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    DRUG PRODUCT CONTAINER AND DRUG DELIVERY SYSTEM
    1.
    发明申请
    DRUG PRODUCT CONTAINER AND DRUG DELIVERY SYSTEM 有权

    公开(公告)号：US20220401643A1

    公开(公告)日：2022-12-22

    申请号：US17763692

    申请日：2020-10-14

    申请人： AMGEN INC.

    发明人： Scott R. Gibson ,  Paul D. Faucher ,  Mehran Mojarrad

    IPC分类号： A61M5/148

    摘要： A drug delivery device includes a drug product container, a pressurized vessel, and an urging member. The drug product container can have at least one flexible wall and defining a cavity configured to contain a drug product. The pressurized vessel can contain a gas under pressure. And the urging member is in working connection with the pressurized vessel such that, upon at least partial release of the gas under pressure, the urging member moves from a first portion of the drug product container to a second portion, thereby ejecting at least a portion of the drug product from the drug product container.

    PRESSURE RELIEF VALVE FOR DRUG DELIVERY DEVICE
    2.
    发明申请
    PRESSURE RELIEF VALVE FOR DRUG DELIVERY DEVICE 有权

    公开(公告)号：US20220288305A1

    公开(公告)日：2022-09-15

    申请号：US17626667

    申请日：2020-07-16

    申请人： AMGEN INC.

    发明人： Mehran Mojarrad ,  Ali Nekouzadeh ,  Scott R. Gibson ,  Sheldon Moberg ,  Paul Daniel Faucher

    IPC分类号： A61M5/145 ,  A61M5/142

    摘要： A drug delivery device includes a housing releasably coupled with a patient, a pressure chamber disposed in the housing and including a vent, a container at least partially disposed in the pressure chamber for storing a drug connectable in fluid communication with a fluid conduit, an activation mechanism, and a relief mechanism. The activation mechanism releases a pressurized drive fluid into the pressure chamber for expelling the drug from the container into the fluid conduit. The relief mechanism is operably coupled to the fluid conduit and is adapted to open the vent to release the drive fluid from the pressure chamber in response to a predetermined condition.

    Autoinjector with low energy plunger loading
    4.
    发明授权
    Autoinjector with low energy plunger loading 有权

    公开(公告)号：US11241539B2

    公开(公告)日：2022-02-08

    申请号：US15307501

    申请日：2015-06-26

    申请人： AMGEN INC.

    发明人： Christopher R. Folk ,  Scott R. Gibson ,  Brian J. Intoccia

    IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/31

    摘要： An injection device, method, and system for drug delivery includes a container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug; an injection drive mechanism having a plunger for acting on the stopper and an energy source having a first selected potential energy for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug; and a plunger loading mechanism for substantially preventing the plunger from accelerating to a predetermined velocity before it acts on the stopper. The plunger loading mechanism may be a spring having a second selected potential energy for reducing or eliminating a distance between the plunger and the stopper, prior to the plunger accelerating to the velocity. The second selected potential energy of the spring may be less than the first selected potential energy of the energy source.

    DRUG DELIVERY DEVICE HAVING A NEEDLE GUARD MECHANISM WITH A TUNABLE THRESHOLD OF RESISTANCE TO NEEDLE GUARD MOVEMENT
    5.
    发明申请
    DRUG DELIVERY DEVICE HAVING A NEEDLE GUARD MECHANISM WITH A TUNABLE THRESHOLD OF RESISTANCE TO NEEDLE GUARD MOVEMENT 有权

    公开(公告)号：US20210069416A1

    公开(公告)日：2021-03-11

    申请号：US16951987

    申请日：2020-11-18

    申请人： AMGEN INC.

    发明人： Scott R. Gibson ,  Sheldon Moberg

    IPC分类号： A61M5/20 ,  A61M5/24 ,  A61M5/32

    摘要： A device, method, and system for drug delivery includes a casing for housing a drug storage container, the drug storage container including a dose delivery member, at least a portion of the dose delivery member extending through an opening in the casing; a guard movable relative to the casing between extended and retracted positions, the portion of the dose delivery member being surrounded by the guard in the extended position and the portion of the dose delivery member being at least partially exposed when the guard is in the retracted position; an interference arrangement for providing selected threshold of resistance to movement of the guard from the extended position to the retracted position during insertion of the dose delivery member into body tissue at an injection site, the detent arrangement having a first member associated with a surface within the casing, and a second member extending from the guard, the first and second members engaging one another to retain the guard in the extended position, one of the first and second members moving if the selected threshold of resistance is exceeded to allow the members to slide past one another to allow the guard to move into the retracted position when the device is pressed toward the injection site during insertion of the dose delivery member.

    Autoinjector with shock reducing elements
    6.
    发明授权
    Autoinjector with shock reducing elements 有权

    公开(公告)号：US10722655B2

    公开(公告)日：2020-07-28

    申请号：US15302116

    申请日：2015-05-06

    申请人： AMGEN INC.

    发明人： Christopher Folk ,  Scott R. Gibson

    IPC分类号： A61M5/31 ,  A61M5/315 ,  A61M5/20 ,  F16F9/36 ,  F16F9/32 ,  F16F9/16 ,  F16F9/348 ,  A61M5/32

    摘要： An injection device, method, and system for drug delivery includes a primary container for storing a drug, the container having a stopper movably disposed in the container for expelling the drug, an injection drive mechanism comprising a plunger for acting on the stopper and an energy source for exerting a force on the plunger to cause the plunger to act on the stopper to expel the drug, the force causing the plunger to accelerate to a velocity prior to acting on the stopper, and a damping mechanism for reducing the velocity of the plunger prior to acting on the stopper. The damping mechanism can include a dashpot or an energy absorbing material associated with the plunger. Alternatively or additionally, the damping mechanisms can include absorbing material disposed between support members of an outer casing of the injection device and the primary container.