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51 条记录 (耗时 0.022 秒)

    Devices and methods for isolating RNA
    1.
    发明申请
    Devices and methods for isolating RNA 审中-公开
    用于分离RNA的装置和方法

    公开(公告)号：US20050026153A1

    公开(公告)日：2005-02-03

    申请号：US10631189

    申请日：2003-07-31

    申请人： Claudia Iannotti ,  John Link ,  Barry Boyes

    发明人： Claudia Iannotti ,  John Link ,  Barry Boyes

    IPC分类号： C12N15/09 ,  B01D39/20 ,  C12N15/10 ,  C12Q1/68 ,  C12N1/08

    CPC分类号： C12N15/1006

    摘要： Devices and methods for isolating nucleic acid is disclosed herein. In particular, the isolation of total cellular RNA is discussed. Additionally, devices and methods for reducing genomic DNA in a biological sample without introducing harmful contaminants, and without significantly increasing the time required for the overall procedure being performed on a sample are presented.

    摘要翻译： 本文公开了用于分离核酸的装置和方法。 特别地，讨论了总细胞RNA的分离。 另外，提供了用于在不引入有害污染物的情况下还原生物样品中的基因组DNA并且不显着增加对样品进行总体程序所需的时间的装置和方法。

    Methods of using a DNase I-like enzyme
    5.
    发明申请
    Methods of using a DNase I-like enzyme 审中-公开
    使用DNA酶I样酶的方法

    公开(公告)号：US20060223073A1

    公开(公告)日：2006-10-05

    申请号：US11097868

    申请日：2005-03-31

    申请人： Barry Boyes ,  Rhonda Taylor ,  John Link

    发明人： Barry Boyes ,  Rhonda Taylor ,  John Link

    IPC分类号： C12Q1/68 ,  C12P19/34 ,  C12N9/22

    CPC分类号： C12P19/34 ,  C12N9/22

    摘要： Methods for expanding conditions of use of a DNase I-like enzyme are disclosed as are compositions and kits comprising a DNAse I-like enzyme. Compositions comprising storage-stable forms of a DNase I-like enzyme and methods for producing such compositions are also disclosed.

    摘要翻译： 公开了用于扩增DNA酶I样酶的使用条件的方法，是包含DNA酶I样酶的组合物和试剂盒。 还公开了包含DNA酶I样酶的储存稳定形式的组合物和用于制备这些组合物的方法。

    Silinane compounds as cysteine protease inhibitors
    6.
    发明申请
    Silinane compounds as cysteine protease inhibitors 审中-公开
    硅烷化合物作为半胱氨酸蛋白酶抑制剂

    公开(公告)号：US20070088001A1

    公开(公告)日：2007-04-19

    申请号：US10587867

    申请日：2005-01-31

    申请人： John Link ,  Michael Graupe

    发明人： John Link ,  Michael Graupe

    IPC分类号： A61K31/695 ,  C07F7/08

    CPC分类号： C07F7/0812 ,  C07F7/081

    摘要： The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is also directed to pharmaceutical compositions comprising these compounds and processes for preparing them. The present invention is also directed to the use of these inhibitors in combination with a therapy that causes a deleterious immune response in patients receiving the therapy.

    摘要翻译： 本发明涉及半胱氨酸蛋白酶，特别是组织蛋白酶B，K，L，F和S的抑制剂的化合物，因此可用于治疗由这些蛋白酶介导的疾病。 本发明还涉及包含这些化合物的药物组合物及其制备方法。 本发明还涉及这些抑制剂与在接受治疗的患者中引起有害免疫应答的疗法的组合的用途。

    Method for the preparation of higher antimony tricarboxylates
    10.
    发明授权
    Method for the preparation of higher antimony tricarboxylates 失效
    制备较高锑三羧酸盐的方法

    公开(公告)号：US4488997A

    公开(公告)日：1984-12-18

    申请号：US412409

    申请日：1982-08-27

    申请人： Richard F. Miller ,  John Link

    发明人： Richard F. Miller ,  John Link

    IPC分类号： C07C51/41 ,  C11C1/00

    CPC分类号： C07C51/412

    摘要： Antimony tricarboxylates of higher carboxylic acids can be prepared by(a) reacting antimony oxide with an anhydride of a lower organic acid,(b) reacting the product from (a) with at least one higher carboxylic acid at a temperature sufficient to vaporize volatile material and removing said volatile material, and(c) recovering the antimony tricarboxylate of said higher carboxylic acid.

    摘要翻译： 高级羧酸的三羧酸锑可以通过（a）使氧化锑与较低有机酸的酸酐反应来制备，（b）使得产物（a）与至少一种较高级羧酸在足以蒸发挥发性物质的温度下反应 并除去所述挥发性物质，和（c）回收所述较高级羧酸的三羧酸锑。