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公开(公告)号:US20120196874A1
公开(公告)日:2012-08-02
申请号:US13360109
申请日:2012-01-27
申请人: David WATT , Chunming Liu , Vitaliy M. Sviripa , Wen Zhang
发明人: David WATT , Chunming Liu , Vitaliy M. Sviripa , Wen Zhang
IPC分类号: A61K31/05 , C07C43/23 , A61K31/09 , C07C291/04 , A61K31/136 , C07C211/52 , C07D495/04 , A61K31/4188 , C07D295/073 , A61K31/495 , C07D233/64 , A61K31/4164 , A61P35/00 , G01N33/53 , G01N33/566 , C12Q1/68 , C07C39/21
CPC分类号: A61K31/03 , A61K31/44 , C07C39/21 , C07C43/23 , C07C211/48 , C07C211/52 , C07C291/04 , C07D233/64 , C07D295/073 , C07D495/04 , C09B23/148 , G01N33/57484 , G01N33/582 , G01N2800/52
摘要: Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. The halogenated stilbene analogs include nitrogen heteroaryl groups and/or amino groups on the stilbene ring.
摘要翻译: 公开了可用于治疗各种癌症的芪类似物和药物组合物,包括但不限于结肠直肠癌(CRC)和乳腺癌。 卤化1,2-二苯乙烯类似物包括二苯乙烯环上的氮杂芳基和/或氨基。
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公开(公告)号:US08664276B2
公开(公告)日:2014-03-04
申请号:US13360109
申请日:2012-01-27
申请人: David Watt , Chunming Liu , Vitaliy M. Sviripa , Wen Zhang
发明人: David Watt , Chunming Liu , Vitaliy M. Sviripa , Wen Zhang
IPC分类号: A61K31/136 , C07C211/45
CPC分类号: A61K31/03 , A61K31/44 , C07C39/21 , C07C43/23 , C07C211/48 , C07C211/52 , C07C291/04 , C07D233/64 , C07D295/073 , C07D495/04 , C09B23/148 , G01N33/57484 , G01N33/582 , G01N2800/52
摘要: Stilbene analogs and pharmaceutical compositions that are useful for the treatment of various cancers, including without limitation, colorectal cancer (CRC) and breast cancer are disclosed. Such stilbene analogs include, for example, compounds of the following formula: wherein Ra, Rb, R4, R6, R7, R9 and R10 are all H; R2 and R3 are independently H, halo, amino, alkylamino, dialkylamino, N-oxides of dialkylamino, arylalkylamino, trialkylammonium, mercapto, alkylthio, alkanoyl, nitro, nitrosyl, cyano, alkoxy, alkenyloxy, aryl, heteroaryl, sulfonyl, sulfonamide, CONR11R12, NR11CO(R13), NR11COO(R13) or NR11CONR12R13; R11, R12 and R13, are independently, H, alkyl, aryl, heteroaryl or a fluorine; R8 is NRCRdZ wherein Rc is H, alkyl, alkoxy, aryl or heteroaryl, Rd is an alkyl group, Z is a an unshared pair of electrons, H, alkyl or oxygen; and R1 and R5 are halogen.
摘要翻译: 公开了可用于治疗各种癌症的芪类似物和药物组合物,包括但不限于结肠直肠癌(CRC)和乳腺癌。 这样的1,2-二苯乙烯类似物包括例如下式的化合物:其中R a,R b,R 4,R 6,R 7,R 9和R 10均为H; R2和R3独立地是H,卤素,氨基,烷基氨基,二烷基氨基,二烷基氨基,芳基烷基氨基,三烷基铵,巯基,烷硫基,烷酰基,硝基,亚硝酰基,氰基,烷氧基,烯氧基,芳基,杂芳基,磺酰基,磺酰胺,CONR11R12 ,NR 11 CO(R 13),NR 11 COO(R 13)或NR 11 CONR 12 R 13; R 11,R 12和R 13独立地为H,烷基,芳基,杂芳基或氟; R8是NRCRdZ,其中Rc是H,烷基,烷氧基,芳基或杂芳基,Rd是烷基,Z是未共享的电子对,H,烷基或氧; 并且R 1和R 5是卤素。
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公开(公告)号:US08699417B2
公开(公告)日:2014-04-15
申请号:US13155336
申请日:2011-06-07
申请人: Chunming Liu , Christopher Lawrence
发明人: Chunming Liu , Christopher Lawrence
CPC分类号: H04W40/12 , H04L45/121 , H04L45/50
摘要: Described herein are techniques related to wireless communication systems that may implement microwave backhaul for connectivity between network elements deployed by the wireless communication systems. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译: 这里描述的是与无线通信系统相关的技术,其可以实现用于由无线通信系统部署的网络元件之间的连接的微波回程。 提交本摘要的理解是,它不会用于解释或限制权利要求的范围或含义。
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公开(公告)号:US20120275342A1
公开(公告)日:2012-11-01
申请号:US13155340
申请日:2011-06-07
IPC分类号: H04W40/12
CPC分类号: H04W40/12 , H04L45/121 , H04L45/50
摘要: Described herein are techniques related to wireless communication systems that may implement microwave backhaul for connectivity between network elements deployed by the wireless communication systems. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译: 这里描述的是与无线通信系统相关的技术,其可以实现用于由无线通信系统部署的网络元件之间的连接的微波回程。 提交本摘要的理解是,它不会用于解释或限制权利要求的范围或含义。
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公开(公告)号:US20150078207A1
公开(公告)日:2015-03-19
申请号:US14552286
申请日:2014-11-24
申请人: Chunming Liu , Christopher Lawrence
发明人: Chunming Liu , Christopher Lawrence
IPC分类号: H04W40/12
CPC分类号: H04W40/12 , H04L45/121 , H04L45/50
摘要: Described herein are techniques related to wireless communication systems that may implement microwave backhaul for connectivity between network elements deployed by the wireless communication systems. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
摘要翻译: 这里描述的是与无线通信系统相关的技术,其可以实现用于由无线通信系统部署的网络元件之间的连接的微波回程。 提交本摘要的理解是,它不会用于解释或限制权利要求的范围或含义。
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公开(公告)号:US08897173B2
公开(公告)日:2014-11-25
申请号:US13155340
申请日:2011-06-07
申请人: Chunming Liu , Christopher Lawrence
发明人: Chunming Liu , Christopher Lawrence
IPC分类号: H04L12/28 , H04W40/12 , H04L12/727 , H04L12/723
CPC分类号: H04W40/12 , H04L45/121 , H04L45/50
摘要: Described herein are techniques related to wireless communication systems that may implement microwave backhaul for connectivity between network elements deployed by the wireless communication systems. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
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公开(公告)号:US08849331B2
公开(公告)日:2014-09-30
申请号:US13587749
申请日:2012-08-16
申请人: Chunming Liu , Christopher Lawrence
发明人: Chunming Liu , Christopher Lawrence
CPC分类号: H04W52/02 , H04W52/0235 , H04W72/1247 , Y02D70/122 , Y02D70/1242 , Y02D70/1262 , Y02D70/146 , Y02D70/23
摘要: Techniques for allocating network resources of a communications network are described. A network resource scheduler allocates communication bursts to telecommunications devices in a manner so as to conserve power of the mobile telecommunication devices. The network resource scheduler may allocate communication bursts such that at least one of the mobile telecommunication devices may enter sleep mode during a current communications block and be awoken prior to a subsequent communications block.
摘要翻译: 描述了用于分配通信网络的网络资源的技术。 网络资源调度器以通信方式分配通信突发以便节省移动电信设备的功率。 网络资源调度器可以分配通信突发,使得移动电信设备中的至少一个可以在当前通信块期间进入睡眠模式,并且在随后的通信块之前唤醒。
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公开(公告)号:US20130217428A1
公开(公告)日:2013-08-22
申请号:US13587749
申请日:2012-08-16
申请人: Chunming Liu , Christopher Lawrence
发明人: Chunming Liu , Christopher Lawrence
IPC分类号: H04W52/02
CPC分类号: H04W52/02 , H04W52/0235 , H04W72/1247 , Y02D70/122 , Y02D70/1242 , Y02D70/1262 , Y02D70/146 , Y02D70/23
摘要: Techniques for allocating network resources of a communications network are described. A network resource scheduler allocates communication bursts to telecommunications devices in a manner so as to conserve power of the mobile telecommunication devices. The network resource scheduler may allocate communication bursts such that at least one of the mobile telecommunication devices may enter sleep mode during a current communications block and be awoken prior to a subsequent communications block.
摘要翻译: 描述了用于分配通信网络的网络资源的技术。 网络资源调度器以通信方式分配通信突发以便节省移动电信设备的功率。 网络资源调度器可以分配通信突发,使得移动电信设备中的至少一个可以在当前通信块期间进入睡眠模式,并且在随后的通信块之前唤醒。
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公开(公告)号:US20120275375A1
公开(公告)日:2012-11-01
申请号:US13155336
申请日:2011-06-07
IPC分类号: H04W40/00
CPC分类号: H04W40/12 , H04L45/121 , H04L45/50
摘要: Described herein are techniques related to wireless communication systems that may implement microwave backhaul for connectivity between network elements deployed by the wireless communication systems. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
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