Abstract:
Various embodiments of the present disclosure describe systems and methods for testing samples (e.g., biological samples, environmental samples, food samples etc.) for microbial contamination. For example, some embodiments describe an adapter assembly with a means to penetrate a septum of a collection vessel and permit gaseous communication between a headspace of the collection vessel and a sensor. In some embodiments, the gases in the headspace of the collection vessel can exit the collection vessel without contaminating the environment outside the system or allowing sample contamination. In some embodiments, the adapter assembly includes a membrane configured to prevent liquid in the collection vessel from contacting the sensor. In some embodiments, the adapter assembly can be used to access media inside the collection vessel for subculturing or aliquotting for another diagnostic process such as molecular diagnostics.
Abstract:
FIG. 1 is a top, right, and front perspective view of an embodiment of a microfluidic cartridge, showing our new design; FIG. 2 is a bottom, right, and front perspective view thereof; FIG. 3 is a front plan view thereof; FIG. 4 is a back plan view thereof; FIG. 5 is a left side plan view thereof; FIG. 6 is a right side plan view thereof; FIG. 7 is a top plan view thereof; FIG. 8 is a bottom plan view thereof; FIG. 9 is an exploded top, right, and front perspective view thereof; FIG. 10 is an exploded bottom, right, and front perspective view thereof; FIG. 11 is a cross-sectional view taken along line 11-11 of FIG. 7; FIG. 12 is a top, right, and front perspective view of a second embodiment of a microfluidic cartridge, showing our new design; FIG. 13 is a bottom, right, and front perspective view thereof; FIG. 14 is a front plan view thereof; FIG. 15 is a back plan view thereof; FIG. 16 is a left side plan view thereof; FIG. 17 is a right side plan view thereof; FIG. 18 is a top plan view thereof; FIG. 19 is a bottom plan view thereof; and, FIG. 20 is a cross-sectional view taken along line 20-20 of FIG. 18. The broken lines illustrate portions of the microfluidic cartridge which form no part of the claimed design.
Abstract:
Embodiments disclosed herein relate to methods and systems for analysis of melting temperatures, and particularly to analysis of duplex nucleic acids.
Abstract:
Provided herein are devices, systems, and methods for measuring the presence of an analyte of interest in a sample. Certain embodiments of the present disclosure are related to culture measurement systems that include a culture vial and a sensor, wherein the sensor is a pH sensor, a responsive label, or an indicator compound, such that the sensor is incorporated into the culture vial for measurement of the pH of the sample.
Abstract:
Embodiments disclosed herein relate to methods and systems for performing an automated assay, and particularly to performing an assay on a plurality of samples on an automated instrument.
Abstract:
Embodiments disclosed herein relate to methods and systems for analysis of melting temperatures, and particularly to analysis of duplex nucleic acids.
Abstract:
Embodiments disclosed herein relate to methods and systems for analysis of melting temperatures, and particularly to analysis of duplex nucleic acids.
Abstract:
Embodiments disclosed herein relate to methods and systems for performing an automated assay, and particularly to performing an assay on a plurality of samples on an automated instrument.
Abstract:
The technology described herein generally relates to microfluidic cartridges. The technology more particularly relates to a single-lane cartridge configured to carry out a single amplification reaction. The reaction chamber has a large volume with a thin-walled shape. A valve can be configured to simultaneously seal a fill channel and a vent channel leading from the reaction chamber.