摘要:
Antiandrogenic compositions comprising an effective amount of at least one compound of the formula ##STR1## wherein X and Y are individually selected from the group consisting of hydrogen, halogen, --CF.sub.3, --NO.sub.3 and alkylthio of 1 to 4 carbon atoms and R is selected from the group consisting of hydrogen, alkyl of 1 to 6 carbon atoms, phenyl, benzyl and hydroxymethyl and an inert pharmaceutical carrier and a method of inducing antiandrogenic activity in warm-blooded animals as well as novel oxadiazines of formula I with the proviso that when R is other than benzyl or hydroxymethyl at least one of X and Y is alkylthio of 1 to 4 carbon atoms.
摘要:
Novel ureas of the formula ##STR1## wherein A and B are chlorine or A is chlorine or hydrogen and B is --CF.sub.3, R and R.sub.1 are individually alkyl of 1 to 3 carbon atoms and R.sub.2 is alkyl of 1 to 6 carbon atoms optionally substituted with a halogen having herbicidal properties, particularly useful in cultivated grass crops and their preparation and use.
摘要:
Novel thiadiazoles of the formula ##STR1## wherein R is selected from the group consisting of alkoxy of 1 to 8 carbon atoms, cycloalkyloxy of 3 to 7 carbon atoms, alkylthio of 1 to 8 carbon atoms optionally substituted with carbalkoxy of 2 to 5 carbon atoms, alkenylthio of 2 to 4 carbon atoms, ##STR2## and benzyloxy, benzylthio, benzyl and phenyl, all aryl being optionally substituted with 1 to 2 members of the group consisting of chlorine, bromine, alkyl of 1 to 3 carbon atoms and alkoxy of 1 to 3 carbon atoms, Z and Z.sub.1 are alkyl of 1 to 4 carbon atoms and R.sub.1 is selected from the group consisting of alkyl of 1 to 6 carbon atoms optionally substituted with a member of the group consisting of chlorine, bromine and alkyloxy of 1 to 4 carbon atoms, phenyl optionally substituted with 1 to 2 members of the group consisting of bromine, chlorine, alkyl of 1 to 3 carbon atoms and alkoxy of 1 to 3 carbon atoms, alkenyl of 2 to 4 carbon atoms optionally substituted with at least one member of the group consisting of chlorine and alkoxy of 1 to 3 carbon atoms, ##STR3## and carbalkoxy of 2 to 6 carbon atoms and X is selected from the group consisting of alkyl of 1 to 4 carbon atoms and alkenyl of 2 to 4 carbon atoms, both optionally substituted with at least one chlorine having herbicidal properties and novel intermediates.
摘要:
Imidazolidines of the formula ##STR1## wherein X is selected from the group consisting of oxygen and amine which inhibit the effects of androgens on peripheric receptors without interfering with normal hypophysial functions.
摘要:
Antiandrogenic compositions wherein the active principle is 3-(3',4'-dichlorophenyl)-5,5-dimethyl-oxazolidine-2,4-dione of the formula ##STR1## are useful for inducing antiandrogenic activity in warm-blooded animals.
摘要:
Novel crotonanilides of the formula ##STR1## wherein R is selected from the group consisting of ##STR2## X is selected from the group consisting of alkyl of 1 to 8 carbon atoms and cycloalkyl of 3 to 7 carbon atoms, Z is alkyl of 1 to 6 carbon atoms, X.sub.1 is alkoxyalkyl of 2 to 12 carbon atoms, X.sub.2 is alkyl of 1 to 3 carbon atoms, X.sub.3 is selected from the group consisting of alkyl or alkoxy of 1 to 3 carbon atoms and R.sub.1 and R.sub.2 are individually alkyl of 1 to 3 carbon atoms having pre- and post-emergence herbicidal activity.
摘要:
Novel crotonamides of the formula ##STR1## wherein R is selected from the group consisting of adamantyl, bornyl, 5',6'-dihydroendo-5'-dicyclopentadienyl and saturated and unsaturated cycloalkyl of 3 to 8 carbon atoms optionally substituted with a member of the group consisting of alkyl of 1 to 6 carbon atoms, hydroxy, chlorine and alkoxycarbonyl of 1 to 6 alkyl carbon atoms and R.sub.1 is alkyl of 1 to 3 carbon atoms having pre- and post-emergence herbicidal properties.
摘要:
Novel crotonanilides of the formula ##STR1## wherein R' is selected from the group consisting of ##STR2## R and R.sub.1 are alkyl of 1 to 6 carbon atoms and R.sub.2 is selected from the group consisting of hydrogen, methyl and methoxy having pre- and post-emergence herbicidal activity.
摘要:
Thiazole derivatives of the formula ##SPC1##Wherein A is alkylene of 3 to 5 carbon atoms optionally substituted with a member of the group consisting of =0 and ##EQU1## wherein R' is alkyl of 1 to 5 carbon atoms and R is alkyl of 2 to 3 carbon atoms having insecticidal and/or acaricidal properties and their preparation.
摘要:
Novel thiazole derivatives of the formula ##EQU1## wherein A is alkylene of 3 to 5 carbon atoms optionally substituted with a member of the group consisting of =0 and ##EQU2## wherein R' is alkyl of 1 to 5 carbon atoms and R is alkyl of 2 to 3 carbon atoms having insecticidal and/or acaricidal properties and their preparation.