公开(公告)号：US20140329292A1

公开(公告)日：2014-11-06

申请号：US14020054

申请日：2013-09-06

Applicant: DYADIC INTERNATIONAL, INC.

Inventor： Mark A. EMARLFARB ,  Alexander Vasilievich Gusakov ,  Peter J. Punt ,  Jan Cornelis Verdoes ,  Arkady Panteleimonovich Sinitsyn ,  Elena Vlasenko ,  Sandra Wihelmina Agnes Hinz ,  Mark Gosink ,  Zhijie Jiang

IPC: C12N9/24 ,  C12N9/42 ,  C12N9/26

CPC classification number: C12N9/248 ,  C07H21/00 ,  C12N9/2402 ,  C12N9/2408 ,  C12N9/2434 ,  C12N9/2471 ,  C12Y301/01072 ,  C12Y302/01023 ,  C12Y302/01037 ,  C12Y302/01055 ,  C12Y302/01139 ,  C12Y302/01151 ,  C12Y302/01155 ,  Y02E50/16 ,  Y02E50/17

Abstract: This invention relates to novel enzymes and novel methods for producing the same. More specifically this invention relates to a variety of fungal enzymes. Nucleic acid molecules encoding such enzymes, compositions, recombinant and genetically modified host cells, and methods of use are described. The invention also relates to a method to convert lignocellulosic biomass to fermentable sugars with enzymes that degrade the lignocellulosic material and novel combinations of enzymes, including those that provide a synergistic release of sugars from plant biomass. The invention also relates to a method to release cellular content by degradation of cell walls. The invention also relates to methods to use the novel enzymes and compositions of such enzymes in a variety of other processes, including washing of clothing, detergent processes, biorefining, deinking and biobleaching of paper and pulp, and treatment of waste streams.

Abstract translation: 本发明涉及新型酶及其生产方法。 更具体地，本发明涉及各种真菌酶。 描述了编码这种酶，组合物，重组和遗传修饰的宿主细胞的核酸分子和使用方法。 本发明还涉及将木质纤维素生物质转化为可发酵糖的方法，该酶用于降解木质纤维素材料和酶的新组合，包括提供来自植物生物质的糖的协同释放的酶。 本发明还涉及通过细胞壁降解释放细胞内容物的方法。 本发明还涉及在各种其它方法中使用新型酶和这些酶的组合物的方法，包括洗涤衣物，洗涤剂方法，生物精制，纸和纸浆的脱墨和生物漂白以及废物流的处理。