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19 条记录 (耗时 0.053 秒)

    Treating asthma
    3.
    发明授权
    Treating asthma 失效
    治疗哮喘

    公开(公告)号：US4073915A

    公开(公告)日：1978-02-14

    申请号：US773906

    申请日：1977-03-03

    申请人： Ulrich Martin

    发明人： Ulrich Martin

    IPC分类号： A61K31/445

    CPC分类号： A61K31/445 ,  Y10S514/826

    摘要： The present invention relates to the use of the known compound 4-(1-methyl-4-piperidylidene)-4H-benzo 4,5!cyclohepta 1,2-b!thiophen-10(9H)-one for the prevention and treatment of allergic conditions such as allergic asthma.

    摘要翻译： 本发明涉及已知的化合物4-（1-甲基-4-哌啶基）-4H-苯并[4,5]环庚并[1,2-b]噻吩-10（9H） - 酮，用于 预防和治疗过敏性哮喘等过敏性疾病。

    Method for the production of differentiated respiratory epithelial cells
    7.
    发明授权
    Method for the production of differentiated respiratory epithelial cells 有权

    公开(公告)号：US09765303B2

    公开(公告)日：2017-09-19

    申请号：US13983299

    申请日：2012-02-03

    申请人： Ulrich Martin ,  Christina Mauritz

    发明人： Ulrich Martin ,  Christina Mauritz

    IPC分类号： C12N5/071 ,  C12Q1/68 ,  G01N33/50

    CPC分类号： C12N5/0688 ,  C12N2501/01 ,  C12N2501/117 ,  C12N2501/39 ,  C12Q1/6881 ,  C12Q1/6897 ,  G01N33/5044

    摘要： The present invention relates to a method for the production of differentiated respiratory epithelial cells comprising: (a) providing a cell population comprising or consisting of precursor cells of respiratory epithelial cells; (b) culturing the cell population of (a) in culture medium to which keratinocyte growth factor has been added; wherein the cultured cell population is supplemented with a glucocorticoid, a cAMP analog and a cAMP elevating agent and wherein said supplementation is either simultaneously with the addition of keratinocyte growth factor in step (b) or prior or subsequently to the addition of keratinocyte growth factor in step (b), thereby differentiating said precursor cells into respiratory epithelial cells. The present invention further relates to the cell(s) obtained by the method of the invention for use in treating or preventing a respiratory disease and to a method for identifying a compound having an pharmacological, cytotoxic, proliferative, transforming or differentiating effect on the differentiated respiratory epithelial cells obtained by the method of the invention.

    Optical particle detector and detection method
    8.
    发明授权
    Optical particle detector and detection method 有权
    光学粒子探测器及检测方法

    公开(公告)号：US09557259B2

    公开(公告)日：2017-01-31

    申请号：US13056374

    申请日：2009-07-22

    申请人： Alois Friedberger ,  Ulrich Martin ,  Leonhard Meixner

    发明人： Alois Friedberger ,  Ulrich Martin ,  Leonhard Meixner

    IPC分类号： G01N15/14 ,  B01D67/00 ,  B01D71/02 ,  G01N35/00 ,  G01N1/22

    CPC分类号： G01N15/1475 ,  B01D67/0062 ,  B01D71/021 ,  G01N35/0098 ,  G01N2001/2217

    摘要： A particle detector apparatus for optically ascertaining a number of particles arranged on a surface of, for example, a particle filter. The particle detector apparatus includes a light source, an optical focusing device, a spatially resolving light detector and an evaluation device. The light source emits source light onto the surface. The optical focusing device focuses image light that is emitted from the surface in response to the source light onto the spatially resolving light detector. The spatially resolving light detector includes light sensors that measure brightness values based on the image light, such that the light detector produces image data based on the brightness values delivered by the light sensors. The evaluation device then ascertains the number of particles based on the image data.

    摘要翻译： 一种用于光学地确定布置在例如颗粒过滤器的表面上的颗粒的数量的颗粒检测器装置。 粒子检测装置包括光源，光聚焦装置，空间分辨光检测器和评估装置。 光源将光源发射到表面上。 光聚焦装置将响应于源光的从表面发射的图像光聚焦到空间分辨光检测器上。 空间分辨光检测器包括基于图像光测量亮度值的光传感器，使得光检测器基于由光传感器传递的亮度值产生图像数据。 然后，评估装置基于图像数据确定粒子的数量。

    OPTICAL PARTICLE DETECTOR AND DETECTION METHOD
    9.
    发明申请
    OPTICAL PARTICLE DETECTOR AND DETECTION METHOD 有权
    光学粒子检测器和检测方法

    公开(公告)号：US20110311996A1

    公开(公告)日：2011-12-22

    申请号：US13056374

    申请日：2009-07-22

    申请人： Alois Friedberger ,  Ulrich Martin ,  Leonhard Meixner

    发明人： Alois Friedberger ,  Ulrich Martin ,  Leonhard Meixner

    IPC分类号： C12Q1/02 ,  G01N33/569 ,  C12M1/34

    CPC分类号： G01N15/1475 ,  B01D67/0062 ,  B01D71/021 ,  G01N35/0098 ,  G01N2001/2217

    摘要： A particle detector apparatus for optically ascertaining a number of particles arranged on a surface, for example, a particle filter. The particle detector apparatus includes a light source, an optical focusing device, a spatially resolving light detector and an evaluation device. The light source emits source light onto the surface. The optical focusing device focuses image light that is emitted from the surface in response to the source light onto the spatically resolving light detector. The spatially resolving light detector includes light sensors that measure brightness values based on the image light, such that the light detector produces image data based on the brightness values delivered by the light sensors. The evaluation device then ascertains the number of particles based on the image data.

    摘要翻译： 一种用于光学地确定布置在表面上的颗粒数量的颗粒检测器装置，例如颗粒过滤器。 粒子检测装置包括光源，光聚焦装置，空间分辨光检测器和评估装置。 光源将光源发射到表面上。 光聚焦装置将响应于源光的从表面发射的图像光聚焦到分光光检测器上。 空间分辨光检测器包括基于图像光测量亮度值的光传感器，使得光检测器基于由光传感器传递的亮度值产生图像数据。 然后，评估装置基于图像数据确定粒子的数量。