公开(公告)号：US20240198332A1

公开(公告)日：2024-06-20

申请号：US18593787

申请日：2024-03-01

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: B01L3/00 ,  C12Q1/6869 ,  C12Q1/6874 ,  G01N33/543 ,  G01N33/68

CPC classification number: B01L3/502715 ,  B01L3/502707 ,  B01L3/502761 ,  C12Q1/6869 ,  C12Q1/6874 ,  G01N33/54386 ,  G01N33/6842 ,  B01L2200/0647 ,  B01L2200/12 ,  B01L2300/0663 ,  B01L2300/0883 ,  B01L2300/12 ,  B01L2300/163 ,  B01L2300/18 ,  C12Q2600/158 ,  G01N2570/00

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

公开(公告)号：US20230348974A1

公开(公告)日：2023-11-02

申请号：US18219545

申请日：2023-07-07

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: C12Q1/6874 ,  G01N33/68 ,  G01N33/543 ,  B01L3/00

CPC classification number: C12Q1/6874 ,  G01N33/6842 ,  G01N33/54386 ,  B01L3/502761 ,  C12Q2600/158 ,  B01L2200/0647 ,  B01L2300/0883 ,  G01N2570/00

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

公开(公告)号：US20240367167A1

公开(公告)日：2024-11-07

申请号：US18776193

申请日：2024-07-17

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: B01L3/00 ,  C12Q1/6869 ,  C12Q1/6874 ,  G01N33/543 ,  G01N33/68

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

公开(公告)号：US20230001413A1

公开(公告)日：2023-01-05

申请号：US17896742

申请日：2022-08-26

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: B01L3/00 ,  C12Q1/6869

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

公开(公告)号：US20250050301A1

公开(公告)日：2025-02-13

申请号：US18908638

申请日：2024-10-07

Applicant: Cellanome, Inc.

Inventor： Stephen C. MACEVICZ ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR ,  Tarun Kumar KHURANA

IPC: B01J19/00 ,  C12N15/10

Abstract: The invention is directed to methods and systems for producing a surface coated with a plurality of spatial barcodes. In one aspect, beads carrying barcode oligonucleotides are disposed on a surface after which hydrogel chambers are synthesized around each bead and barcode oligonucleotides are released to be captured on the surface in the interiors of the chambers. Captured oligonucleotide barcodes are amplified and optionally sequenced to form a coating of spatial barcodes.

公开(公告)号：US20220226820A1

公开(公告)日：2022-07-21

申请号：US17715843

申请日：2022-04-07

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: B01L3/00 ,  C12Q1/6869

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

公开(公告)号：US20240301465A1

公开(公告)日：2024-09-12

申请号：US18534328

申请日：2023-12-08

Applicant: Cellanome, Inc.

Inventor： Pier Federico GHERARDINI ,  Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: C12Q1/6806 ,  C12N15/10 ,  C12Q1/6874

CPC classification number: C12Q1/6806 ,  C12N15/1096 ,  C12Q1/6874

Abstract: The invention is directed to methods and systems for analyzing transcriptomes of single cells. In some embodiments, the invention comprises methods for analyzing transcriptomes of a plurality of single cells on separate regions of the same planar surface.

公开(公告)号：US20220219170A1

公开(公告)日：2022-07-14

申请号：US17669315

申请日：2022-02-10

Applicant: Cellanome, Inc.

Inventor： Tarun Kumar KHURANA ,  Ali AGAH ,  Yir-Shyuan WU ,  Filiz Gorpe YASAR

IPC: B01L3/00 ,  C12Q1/6869

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.