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    Secure, swift cryptographic key exchange
    1.
    发明授权
    Secure, swift cryptographic key exchange 失效
    安全，快速的加密密钥交换

    公开(公告)号：US5835592A

    公开(公告)日：1998-11-10

    申请号：US534960

    申请日：1995-09-28

    申请人： Chung Nan Chang ,  Chuan Kuan Yuan ,  Feng Qi Hao

    发明人： Chung Nan Chang ,  Chuan Kuan Yuan ,  Feng Qi Hao

    IPC分类号： H04L9/08 ,  H04L9/00 ,  H04K1/00

    CPC分类号： H04L9/0841 ,  H04L9/3093

    摘要： Using the present cryptographic key exchange protocol, a first of two cryptographic units selects quantities "A" and "B." That same unit then applies a mathematical function ".PHI..sub.1 " to A and B to compute a third quantity "C.". A and B and the function .PHI..sub.1 posses the property that knowing A or B, and C, and the function .PHI..sub.1, it is mathematically impossible to compute the unknown quantity B or A. The first unit then transmits A together C to the second unit while retaining B. The second unit selects a fourth quantity "D" and then applies a second mathematical function .PHI..sub.2 to A and D to compute a quantity "E" which the second unit transmits to the first unit while retaining D. The quantities A and D and the function .PHI..sub.2 must posses the property that knowing D and E, and the function .PHI..sub.2, it is mathematically impossible to compute the unknown quantity D. Then the second unit applies a third mathematical function ".PSI..sub.2 " to D and C to compute the key "K." The first unit upon receiving the quantity E then applies a fourth mathematical function .PSI..sub.1 to B and E to also compute the key K.

    摘要翻译： 使用本密码密钥交换协议，两个加密单元中的第一个选择数量“A”和“B.” 那个同一单元然后将数学函数“PHI 1”应用于A和B来计算第三数量“C.”。 A和B和函数PHI 1具有知道A或B和C的属性，以及函数PHI 1，在数学上不可能计算未知数量B或A.第一单元然后将A一起发送到第二个 同时保持B.第二单元选择第四数量“D”，然后将第二数学函数PHI 2应用于A和D以计算第二单元在保留D的同时向第一单元发送的数量“E”。数量 A和D和函数PHI 2必须具有知道D和E的属性，以及函数PHI 2，在数学上不可能计算未知数量D.然后第二单元将第三数学函数“PSI 2”应用于D 和C来计算密钥“K.” 接收数量E的第一单元然后将第四数学函数PSI 1应用于B和E也计算密钥K.

    Methods of reducing T cell-mediated immune responses with multimeric P-selectin and/or E-selectin compounds
    4.
    发明授权
    Methods of reducing T cell-mediated immune responses with multimeric P-selectin and/or E-selectin compounds 有权
    用多聚体P-选择蛋白和/或E-选择素化合物降低T细胞介导的免疫应答的方法

    公开(公告)号：US08628775B2

    公开(公告)日：2014-01-14

    申请号：US12562515

    申请日：2009-09-18

    申请人： Rong-Hwa Lin ,  Chung Nan Chang

    发明人： Rong-Hwa Lin ,  Chung Nan Chang

    IPC分类号： A61K38/17 ,  C07K14/435

    CPC分类号： C07K16/28 ,  A61K2039/505 ,  C07K14/70564 ,  C07K16/2896 ,  C07K2317/73 ,  C07K2319/30 ,  G01N2500/10 ,  G01N2800/52

    摘要： Multimeric compounds that bind to P-Selectin Glycoprotein 1 (PSGL-1) on the surface of T cells or natural killer (NK) cells can be used to induce T cell or NK cell depletion and/or to induce T cell or NK cell apoptosis. The multimeric compounds and methods of the invention can be used to control unwanted T cell- or NK cell-mediated immune responses in conditions such as inflammatory diseases, autoimmune diseases, transplant rejection, and allergic diseases.

    摘要翻译： 可以将T细胞或天然杀伤（NK）细胞表面上结合P-选择蛋白糖蛋白1（PSGL-1）的多聚体化合物诱导T细胞或NK细胞消耗和/或诱导T细胞或NK细胞凋亡 。 本发明的多聚体化合物和方法可用于在诸如炎性疾病，自身免疫疾病，移植排斥反应和过敏性疾病的病症中控制不需要的T细胞或NK细胞介导的免疫应答。