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    Distal assembly for a medical device
    1.
    发明授权
    Distal assembly for a medical device 有权
    医疗器械的远端组件

    公开(公告)号：US07747314B2

    公开(公告)日：2010-06-29

    申请号：US10748933

    申请日：2003-12-30

    申请人： David J. Parins ,  Peter Skujins

    发明人： David J. Parins ,  Peter Skujins

    IPC分类号： A61M25/00

    CPC分类号： A61M25/09 ,  A61M25/0068 ,  A61M2025/09083 ,  A61M2025/09108 ,  A61M2025/09175 ,  Y10T29/49826

    摘要： Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

    摘要翻译： 导线的替代设计，材料和制造方法。 一些实施例涉及具有近端和远端部分的复合导丝，以及适于和构造用于将近端部分永久地连接到远端部分的连接器。 在一些实施例中，至少一个部分由线性弹性镍钛合金制成。 还公开了包括卷绕的安全/成形结构的几种替代的导线尖端设计。

    COMPOSITE GUIDEWIRE
    2.
    发明申请
    COMPOSITE GUIDEWIRE 有权
    复合指南

    公开(公告)号：US20070244414A1

    公开(公告)日：2007-10-18

    申请号：US11763973

    申请日：2007-06-15

    申请人： Brian Reynolds ,  Peter Skujins ,  Brice Shireman ,  Bruce Asmus ,  Ron Tanaka ,  Michael Swee

    发明人： Brian Reynolds ,  Peter Skujins ,  Brice Shireman ,  Bruce Asmus ,  Ron Tanaka ,  Michael Swee

    IPC分类号： A61M25/01

    CPC分类号： A61M25/0905 ,  A61L31/022 ,  A61M25/09 ,  A61M2025/09141 ,  A61M2025/09175

    摘要： Alternative designs, materials and manufacturing methods for guidewires. Some embodiments pertain to a composite guidewire having proximal and distal section, and a connector adapted and configured for permanently joining the proximal section to the distal section. In some embodiments, at least one of the sections is made of a linear-elastic nickel-titanium alloy. Several alternative guidewire tip designs including coiled safety/shaping structures are also disclosed.

    摘要翻译： 导线的替代设计，材料和制造方法。 一些实施例涉及具有近端和远端部分的复合导丝，以及适于和构造用于将近端部分永久地连接到远端部分的连接器。 在一些实施例中，至少一个部分由线性弹性镍钛合金制成。 还公开了包括卷绕的安全/成形结构的几种替代的导线尖端设计。

    Elongated medical device for intracorporal use
    3.
    发明授权
    Elongated medical device for intracorporal use 失效
    长期使用的医疗器械

    公开(公告)号：US07237313B2

    公开(公告)日：2007-07-03

    申请号：US10729076

    申请日：2003-12-05

    申请人： Peter Skujins ,  Brian R. Reynolds

    发明人： Peter Skujins ,  Brian R. Reynolds

    IPC分类号： B23P11/00

    CPC分类号： A61M25/09 ,  A61M2025/09083 ,  A61M2025/09108 ,  A61M2025/09141 ,  A61M2025/09166 ,  A61M2025/09175 ,  Y10T29/49826 ,  Y10T29/49908 ,  Y10T29/49929 ,  Y10T29/49947 ,  Y10T29/49966 ,  Y10T29/49968 ,  Y10T403/49 ,  Y10T403/4949 ,  Y10T403/4966

    摘要： Alternative designs, materials and manufacturing methods for medical devices. Some embodiments disclosed deal with attachment of an elongated structure, such as a wire or ribbon, or a tubular member, such as a coil, to an elongated member in an elongated device. For example, an elongated core member having defining an outer surface, and an elongated structure including a first portion and a second expanded portion along the length thereof can be provided. An attachment member, such as a centering ring, or the like, is disposed about a portion of the elongated core member and a part of the first portion of the elongated structure. The attachment member defines a lumen and having an inner surface. Part of the first portion of the elongated structure is disposed between the inner surface of the attachment member and the outer surface of the elongated core member. A part of the second portion of the elongated structure is in mechanical engagement with the inner surface of the attachment member and the outer surface the elongated core member to provide a mechanical coupling of the elongated structure between the attachment member and the elongated core member. Some embodiments provide a method of making such a construction, wherein the elongated structure can be moved relative to the attachment member such that the second portion of the elongated structure engages the inner surface of the attachment member and the outer surface the elongated core member to mechanically couple the elongated structure to the elongated core member.

    摘要翻译： 医疗器械的替代设计，材料和制造方法。 所公开的一些实施例涉及细长结构（例如线或带）或管状构件（例如线圈）与细长装置中的细长构件的连接。 例如，可以提供限定外表面的细长芯部件，以及沿其长度包括第一部分和第二扩张部分的细长结构。 诸如定心环等的附接构件围绕细长芯构件的一部分和细长结构的第一部分的一部分设置。 附接构件限定内腔并具有内表面。 细长结构的第一部分的一部分设置在附接构件的内表面和细长芯构件的外表面之间。 细长结构的第二部分的一部分与附接构件的内表面和外表面与细长芯构件机械接合，以提供细长结构在附接构件与细长芯构件之间的机械联接。 一些实施例提供了制造这种结构的方法，其中细长结构可以相对于附接构件移动，使得细长结构的第二部分与附接构件的内表面和外表面细长的芯构件接合以机械地 将细长结构连接到细长的芯部件上。

    Moisture curable polyurethane systems
    7.
    发明授权
    Moisture curable polyurethane systems 失效
    水分可固化聚氨酯系统

    公开(公告)号：US4038239A

    公开(公告)日：1977-07-26

    申请号：US605910

    申请日：1975-08-19

    申请人： Robert N. Coyner ,  Peter Skujins

    发明人： Robert N. Coyner ,  Peter Skujins

    IPC分类号： C08G18/08 ,  C08G18/70

    CPC分类号： C08G18/0885

    摘要： The disclosed process for making a high % solids, one-part, curable, essentially flowable or pumpable, high equivalent weight polyurethane (i.e., polyol-polyisocyanate adduct) prepolymer composition involves de-watering the polyol component of the reaction mixture with an alkaline earth metal oxide, preferably calcium oxide; adding the minimum acceptable level of catalyst for the NCO/polyol reaction; exothermically reacting a partially hindered aliphatic polyisocyanate such as isophorone diisocyanate (IPDI) and a partially hindered aromatic polyisocyanate such as 2,4-tolylene diisocyanate seriatim, so that at least about one-fourth of the IPDI reacts before the 2,4-TDI is added; and then adding more catalyst for the curing (e.g. moisture cure) reaction. Careful control over the amounts and selection of raw materials, proper selection of sequences of addition of these amounts and materials, careful de-watering of the reaction mixture, and proper adjustment or selection of isocyanate functionality minimizes random and undesired reactions and side reactions (e.g. chain extension) during prepolymer formation and insures good elastomeric properties in the ultimately cured product. As a result, this well-controlled prepolymer composition can be made efficiently with simple mixing equipment. One of the preferred coating or sealant uses for the prepolymer product is cured elastomeric coatings for the building industry, e.g. as a primary seal in roofing.

    METHOD AND APPARATUS FOR INTRAVASCULAR IMAGING AND OCCLUSION CROSSING
    9.
    发明申请
    METHOD AND APPARATUS FOR INTRAVASCULAR IMAGING AND OCCLUSION CROSSING 审中-公开
    方法和装置用于血管成像和闭塞穿刺

    公开(公告)号：US20090131798A1

    公开(公告)日：2009-05-21

    申请号：US12273593

    申请日：2008-11-19

    申请人： Christopher D. Minar ,  Peter Skujins ,  Raju R. Viswanathan ,  Guy Besson ,  Gareth T. Munger

    发明人： Christopher D. Minar ,  Peter Skujins ,  Raju R. Viswanathan ,  Guy Besson ,  Gareth T. Munger

    IPC分类号： A61B8/14 ,  A61B18/14 ,  A61M25/01

    CPC分类号： A61B8/4461 ,  A61B5/02007 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/445 ,  A61B18/1492 ,  A61B2017/22042 ,  A61B2018/00083 ,  A61B2018/00214 ,  A61B2018/144 ,  A61M25/0068 ,  A61M25/0082 ,  A61M25/0127 ,  A61M25/09 ,  A61M2025/0166 ,  A61M2025/09175 ,  A61M2025/09183 ,  A61M2205/054 ,  A61M2205/103 ,  A61M2205/3515

    摘要： This invention describes an occlusion crossing apparatus for creating an opening in occluded tissue at a target location in interventional and surgical applications with simultaneous or nearly simultaneous intravascular imaging. In particular, the present invention is concerned with a magnetically guidable occlusion crossing apparatus and methods of using same together with intravascular ultrasound imaging, said occlusion crossing apparatus being usable in combination with a magnetic field and comprising an ultrasound imaging catheter with at least one ultrasound transducer at its distal tip; the catheter including a lumen through which a magnetically steered guidewire is passed and extends beyond the distal end of the catheter; the guidewire possibly comprising an electrode at its distal end for delivery of ablative electrical energy at a target location in a body lumen; and at least one magnetic guiding element mounted to the guidewire for orienting the portion of the guidewire that extends from the distal tip of the imaging catheter and placing the tip of the guidewire at the desired target location.

    摘要翻译： 本发明描述了一种闭塞交叉装置，用于在具有同时或几乎同时的血管内成像的介入和外科应用中在目标位置处的闭塞组织中形成开口。 特别地，本发明涉及磁导引阻塞交叉装置及其与血管内超声成像一起使用的方法，所述闭塞交叉装置可与磁场组合使用，并且包括具有至少一个超声换能器的超声成像导管 在其远端; 所述导管包括内腔，磁导杆引导线穿过所述内腔延伸超过所述导管的远端; 所述导丝可能包括在其远端处的电极，用于在体腔内的目标位置处输送消融电能; 以及安装到所述导丝的至少一个磁性引导元件，用于使所述导丝的从所述成像导管的远侧末端延伸的部分定向，并将所述导丝的末端放置在期望的目标位置。

    GUIDEWIRES WITH IMPROVED FATIGUE LIFE AND METHODS OF MAKING THE SAME
    10.
    发明申请
    GUIDEWIRES WITH IMPROVED FATIGUE LIFE AND METHODS OF MAKING THE SAME 有权
    具有改进的疲劳寿命的指南及其制造方法

    公开(公告)号：US20090118705A1

    公开(公告)日：2009-05-07

    申请号：US11934659

    申请日：2007-11-02

    申请人： Hancun Chen ,  Peter Skujins

    发明人： Hancun Chen ,  Peter Skujins

    IPC分类号： A61M25/09 ,  B23P11/00

    CPC分类号： A61M25/09 ,  A61M2025/09066 ,  A61M2025/09108 ,  A61M2025/09133

    摘要： A medical device, such as a medical guidewire, having a portion including an inner zone of material and an outer peripheral zone of material surrounding the inner zone of material. The inner zone of material has a first coefficient of thermal expansion and the outer peripheral zone of material has a second coefficient of thermal expansion less than the first coefficient of thermal expansion, wherein at an operating temperature the outer peripheral zone of material opposes expansion of the inner zone of material such that the outer peripheral zone of material exerts a compressive stress on the inner zone of material.

    摘要翻译： 具有包括材料的内部区域和围绕材料的内部区域的材料的外围区域的部分的医疗装置，例如医疗导丝。 材料的内部区域具有第一热膨胀系数，并且材料的外周区域具有小于第一热膨胀系数的第二热膨胀系数，其中在工作温度下，材料的外周区域反对膨胀 材料的内部区域，使得材料的外周区域在材料的内部区域上施加压缩应力。