公开(公告)号：US20190351673A1

公开(公告)日：2019-11-21

申请号：US16414752

申请日：2019-05-16

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Mike Hazel ,  Richard Day ,  Richard Hammond ,  James Brown ,  Rodney Richardson ,  Thomas Redman ,  Devin Leake

IPC: B41J2/045 ,  C12P19/34 ,  G06N3/12 ,  B41J2/165 ,  B41J2/05

Abstract: Provided herein are systems and methods for storing digital information by assembling an identifier nucleic acid molecule from at least a first component nucleic acid molecule and a second component nucleic acid molecule. The system may include a first printhead configured to dispense a first droplet of a first solution comprising the first component nucleic acid molecule onto a coordinate on a substrate, and a second printhead configured to dispense a second droplet of a second solution comprising the second component nucleic acid molecule onto the coordinate on the substrate, such that the first and second component nucleic acid molecules are collocated on the substrate. The system may include a finisher that dispenses a reaction mix onto the coordinate on the substrate to physically link the first and second component nucleic acid molecules, provides a condition necessary to physically link the first and second component nucleic acid molecules, or both.

公开(公告)号：US12005704B2

公开(公告)日：2024-06-11

申请号：US16414752

申请日：2019-05-16

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Mike Hazell ,  Richard Day ,  Richard Hammond ,  James Brown ,  Rodney Richardson ,  Thomas Redman ,  Devin Leake

IPC: B41J2/045 ,  B41J2/05 ,  B41J2/165 ,  C12P19/34 ,  G06N3/123

CPC classification number: B41J2/04505 ,  B41J2/04526 ,  B41J2/05 ,  B41J2/1652 ,  C12P19/34 ,  G06N3/123

Abstract: Provided herein are systems and methods for storing digital information by assembling an identifier nucleic acid molecule from at least a first component nucleic acid molecule and a second component nucleic acid molecule. The system may include a first printhead configured to dispense a first droplet of a first solution comprising the first component nucleic acid molecule onto a coordinate on a substrate, and a second printhead configured to dispense a second droplet of a second solution comprising the second component nucleic acid molecule onto the coordinate on the substrate, such that the first and second component nucleic acid molecules are collocated on the substrate. The system may include a finisher that dispenses a reaction mix onto the coordinate on the substrate to physically link the first and second component nucleic acid molecules, provides a condition necessary to physically link the first and second component nucleic acid molecules, or both.

公开(公告)号：US20240013063A1

公开(公告)日：2024-01-11

申请号：US18230273

申请日：2023-08-04

Applicant: CATALOG TECHNOLOGIES, INC.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Darren R. Link

IPC: G06N3/123 ,  G06F16/245 ,  G06F16/22 ,  G16B30/00 ,  G16B50/00 ,  G16B30/20 ,  C12N9/22

CPC classification number: G06N3/123 ,  G06F16/245 ,  G06F16/2272 ,  G16B30/00 ,  G16B50/00 ,  G16B30/20 ,  C12N9/22

Abstract: Methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool. But, more generally, specifying unique bytes in a bytestream by unique subsets of nucleic acid sequences. Also disclosed are methods for generating unique nucleic acid sequences without base-by-base synthesis using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).

公开(公告)号：US20230376788A1

公开(公告)日：2023-11-23

申请号：US18230385

申请日：2023-08-04

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia

IPC: G06N3/123 ,  G06F5/08 ,  C12N9/22

CPC classification number: G06N3/123 ,  G06F5/08 ,  C12N9/22 ,  C12N2310/20 ,  G16B20/00

Abstract: Methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool. But, more generally, specifying unique bytes in a bytestream by unique subsets of nucleic acid sequences. Also disclosed are methods for generating unique nucleic acid sequences without base-by-base synthesis using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).

公开(公告)号：US11535842B2

公开(公告)日：2022-12-27

申请号：US17069420

申请日：2020-10-13

Applicant: CATALOG TECHNOLOGIES, INC.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Devin Leake

IPC: C12N15/10 ,  G06N3/00 ,  G06N3/12 ,  H04L9/08 ,  H04L9/32

Abstract: Methods and systems for security, authentication, tagging, and tracking using nucleic acid (e.g., deoxyribonucleic acid) molecules encoding information. Unique nucleic acid molecules are efficiently produced from pre-fabricated fragments to quickly produce libraries of nucleic acid molecules encoding encrypted or randomized information. Physical objects or artifacts can be tagged with libraries to authenticate the objects, grant access to secured assets or locations, or track the objects or entities. Chemical methods can be applied to verify authenticity, decrypt, or decode information stored in the libraries.

公开(公告)号：US20250028974A1

公开(公告)日：2025-01-23

申请号：US18647003

申请日：2024-04-26

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Darren R. Link

IPC: G06N3/123 ,  C12N9/22 ,  C12N15/10 ,  C40B50/06 ,  G06F16/22 ,  G06F16/245 ,  G11C13/00 ,  G16B30/00 ,  G16B30/20 ,  G16B50/00 ,  G16B99/00

Abstract: Methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool. But, more generally, specifying unique bytes in a bytestream by unique subsets of nucleic acid sequences. Also disclosed are methods for generating unique nucleic acid sequences without base-by-base synthesis using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).

公开(公告)号：US20230376787A1

公开(公告)日：2023-11-23

申请号：US18230383

申请日：2023-08-04

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia

IPC: G06N3/123 ,  G06F5/08 ,  C12N9/22

CPC classification number: G06N3/123 ,  G06F5/08 ,  C12N9/22 ,  C12N2310/20 ,  G16B20/00

Abstract: Methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool. But, more generally, specifying unique bytes in a bytestream by unique subsets of nucleic acid sequences. Also disclosed are methods for generating unique nucleic acid sequences without base-by-base synthesis using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).

公开(公告)号：US20230376786A1

公开(公告)日：2023-11-23

申请号：US18230382

申请日：2023-08-04

Applicant: Catalog Technologies, Inc.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia

IPC: G06N3/123 ,  G06F5/08 ,  C12N9/22

CPC classification number: G06N3/123 ,  G06F5/08 ,  C12N9/22 ,  C12N2310/20 ,  G16B20/00

Abstract: Methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool But, more generally, specifying unique bytes in a bytestream by unique subsets of nucleic acid sequences. Also disclosed are methods for generating unique nucleic acid sequences without base-by-base synthesis using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).

公开(公告)号：US20230295607A1

公开(公告)日：2023-09-21

申请号：US17989925

申请日：2022-11-18

Applicant: CATALOG TECHNOLOGIES, INC.

Inventor： Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia ,  Devin Leake

IPC: C12N15/10 ,  G06N3/00 ,  G06N3/123 ,  H04L9/08 ,  H04L9/32

CPC classification number: C12N15/1065 ,  G06N3/002 ,  G06N3/123 ,  H04L9/0869 ,  H04L9/3213

Abstract: Methods and systems for security, authentication, tagging, and tracking using nucleic acid (e.g., deoxyribonucleic acid) molecules encoding information. Unique nucleic acid molecules are efficiently produced from pre-fabricated fragments to quickly produce libraries of nucleic acid molecules encoding encrypted or randomized information. Physical objects or artifacts can be tagged with libraries to authenticate the objects, grant access to secured assets or locations, or track the objects or entities. Chemical methods can be applied to verify authenticity, decrypt, or decode information stored in the libraries.

公开(公告)号：US20230026655A1

公开(公告)日：2023-01-26

申请号：US17674170

申请日：2022-02-17

Applicant: CATALOG TECHNOLOGIES, INC.

Inventor： Devin Leake ,  Milena Lazova ,  Sarah Flickinger ,  Nathaniel Roquet ,  Hyunjun Park ,  Swapnil P. Bhatia

IPC: C12N15/10 ,  G06N3/12 ,  G11C13/02

Abstract: The present disclosure discloses methods and systems for encoding digital information in nucleic acid (e.g., deoxyribonucleic acid) molecules without base-by-base synthesis, by encoding bit-value information in the presence or absence of unique nucleic acid sequences within a pool, comprising specifying each bit location in a bit-stream with a unique nucleic sequence and specifying the bit value at that location by the presence or absence of the corresponding unique nucleic acid sequence in the pool. Also disclosed are chemical methods for generating unique nucleic acid sequences using combinatorial genomic strategies (e.g., assembly of multiple nucleic acid sequences or enzymatic-based editing of nucleic acid sequences).