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    DEVICE AND METHODS FOR RENAL NERVE MODULATION
    3.
    发明申请
    DEVICE AND METHODS FOR RENAL NERVE MODULATION 审中-公开
    用于神经调节的装置和方法

    公开(公告)号：US20130123670A1

    公开(公告)日：2013-05-16

    申请号：US13647999

    申请日：2012-10-09

    申请人： BOSTON SCIENTIFIC SCIMED, INC.

    发明人： SCOTT R. SMITH

    IPC分类号： A61N7/00

    CPC分类号： A61N7/022 ,  A61B18/1815 ,  A61B18/20 ,  A61B2018/00636 ,  A61N2007/0078 ,  A61N2007/0091 ,  A61N2007/0095 ,  A61N2007/027

    摘要： Systems for nerve modulation are disclosed. An example system may include a first elongate element having a distal end and a proximal end and having at least one nerve modulation element disposed adjacent the distal end. The nerve modulation element may be an ultrasound transducer. Activation of the nerve modulation element may ablate multiple regions of a target area.

    摘要翻译： 公开了神经调制系统。 示例性系统可以包括具有远端和近端的第一细长元件，并且具有邻近远端设置的至少一个神经调制元件。 神经调制元件可以是超声换能器。 神经调节元件的激活可以消融目标区域的多个区域。

    ABLATION CATHETER WITH CRYOTHERMAL BALLOON
    6.
    发明申请
    ABLATION CATHETER WITH CRYOTHERMAL BALLOON 审中-公开
    带热气球的吸管

    公开(公告)号：US20130123770A1

    公开(公告)日：2013-05-16

    申请号：US13677011

    申请日：2012-11-14

    申请人： Boston Scientific Scimed, Inc.

    发明人： SCOTT R. SMITH

    IPC分类号： A61B18/08

    CPC分类号： A61B18/082 ,  A61B17/2202 ,  A61B2018/00023 ,  A61B2018/00404 ,  A61N7/022 ,  A61N2007/003

    摘要： A catheter for thermal modulation of renal nerves via thermal ablation, the catheter including a catheter shaft including a distal end, a proximal end, and two lumens—a first lumen and a second lumen—extending therethrough. A thermal heating element is located proximate the distal end of the catheter shaft. In addition, a phase-change cooling mechanism is configured to extract heat away from the thermal heating element. The phase-change cooling mechanism involves vaporization of a liquid refrigerant circulated to the distal end of the catheter shaft through the first lumen into a gas and exhausting the gas to the proximal end of the catheter shaft through the second lumen.

    摘要翻译： 一种用于通过热消融来热调节肾神经的导管，所述导管包括导管轴，所述导管轴包括远端，近端和两个腔 - 第一腔和第二腔 - 延伸穿过其中。 热加热元件位于导管轴的远端附近。 此外，相变冷却机构构造成从热发热元件提取热量。 相变冷却机构包括通过第一内腔循环到导管轴的远端的液体制冷剂蒸发成气体，并通过第二管腔将气体排出到导管轴的近端。

    BIPOLAR OFF-WALL ELECTRODE DEVICE FOR RENAL NERVE ABLATION
    7.
    发明申请
    BIPOLAR OFF-WALL ELECTRODE DEVICE FOR RENAL NERVE ABLATION 审中-公开
    用于肾神经退避的双极非球形电极装置

    公开(公告)号：US20150150626A1

    公开(公告)日：2015-06-04

    申请号：US14620859

    申请日：2015-02-12

    申请人： BOSTON SCIENTIFIC SCIMED, INC.

    发明人： MARK L. JENSON ,  SCOTT R. SMITH

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B2018/00267 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/00875

    摘要： A first spacing structure is provided at a distal end of a first catheter. The first spacing structure is configured to position at least one arterial electrode at a predefined distance away from a wall of the renal artery. A second spacing structure is provided at the distal end of the first catheter or at a distal end of a second catheter. The second spacing structure is configured to position at least one aortal electrode at a predefined distance away from a wall of the aorta. The arterial and aortal electrodes are operable as a bipolar electrode arrangement. The first and second spacing structures respectively maintain the arterial and aortal electrodes at a predefined distance away from the renal artery and aortal walls while electrical energy sufficient to ablate perivascular nerve tissue adjacent the renal artery and aortal walls is delivered by the bipolar electrode arrangement.

    摘要翻译： 第一间隔结构设置在第一导管的远端。 第一间隔结构构造成将远离肾动脉壁的预定距离定位至少一个动脉电极。 第二间隔结构设置在第一导管的远端处或在第二导管的远端处。 第二间隔结构被配置为将至少一个主动脉电极定位成远离主动脉壁的预定距离。 动脉和主动脉电极可操作为双极电极装置。 第一和第二间隔结构分别将动脉和主动脉电极保持在远离肾动脉和主动脉壁的预定距离处，同时通过双极电极装置输送足以消除邻近肾动脉和主动脉壁的血管周围神经组织的电能。

    OFF-WALL ELECTRODE DEVICE AND METHODS FOR NERVE MODULATION
    10.
    发明申请
    OFF-WALL ELECTRODE DEVICE AND METHODS FOR NERVE MODULATION 审中-公开
    非球面电极装置及神经调制方法

    公开(公告)号：US20130090651A1

    公开(公告)日：2013-04-11

    申请号：US13648987

    申请日：2012-10-10

    申请人： Boston Scientific Scimed, Inc.

    发明人： SCOTT R. SMITH

    IPC分类号： A61B18/14

    CPC分类号： A61B18/1492 ,  A61B2017/32096 ,  A61B2018/00107 ,  A61B2018/00267 ,  A61B2018/00279 ,  A61N1/0558

    摘要： Systems for nerve modulation through the wall of a blood vessel are disclosed. An example system for nerve modulation may include an elongate member extending along a central elongate axis and having a proximal end and a distal end. The elongate member may have a radially expandable member disposed proximate the distal end. A tubular sheath may be cooperatively engaged with the expandable member such that the expandable member is collapsed when in the sheath and can expand when moved distally relative to and past a distal end of the sheath. The expandable member may include a plurality of electrodes and a plurality of spacer struts. Each spacer strut may be configured such that when the self-expanding member is in an expanded state the spacer strut extends out radially further than the electrodes from the central elongate axis.

    摘要翻译： 公开了通过血管壁进行神经调节的系统。 用于神经调节的示例性系统可以包括沿着中心细长轴线延伸并具有近端和远端的细长构件。 细长构件可以具有靠近远端设置的径向可扩张构件。 管状护套可以与可膨胀构件协作地接合，使得可伸缩构件在护套中时折叠，并且当相对于护套远端移动并远离护套的远端时可膨胀。 可膨胀构件可以包括多个电极和多个间隔支柱。 每个间隔支柱可以被配置成使得当自膨胀构件处于膨胀状态时，间隔支柱从中心细长轴线沿径向延伸远离电极。