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公开(公告)号：US10775307B2
公开(公告)日：2020-09-15
申请号：US16268663
申请日：2019-02-06
申请人： Enplas Corporation
发明人： Ken Kitamoto , Koichi Ono
摘要： This detection device is provided with: a chip including a detection region for detecting a substance to be detected; a light source which emits excitation light; a detector for detecting the fluorescence emitted from a fluorescent substance which labels the substance to be detected, and which is excited by the excitation light; and an optical fiber which includes a core, and a cladding covering the outer peripheral surface of the core, guides, to the detection region, the excitation light emitted from the light source, and guides, to the detector, the fluorescence emitted from the fluorescent substance. The optical fiber is fixed to the chip directly or via a connector. The excitation light emitted from the light source is guided within the core, and reaches the detection region of the chip. The fluorescence emitted from the fluorescent substance is guided within the core and the cladding, and reaches the detector.
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公开(公告)号：US09101932B2
公开(公告)日：2015-08-11
申请号：US14031941
申请日：2013-09-19
申请人： Enplas Corporation
发明人： Koichi Ono
IPC分类号： B01L3/00 , G01N27/00 , G01N27/447 , G01N27/26 , G01N33/00
CPC分类号： B01L3/502715 , B01L2200/027 , B01L2200/10 , B01L2300/0645 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2300/1827 , B01L2400/0415 , B01L2400/0421 , G01N27/44791
摘要： Microchannel chip (100) has film (120) adhered on the second surface of base (110) having a through-hole (111), and conductive layer (130). Film (120) has hole (121) and covers a second opening of the through-hole (111). Conductive layer (130) is integrally formed so as to extend from a portion of a bottom of hole (121) of base (110) to a portion of an inner surface of through-hole (111). Upon comparison with a microchannel chip in the related art, microchannel chip (100) is further reduced in size, has excellent handleability and is easy to be manufactured.
摘要翻译： 微通道芯片（100）具有粘附在具有通孔（111）和导电层（130）的基体（110）的第二表面上的膜（120）。 膜（120）具有孔（121）并覆盖通孔（111）的第二开口。 导电层（130）一体地形成为从底座（110）的孔（121）的底部的一部分延伸到通孔（111）的内表面的一部分。 与现有技术的微通道芯片进行比较，微通道芯片（100）的尺寸进一步降低，易于操作，易于制造。
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公开(公告)号：US10458572B2
公开(公告)日：2019-10-29
申请号：US15526498
申请日：2015-10-29
申请人： Enplas Corporation
发明人： Ken Kitamoto , Koichi Ono
摘要： A liquid handling device has an accommodation part for accommodating a liquid, two or more flow paths each opening to a lower part of a side wall surface of the accommodation part, and a liquid movement suppression part that is disposed in the lower part of the side wall between the openings of two of the flow paths that are adjacent to each other and slows or stops the movement of the liquid along the corner formed by the lower surface of the accommodation part and the side wall surface.
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公开(公告)号：US10241049B2
公开(公告)日：2019-03-26
申请号：US15120025
申请日：2015-02-16
申请人： Enplas Corporation
发明人： Ken Kitamoto , Koichi Ono
摘要： This detection device is provided with: a chip including a detection region for detecting a substance to be detected; a light source which emits excitation light; a detector for detecting the fluorescence emitted from a fluorescent substance which labels the substance to be detected, and which is excited by the excitation light; and an optical fiber which includes a core, and a cladding covering the outer peripheral surface of the core, guides, to the detection region, the excitation light emitted from the light source, and guides, to the detector, the fluorescence emitted from the fluorescent substance. The optical fiber is fixed to the chip directly or via a connector. The excitation light emitted from the light source is guided within the core, and reaches the detection region of the chip. The fluorescence emitted from the fluorescent substance is guided within the core and the cladding, and reaches the detector.
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公开(公告)号：US09463459B2
公开(公告)日：2016-10-11
申请号：US14990826
申请日：2016-01-08
申请人： Enplas Corporation
发明人： Koichi Ono
CPC分类号： B01L3/502738 , B01J19/00 , B01L3/502707 , B01L2300/0816 , B01L2300/0858 , B01L2300/0861 , B01L2300/12 , B01L2300/123 , B01L2400/0487 , B01L2400/0655 , F16K7/17 , F16K99/0015 , F16K99/0059 , F16K2099/008 , G01N1/10
摘要： A fluid handling device has a first substrate, a second substrate, and a resin film disposed between the first substrate and the second substrate. The first substrate includes a first channel, a valve body facing area having a substantially circular segment-shaped opening, a second channel, and a partition wall formed between the valve body facing area and an end on one side of the second channel. The second substrate includes a pressure chamber. The resin film includes a substantially spherical cap-shaped diaphragm portion. A radius of an outer edge of the diaphragm portion is smaller than a radius of a circular arc of the valve body facing area. The diaphragm portion is so arranged as to straddle the valve body facing area and the end on one side of the second channel.
摘要翻译： 流体处理装置具有第一基板，第二基板和设置在第一基板和第二基板之间的树脂膜。 第一基板包括第一通道，具有基本上圆形的段状开口的阀体相对的区域，第二通道，以及形成在阀体相对区域与第二通道的一侧的端部之间的分隔壁。 第二基板包括压力室。 树脂膜包括大致球形的帽状隔膜部分。 隔膜部分的外边缘的半径小于阀体相对面积的圆弧的半径。 隔膜部分被布置成跨越第二通道的一侧的阀体相对区域和端部。
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公开(公告)号：US11666904B2
公开(公告)日：2023-06-06
申请号：US17387149
申请日：2021-07-28
申请人： Enplas Corporation
发明人： Koichi Ono , Hayato Inoue , Tomoki Nakao , Seiichiro Suzuki
IPC分类号： B01L3/00
CPC分类号： B01L3/502707 , B01L3/502746 , B01L2200/0689 , B01L2300/123
摘要： A fluid handling system includes a fluid handling device including an opening for introducing a fluid or discharging the fluid; a tube including a flange, where one end of the tube is for connection to the opening, and the other end of the tube is for connection to an introduction device for supplying the fluid or to a discharge device for discharging the fluid; a support member including a first through hole into which the tube is inserted, and movably supporting the tube; and a first elastic member including a second through hole into which the tube is inserted, and holding a part of the tube while the first elastic member is in contact with the flange and the fluid handling device or the support member.
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公开(公告)号：US10830362B2
公开(公告)日：2020-11-10
申请号：US16324179
申请日：2017-08-03
申请人： Enplas Corporation
发明人： Koichi Ono , Nobuya Sunaga
摘要： This fluid handling device has a substrate, a film, and a sliding member. The substrate has first flow paths, second flow paths, and partition walls formed between one end of the first flow paths and one end of the second flow paths. The film includes a diaphragm, and is arranged above the substrate such that the diaphragm and the partition walls oppose one another. The sliding member has protrusions formed on the back surface thereof, and is arranged above the film with the back surface facing the film. By sliding on the film the sliding member is able switch alternately between a first state in which the protrusions are arranged so as not to oppose the partition walls, and the diaphragm is sandwiched therebetween, and a second state in which the protrusions are arranged opposing the partition walls, and the diaphragm is sandwiched therebetween.
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公开(公告)号：US09387477B2
公开(公告)日：2016-07-12
申请号：US14731491
申请日：2015-06-05
申请人： Enplas Corporation
发明人： Koichi Ono , Ken Kitamoto
CPC分类号： B01L3/502715 , B01L3/502707 , B01L2200/0689 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0887 , B01L2300/123 , B01L2300/16 , B01L2300/18 , B01L2300/1827 , B01L2400/0406
摘要： A fluid handling device includes a substrate, a film and a conductive layer. The substrate includes a through hole or a recess. The film includes first, second and third regions. The conductive layer is disposed on one surface of the film across the first, second and third regions. The first region of the film is bonded to one surface of the substrate such that one of openings of the through hole or an opening of the recess is closed to form a housing part, and that a part of the conductive layer is exposed to the inside of the housing part. The second region of the film is bent such that the conductive layer is located on an outside. The third region of the film is bonded to the first region of the film such that the conductive layer is exposed to the exterior.
摘要翻译： 流体处理装置包括基板，膜和导电层。 基板包括通孔或凹槽。 这部电影包括第一，第二和第三个地区。 导电层设置在膜的跨越第一，第二和第三区域的一个表面上。 膜的第一区域被粘合到基板的一个表面上，使得通孔的开口或凹部的开口中的一个闭合以形成壳体部分，并且导电层的一部分暴露于内部 的房屋部分。 薄膜的第二区域弯曲，使得导电层位于外部。 膜的第三区域被粘合到膜的第一区域，使得导电层暴露于外部。
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公开(公告)号：US09283558B2
公开(公告)日：2016-03-15
申请号：US14722604
申请日：2015-05-27
申请人： Enplas Corporation
发明人： Koichi Ono , Ken Kitamoto
CPC分类号： B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L2200/0689 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/1827
摘要： A fluid handling device includes a substrate, a film, and a conductive layer. The substrate includes a first through-hole, and a second through-hole. The conductive layer is disposed on one surface of the film to extend in a first area, a second area and a third area of the film. The substrate includes a first surface and a second surface facing away from the first surface. The first area is bonded to the first surface of the substrate such that a housing part is formed by closing one opening of the first through-hole, and such that a part of the conductive layer is exposed to the inside of the housing part. The second area is disposed inside the second through-hole, and the third area is bonded to the second surface of the substrate such that a part of the conductive layer is exposed to the outside.
摘要翻译： 流体处理装置包括基板，膜和导电层。 基板包括第一通孔和第二通孔。 导电层设置在膜的一个表面上，以在膜的第一区域，第二区域和第三区域中延伸。 基板包括第一表面和背离第一表面的第二表面。 第一区域结合到基板的第一表面，使得通过闭合第一通孔的一个开口形成壳体部分，并且使得导电层的一部分暴露于壳体部分的内部。 第二区域设置在第二通孔的内部，并且第三区域结合到基板的第二表面，使得导电层的一部分暴露于外部。
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公开(公告)号：US11268620B2
公开(公告)日：2022-03-08
申请号：US17061237
申请日：2020-10-01
申请人： Enplas Corporation
发明人： Koichi Ono , Nobuya Sunaga
摘要： A channel chip having a channel for running a fluid that is opened and closed by sliding on a film a sliding member slidable on the film while contacting with the film, the channel chip comprising: a substrate including a first channel, a second channel and a partition wall formed between the first channel and the second channel; a film including a diaphragm having a substantially spherical crown shape, the film being disposed on the substrate so that the diaphragm faces the partition wall; and a positioning section for holding the sliding member in such a way that the sliding member is slidable on the film while the positioning section positions the sliding member, the positioning section being disposed on the film.
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