanuric fluoride to temperatures from 30.degree.-300.degree. C. in the presence of suitable catalysts.

Abstract translation: 用于制备含有氯和氟取代基混合物的三嗪的方法，其特征在于在合适的催化剂存在下，将氰尿酰氯加热至30-300℃。

公开(公告)号：US4549994A

公开(公告)日：1985-10-29

申请号：US630490

申请日：1984-07-13

Applicant: Hermann Hagemann ,  Erich Klauke ,  Ernst Kysela

Inventor： Hermann Hagemann ,  Erich Klauke ,  Ernst Kysela

IPC: A01N47/12 ,  C07C51/00 ,  C07C51/58 ,  C07C53/50 ,  C07C67/00 ,  C07C239/00 ,  C07C271/10 ,  C07C271/14

CPC classification number: C07C53/50 ,  C07C51/58

Abstract: A process for the preparation of a compound according to claim 1, comprising reacting a compound of the formula ##STR1## in which R.sup.3, R.sup.4 and R.sup.5 each independently is CH.sub.3 or CH.sub.2 Cl, at least one of the radicals R.sup.3, R.sup.4 and R.sup.5 being CH.sub.2 Cl,with a metal fluoride at elevated temperature. The products are new and useful as intermediates for making other compounds, especially carbamate insecticide synergists.

Abstract translation: 一种制备根据权利要求1的化合物的方法，包括使下式化合物（其中R 3，R 4和R 5各自独立地为CH 3或CH 2 Cl）反应，基团R 3，R 4和R 5中的至少一个为CH 2 Cl ，在高温下用金属氟化物。 该产品作为制备其他化合物，特别是氨基甲酸酯杀虫剂增效剂的中间体是新的和有用的。

公开(公告)号：US4351974A

公开(公告)日：1982-09-28

申请号：US233413

申请日：1981-02-11

Applicant: Bernd Baasner ,  Erich Klauke ,  Ernst Kysela

Inventor： Bernd Baasner ,  Erich Klauke ,  Ernst Kysela

IPC: B01J23/74 ,  B01J27/00 ,  C07B61/00 ,  C07C17/00 ,  C07C17/12 ,  C07C25/13 ,  C07C67/00

CPC classification number: C07C17/12

Abstract: In the preparation of 3-bromo-4-fluorotoluene by reacting 4-fluorotoluene with bromine, the improvement which comprises effecting the bromination in glacial acetic acid in the presence of iodine and iron or an iron salt. As a result the proportion of 3-bromo-4-fluorotoluene relative to its 2-bromo-4-fluorotoluene isomer is markedly increased.

Abstract translation: 在通过4-氟甲苯与溴反应制备3-溴-4-氟甲苯的过程中，其改进包括在碘和铁或铁盐存在下在冰醋酸中进行溴化。 结果，3-溴-4-氟甲苯相对于其2-溴-4-氟甲苯异构体的比例明显增加。

公开(公告)号：US4216173A

公开(公告)日：1980-08-05

申请号：US7271

申请日：1979-01-29

Applicant: Ernst Kysela ,  Reinhard Lantzsch ,  Erich Klauke

Inventor： Ernst Kysela ,  Reinhard Lantzsch ,  Erich Klauke

IPC: C07C17/23 ,  C07C17/00 ,  C07C21/19 ,  C07C27/00 ,  C07C29/136 ,  C07C29/143 ,  C07C33/42 ,  C07C67/00 ,  C07C11/20 ,  C07C21/04

CPC classification number: C07C33/423 ,  C07C17/35 ,  C07C29/143

Abstract: A 1,1-dichloro-4-methyl-3-hydroxy-pent-1-ene and a process for its production.

Abstract translation: 1,1-二氯-4-甲基-3-羟基 - 戊-1-烯及其制备方法。

公开(公告)号：US4792635A

公开(公告)日：1988-12-20

申请号：US713513

申请日：1985-03-19

Applicant: Albrecht Marhold ,  Erich Klauke ,  Ernst Kysela

Inventor： Albrecht Marhold ,  Erich Klauke ,  Ernst Kysela

IPC: C07B31/00 ,  C07B37/04 ,  C07B41/06 ,  C07C17/00 ,  C07C17/263 ,  C07C22/08 ,  C07C25/18 ,  C07C41/00 ,  C07C43/225 ,  C07C45/00 ,  C07C45/28 ,  C07C45/33 ,  C07C45/36 ,  C07C49/76 ,  C07C49/813 ,  C07C49/84 ,  C07C67/00 ,  C07C211/52 ,  C07C213/00 ,  C07C225/22 ,  C07C313/00 ,  C07C319/20 ,  C07C323/03 ,  C07C323/20 ,  C07D317/46 ,  C07D319/20 ,  C08G65/38 ,  C08G65/40 ,  C07C49/80

CPC classification number: C08G65/38 ,  C07C43/225 ,  C07C45/28 ,  C07C45/36 ,  C07C49/813 ,  C07C49/84 ,  C07D317/46 ,  C07D319/20

Abstract: Symmetric benzophenones substituted by groups containing fluorine are prepared by reacting aromatic compounds substituted by groups containing fluorine with formaldehyde and/or a formaldehyde derivative, with the addition of hydrogen fluoride, fluorosulphonic acid and/or sulphuric acid, to give the corresponding diphenylmethanes and oxidizing these. The symmetric benzophenones substituted by groups containing fluorine are used for the preparation of polyether ketones by reacting them with diols. New symmetric benzophenones substituted by groups containing fluorine are also disclosed.

Abstract translation: 由含氟基团取代的对称二苯甲酮通过使含有氟基团的芳族化合物与甲醛和/或甲醛衍生物反应，加入氟化氢，氟磺酸和/或硫酸来制备相应的二苯基甲烷并将其氧化 。 由含氟基团取代的对称二苯甲酮用于通过与二醇反应来制备聚醚酮。 还公开了由含氟基团取代的新的对称二苯甲酮。

公开(公告)号：US4588844A

公开(公告)日：1986-05-13

申请号：US575962

申请日：1984-02-01

Applicant: Ernst Kysela ,  Erich Klauke

Inventor： Ernst Kysela ,  Erich Klauke

IPC: C07C45/00 ,  C07C45/28 ,  C07C45/56 ,  C07C47/52 ,  C07C47/542 ,  C07C47/55 ,  C07C47/565 ,  C07C47/575 ,  C07C47/58 ,  C07C67/00 ,  C07C313/00 ,  C07C319/20 ,  C07C323/22 ,  C07C45/42

CPC classification number: C07C323/00 ,  C07C45/565 ,  C07C47/55 ,  C07C47/575

Abstract: Aromatic aldehydes are prepared by formylating the corresponding aromatic compounds with urotropine in the presence of hydrogen fluoride. By the described process certain new aromatic aldehydes can be prepared.

Abstract translation: 通过在氟化氢存在下，用乌洛托品甲酰化相应的芳族化合物来制备芳族醛。 通过描述的方法，可以制备某些新的芳族醛。

公开(公告)号：US5362909A

公开(公告)日：1994-11-08

申请号：US968603

申请日：1992-10-29

Applicant: Erich Klauke ,  Uwe Petersen ,  Klaus Grohe

Inventor： Erich Klauke ,  Uwe Petersen ,  Klaus Grohe

IPC: C07C17/14 ,  C07C17/16 ,  C07C33/46 ,  C07C45/29 ,  C07C45/43 ,  C07C47/55 ,  C07C51/04 ,  C07C63/70 ,  C07C255/49 ,  C07D215/56 ,  C07D401/04 ,  C07D413/04 ,  C07C51/363 ,  C07C51/58 ,  C07C51/62

CPC classification number: C07D215/56 ,  C07C17/14 ,  C07C17/16 ,  C07C255/00 ,  C07C33/46 ,  C07C45/292 ,  C07C45/43 ,  C07C47/55 ,  C07C63/70 ,  C07D401/04 ,  C07D413/04

Abstract: 2,4,5-Trihalogenobenzene derivatives of the formula ##STR1## in which R is --COOH, --COCl, --COF, --CN, --CONH.sub.2, --CH.sub.2 OH, --CH.sub.2 Cl, --CHCl.sub.2, --CCl.sub.3 or --CHO,R.sup.1 is H, Cl or F, andR.sup.2 is Cl or F,it only being possible for R.sup.1 or R.sup.2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone carboxylic acids.

Abstract translation: 其中R是-COOH，-COCl，-COF，-CN，-CONH 2，-CH 2 OH，-CH 2 Cl，-CHCl 2，-CCl 3或-CHO的式“IMAGE”的2,4,5-三卤代苯衍生物，R1是 H，Cl或F，R2为Cl或F，只有R1或R2可能为F，并且从与氟化钾反应的苯甲腈开始制备它们的制备方法。 新型化合物是抗菌剂如喹诺酮羧酸的中间体。

公开(公告)号：US5200548A

公开(公告)日：1993-04-06

申请号：US763027

申请日：1991-09-20

Applicant: Erich Klauke ,  Uwe Petersen ,  Klaus Grohe

Inventor： Erich Klauke ,  Uwe Petersen ,  Klaus Grohe

IPC: C07C17/14 ,  C07C17/16 ,  C07C33/46 ,  C07C45/29 ,  C07C45/43 ,  C07C47/55 ,  C07C51/04 ,  C07C63/70 ,  C07C255/49 ,  C07D215/56 ,  C07D401/04 ,  C07D413/04

CPC classification number: C07D215/56 ,  C07C17/14 ,  C07C17/16 ,  C07C255/00 ,  C07C33/46 ,  C07C45/292 ,  C07C45/43 ,  C07C47/55 ,  C07C63/70 ,  C07D401/04 ,  C07D413/04

Abstract: 2,4,5-Trihalogenobenzene derivatives of the formula ##STR1## in which R is --COOH, --COCl, --COF, --CN, --CONH.sub.2, --CH.sub.2 OH, --CH.sub.2 Cl, --CHCl.sub.2, --CCl.sub.3 or --CHO,R.sup.1 is H, Cl or F, andR.sup.2 is Cl or F,it only being possible for R.sup.1 or R.sup.2 to be F, and processes for their preparation starting from benzonitriles reacted with potassium fluoride. The novel compounds are intermediates for antibacterials such as quinolone caboxylic acids.

Abstract translation: 其中R是-COOH，-COCl，-COF，-CN，-CONH 2，-CH 2 OH，-CH 2 Cl，-CHCl 2，-CCl 3或-CHO的式“IMAGE”的2,4,5-三卤代苯衍生物，R1是 H，Cl或F，R2为Cl或F，只有R1或R2可能为F，并且从与氟化钾反应的苯甲腈开始制备它们的制备方法。 这些新化合物是抗菌药物如喹诺酮木糖酸的中间体。

公开(公告)号：US4877443A

公开(公告)日：1989-10-31

申请号：US2881

申请日：1987-01-13

Applicant: Michael Schwamborn ,  Erich Klauke ,  Robert R. Schmidt ,  Hans-Joachim Santel ,  Robert H. Strang

Inventor： Michael Schwamborn ,  Erich Klauke ,  Robert R. Schmidt ,  Hans-Joachim Santel ,  Robert H. Strang

IPC: A01N43/54 ,  C07D239/48

CPC classification number: C07D239/48 ,  A01N43/54

Abstract: Herbicidally active 2,4-diamino-6-haloalkylpyrimidines of the formula ##STR1## in which R.sup.1 and R.sup.3, independently of one another, represent hydrogen or alkyl,R.sup.2 and R.sup.4, independently of one another, represent hydrogen, alkyl which is optionally substituted by halogen, cyano, alkoxy, alkylthio or by cyclopropyl, represent cycloalkyl, alkenyl which is optionally substituted by halogen, or alkinyl, andR.sup.5 represents alkyl which is substituted by halogen, with the proviso that R.sup.1, R.sup.2, R.sup.3 andR.sup.4 do not simultaneously represent hydrogen whenR.sup.5 represents trichloromethyl, and with the provisio that R.sup.1 and R.sup.2 do not simultaneously represent hydrogen when R.sup.4 represents alkyl which is substituted by alkoxy or alkylthio.

Abstract translation: R1和R3彼此独立地代表氢或烷基，R2和R4彼此独立的除草活性的2,4-二氨基-6-卤代烷基嘧啶，其中R 1和R 3彼此独立地代表氢，任选被取代的烷基 卤素，氰基，烷氧基，烷硫基或环丙基代表环烷基，任选被卤素或炔基取代的烯基，R 5表示被卤素取代的烷基，条件是R1，R2，R3和R4不同时 当R5表示三氯甲基时表示氢，当R 4表示被烷氧基或烷硫基取代的烷基时，R1和R2不同时表示氢。