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    Antimicrobial substrates with peroxide treatment
    1.
    发明申请
    Antimicrobial substrates with peroxide treatment 审中-公开
    用过氧化物处理的抗微生物底物

    公开(公告)号：US20070134302A1

    公开(公告)日：2007-06-14

    申请号：US11301546

    申请日：2005-12-13

    Applicant: David Koenig ,  Ali Yahiaoui ,  Alison Bagwell

    Inventor： David Koenig ,  Ali Yahiaoui ,  Alison Bagwell

    IPC: A61K9/70 ,  A61K33/40

    CPC classification number: A61K33/40 ,  A01N25/34 ,  A61L2/23 ,  A61L2/232 ,  A01N59/00 ,  A01N33/12 ,  A01N25/22 ,  A01N25/10

    Abstract: An oxidizing antimicrobial treatment and products containing such treatment are described. The treatment involve, in part, preparing a substrate to accept an attachment of charged moieties, and a number of stabilized peroxide compounds on at least part of a surface of said substrate. When microbes, such as bacteria, having a net charge opposite to that of the charged moieties come in close proximity to the treated substrate surface, peroxide molecules from the substrate are activated and released to kill the microbes.

    Abstract translation: 描述了氧化性抗微生物处理和含有这种处理的产品。 该处理部分地涉及制备底物以接受带电部分的附着物，以及在所述基材的至少部分表面上的多种稳定的过氧化物化合物。 当具有与带电部分的净电荷相反的净电荷的微生物与处理的底物表面紧密接近时，来自底物的过氧化物分子被活化并释放以杀死微生物。

    Application of an antimicrobial agent on an elastomeric article
    2.
    发明申请
    Application of an antimicrobial agent on an elastomeric article 审中-公开
    抗微生物剂在弹性制品上的应用

    公开(公告)号：US20060140994A1

    公开(公告)日：2006-06-29

    申请号：US11023201

    申请日：2004-12-27

    Applicant: Alison Bagwell ,  David Koenig ,  Martin Shamis ,  Jali Williams

    Inventor： Alison Bagwell ,  David Koenig ,  Martin Shamis ,  Jali Williams

    IPC: A01N25/34

    CPC classification number: C08J7/065 ,  C08J5/02 ,  C08J2321/02

    Abstract: An elastomeric article having reducing microbe affinity and transmission and methods for applying and immobilizing antimicrobial compounds to the elastomeric substrate surface are disclosed. The elastomeric article has a body formed of a natural or synthetic polymer latex having an outer surface and an inner surface. The body has a coating of an antimicrobial agent over at least a portion of said outer surface. The treatment involves applying according to either a spraying or dipping process an antimicrobial polymer or composition to a surface of the elastomeric substrate; binding the antimicrobial composition to the surface in a manner such that said treat antimicrobial coating passes either one or another or both versions of a zone of inhibition test, such test including: a) a dry-leaching or agar-plate-based contact test, according to AATCC 147 protocol, or b) a wet-leaching or dynamic shake flask test according to ASTM E-2149-01 protocol. The substrate is further subject to a rapid germicidal contact-transfer test of relatively short duration. The antimicrobial polymer can include an organosilane quaternary ammonium or a biguanide compound which can disrupt the ionic charges of microbial cellular membranes.

    Abstract translation: 公开了具有降低的微生物亲和性和透射性的弹性制品以及将抗微生物化合物施加和固定到弹性体基底表面上的方法。 弹性制品具有由具有外表面和内表面的天然或合成聚合物胶乳形成的本体。 身体在所述外表面的至少一部分上具有抗微生物剂的涂层。 该处理包括根据喷雾或浸渍方法将抗微生物聚合物或组合物施用于弹性体基材的表面; 将抗微生物组合物以使得所述处理的抗微生物涂层通过抑制试验区的一种或两种或两种形式的方式将抗微生物组合物结合到表面，所述测试包括：a）干浸或琼脂平板接触试验， 根据AATCC 147方案，或b）根据ASTM E-2149-01方案的湿浸或动态摇瓶试验。 底物进一步经历相对较短持续时间的快速杀菌接触转移试验。 抗微生物聚合物可以包括可以破坏微生物细胞膜的离子电荷的有机硅烷季铵或双胍化合物。

    Non-leaching antimicrobial glove
    3.
    发明申请
    Non-leaching antimicrobial glove 审中-公开
    非浸出抗菌手套

    公开(公告)号：US20050147655A1

    公开(公告)日：2005-07-07

    申请号：US11057576

    申请日：2005-02-14

    Applicant: Alison Bagwell ,  David Johnson ,  David Koenig ,  Martin Shamis ,  Wava Truscott

    Inventor： Alison Bagwell ,  David Johnson ,  David Koenig ,  Martin Shamis ,  Wava Truscott

    IPC: A41D19/00 ,  A61B19/04 ,  C08J7/04 ,  B32B5/02 ,  A61K9/70

    CPC classification number: C08J7/047 ,  A41D19/0058 ,  A41D31/30 ,  A61B42/00 ,  C08J2321/00 ,  C08J2483/00 ,  Y10T428/31663 ,  Y10T442/2525

    Abstract: An elastomeric article having reducing microbe affinity and transmission is disclosed. The article has a coating of a hydrophobic, non-leaching antimicrobial polymer that is durably attached to an exterior surface, such that said antimicrobial polymer does not spontaneously migrate or is not removed from said exterior surface in the presence of aqueous substances, strong acids and bases, and organic solvents, and said antimicrobial polymer forms either a water-insoluable siloxane resin, or a covalently attached siloxane homopolymer, or a combination of both. The coated surface has a reduced affinity for aqueous-based substances and exhibits an enduring reduction in microbe affinity and transmission.

    Abstract translation: 公开了具有降低的微生物亲和性和透射性的弹性制品。 所述制品具有耐久地连接到外表面的疏水性非浸出抗微生物聚合物的涂层，使得所述抗微生物聚合物在水性物质，强酸和强酸存在下不会自发迁移或不从所述外表面除去， 碱和有机溶剂，并且所述抗微生物聚合物形成水不溶性硅氧烷树脂或共价连接的硅氧烷均聚物或两者的组合。 涂覆的表面对水基物质的亲和力降低，并显示出微生物亲和力和透射性的持续降低。

    Antimicrobial composition
    4.
    发明申请
    Antimicrobial composition 审中-公开
    抗微生物组成

    公开(公告)号：US20070048344A1

    公开(公告)日：2007-03-01

    申请号：US11216800

    申请日：2005-08-31

    Applicant: Ali Yahiaoui ,  Phillip Schorr ,  Douglas Hoffman ,  David Koenig ,  Anthony Spencer ,  Angela Dobson

    Inventor： Ali Yahiaoui ,  Phillip Schorr ,  Douglas Hoffman ,  David Koenig ,  Anthony Spencer ,  Angela Dobson

    IPC: A01N57/00 ,  A01N43/80 ,  A01N25/00 ,  A01N43/04

    CPC classification number: C08K5/0058 ,  C08K5/31

    Abstract: An antimicrobial composition that involves a synergistic mixture in terms of active agents, of a primary antimicrobial agent, such as polyhexamethylene biguanide (PHMB), a secondary antimicrobial agent, and optionally an organic acid against various kinds of microbes is described. Various additional processing aids, such as alcohols and surfactants, may also be incorporated within the mixture. The composition allows one to use a significantly less concentration of individual constituent antimicrobial agents to achieve the same or a better degree of antimicrobial efficacy. The antimicrobial composition can be applied to the surface of almost any kind of substrate material, and can achieve a killing-efficacy of about 3 Log10 reduction in microbes within 30 minutes under ambient conditions.

    Abstract translation: 描述了关于活性剂，主要抗微生物剂如聚六亚甲基双胍（PHMB），二次抗微生物剂和任选的针对各种微生物的有机酸的协同混合物的抗微生物组合物。 各种其它加工助剂，如醇和表面活性剂，也可以掺入混合物中。 该组合物允许使用显着较少浓度的单个成分抗微生物剂以达到相同或更好程度的抗微生物效力。 抗微生物组合物可以应用于几乎任何种类的底物材料的表面，并且可以在环境条件下在30分钟内实现微生物中约3log 10/10的还原的杀伤效力。

    Absorbent articles comprising a bodily exudate modifying agent and a skin care formulation
    9.
    发明申请
    Absorbent articles comprising a bodily exudate modifying agent and a skin care formulation 有权
    包含身体渗出物改性剂和皮肤护理制剂的吸收制品

    公开(公告)号：US20060036222A1

    公开(公告)日：2006-02-16

    申请号：US10915642

    申请日：2004-08-10

    Applicant: Jason Cohen ,  David Koenig ,  Earl Brock ,  Stephen Baratian ,  Corey Cunningham ,  Stephen Baldwin

    Inventor： Jason Cohen ,  David Koenig ,  Earl Brock ,  Stephen Baratian ,  Corey Cunningham ,  Stephen Baldwin

    IPC: A61F13/15

    CPC classification number: A61L15/18 ,  A61L15/20 ,  A61L15/38

    Abstract: Absorbent articles having enhanced absorption of bodily exudates are disclosed. The absorbent articles comprise a bodily exudate modifying agent and a skin care formulation. The bodily exudate modifying agent is capable of reducing the viscosity of bodily exudates such as feces and menses. The skin care formulation comprises a bodily exudate modifying agent neutralizer to neutralize the possible negative effects on skin barrier function caused by the bodily exudate modifying agents coming into direct contact with the wearer's skin.

    Abstract translation: 公开了具有增强的身体渗出物吸收的吸收制品。 吸收制品包括身体渗出物改性剂和皮肤护理制剂。 身体渗出物改性剂能够降低诸如粪便和月经之类的身体渗出物的粘度。 皮肤护理制剂包括身体渗出物改性剂中和剂，以中和由与穿着者皮肤直接接触的身体渗出物改性剂引起的对皮肤屏障功能的可能的负面影响。

    Processes for controlling microbial organic compound production
    10.
    发明申请
    Processes for controlling microbial organic compound production 有权
    控制微生物有机化合物生产的过程

    公开(公告)号：US20050201968A1

    公开(公告)日：2005-09-15

    申请号：US11055503

    申请日：2005-02-10

    Applicant: David Koenig ,  Bernard Minerath ,  Lindsay Gould

    Inventor： David Koenig ,  Bernard Minerath ,  Lindsay Gould

    IPC: A61L15/20 ,  A61L15/46 ,  A61K7/06 ,  A61K7/11 ,  A61K33/40

    CPC classification number: A61L15/20 ,  A61L15/46 ,  A61L2300/11 ,  A61L2300/404 ,  A61L2300/622 ,  Y10S514/97

    Abstract: Processes for preparing products comprising an oxygen-generating additive for reducing the amount of skin irritation and inflamation and odor are disclosed. Specifically, products such as training pants and diapers are disclosed which contain a carbohydrate-hydrogen peroxide crystalline powder which, when wetted, produces a stream of oxygen which can be used by various bacteria on and near the wearer's skin during metabolism resulting in a significant decrease in the amount of volatile organic compounds produced by the bacteria during metabolism.

    Abstract translation: 公开了用于制备包含用于减少皮肤刺激和炎症和气味量的产氧添加剂的产品的方法。 具体地说，公开了诸如训练裤和尿布的产品，其中含有碳水化合物 - 过氧化氢结晶粉末，其在润湿时产生氧气流，其可以在代谢期间在佩戴者皮肤上和附近由各种细菌使用，从而导致显着降低 在代谢期间由细菌产生的挥发性有机化合物的量。

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