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公开(公告)号：US20240335219A1
公开(公告)日：2024-10-10
申请号：US18745396
申请日：2024-06-17
申请人： Bone Solutions, Inc.
发明人： Frankie Morris , Drew Diaz , Brandon Roller
IPC分类号： A61B17/86 , A61F2/30 , A61F2/44 , A61L27/04 , A61L27/06 , A61L27/12 , A61L27/18 , A61L27/54 , A61L27/56
CPC分类号： A61B17/866 , A61F2/30771 , A61F2/3094 , A61F2/447 , A61L27/047 , A61L27/06 , A61L27/12 , A61L27/18 , A61L27/54 , A61L27/56 , A61F2002/30827 , A61F2002/30985 , A61F2310/00023 , A61F2310/00041 , A61F2310/00359 , A61L2300/102 , A61L2300/112 , A61L2300/412 , A61L2430/02 , A61L2430/24 , A61L2430/38
摘要： The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
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公开(公告)号：US12053215B2
公开(公告)日：2024-08-06
申请号：US18147167
申请日：2022-12-28
申请人： Bone Solutions, Inc.
发明人： Frankie Morris , Drew Diaz , Brandon Roller
IPC分类号： A61B17/86 , A61F2/30 , A61F2/44 , A61L27/04 , A61L27/06 , A61L27/12 , A61L27/18 , A61L27/54 , A61L27/56
CPC分类号： A61B17/866 , A61F2/30771 , A61F2/3094 , A61F2/447 , A61L27/047 , A61L27/06 , A61L27/12 , A61L27/18 , A61L27/54 , A61L27/56 , A61F2002/30827 , A61F2002/30985 , A61F2310/00023 , A61F2310/00041 , A61F2310/00359 , A61L2300/102 , A61L2300/112 , A61L2300/412 , A61L2430/02 , A61L2430/24 , A61L2430/38
摘要： The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
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公开(公告)号：US20180326125A1
公开(公告)日：2018-11-15
申请号：US15978570
申请日：2018-05-14
申请人： Bone Solutions, Inc.
发明人： Drew Diaz , Frankie L. Morris , Brandon Roller
CPC分类号： A61L27/58 , A61L27/025 , A61L27/12 , A61L2430/02 , A61L2430/38
摘要： The present invention relates to a material and method for promoting motion preservation in a bone. One preferred method comprises (a) accessing an interior of the bone, (a) mixing magnesia, potassium biphosphate, and a calcium phosphate with an aqueous solution forming an activated slurry, (c) applying an effective amount of the activated slurry to the interior of the bone, (d) allowing the activated slurry to set forming a bonded bone structure, and (e) permitting bone growth into the bonded bone structure to thereby promote motion preservation of the bone.
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公开(公告)号：US20230210570A1
公开(公告)日：2023-07-06
申请号：US18147167
申请日：2022-12-28
申请人： Bone Solutions, Inc.
发明人： Frankie Morris , Drew Diaz , Brandon Roller
IPC分类号： A61B17/86 , A61L27/12 , A61L27/18 , A61L27/54 , A61F2/44 , A61F2/30 , A61L27/56 , A61L27/06 , A61L27/04
CPC分类号： A61B17/866 , A61L27/12 , A61L27/18 , A61L27/54 , A61F2/447 , A61F2/30771 , A61L27/56 , A61F2/3094 , A61L27/06 , A61L27/047 , A61L2430/24 , A61F2310/00041 , A61F2002/30827 , A61F2310/00023 , A61F2310/00359 , A61L2430/02 , A61F2002/30985 , A61L2300/412 , A61L2300/112 , A61L2300/102 , A61L2430/38
摘要： The present disclosure provides a bone-implantable device and methods of use. The bone-implantable device comprises a body having an exterior surface, wherein a portion of the exterior surface includes a cured osteostimulative material comprising MgO.
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公开(公告)号：US20230218801A1
公开(公告)日：2023-07-13
申请号：US18000215
申请日：2021-05-27
申请人： Bone Solutions, Inc.
发明人： Frankie L. Morris , Brandon Roller
CPC分类号： A61L27/12 , A61L27/58 , A61L27/54 , A61L27/227 , A61L27/56 , A61L2430/02 , A61L2300/406 , A61L2300/232 , A61L2300/412
摘要： The present disclosure relates to a bio-material composition comprising a dry potassium phosphate based mixture omprising: MgO, monobasic potassium phosphate, monobasic sodium phosphate, proteoglycans, calcium sodium phosphosilicate, and an antibiotic, wherein a weight percent ratio of monobasic potassium phosphate to MgO is between about 3:1 and 1:1, wherein the dry otassium phosphate based mixture is configured to be mixed with the aqueous solution to thereby form a reabsorbable bio-material slurry, wherein the proteoglycans are between about 1-10 weight percent of the dry composition, and wherein the proteoglycans act as active regulators of collagen fibrillogenesis to thereby structure tissue of a patient by organizing a bone extracellular matrix.
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公开(公告)号：US20180326124A1
公开(公告)日：2018-11-15
申请号：US15978559
申请日：2018-05-14
申请人： Bone Solutions, Inc.
发明人： Drew Diaz , Frankie L. Morris , Brandon Roller
CPC分类号： A61L27/58 , A61L27/047 , A61L27/12 , A61L27/18 , A61L27/20 , A61L27/54 , A61L2300/406 , A61L2430/02
摘要： The present invention relates to a bio-material composition comprising: a dry potassium phosphate based mixture comprising (a) MgO, monobasic potassium phosphate, monobasic sodium phosphate, a reabsorbing agent, and a tertiary calcium phosphate, wherein the weight percent ratio of monobasic potassium phosphate to metal oxide is between about 3:1 and 1:1; and (b) an aqueous solution, wherein the dry potassium phosphate based mixture is mixed with the aqueous solution forming a reabsorbable bio-material slurry, wherein the reabsorbing agent is between about 1-10 weight percent of the dry composition, and wherein the reabsorbing agent is selected from the group consisting of a sugar compound, hydroxypropyl methyl cellulose (HPMC), carboxymethylcellulose (CMC), a poloxamer, and combinations thereof.
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