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    DRUG DELIVERY DEVICE AND SYSTEM
    1.
    发明公开
    DRUG DELIVERY DEVICE AND SYSTEM 审中-公开

    公开(公告)号：US20240091440A1

    公开(公告)日：2024-03-21

    申请号：US17767469

    申请日：2020-10-16

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Mehran Mojarrad ,  Paul D. Faucher ,  Antonio S. Murcia ,  Alan D. Payne ,  Sheldon Moberg ,  Olivia Li

    IPC: A61M5/172 ,  A61M5/142 ,  A61M39/10

    CPC classification number: A61M5/1723 ,  A61M5/14244 ,  A61M39/10 ,  A61M2205/3331

    Abstract: A drug delivery device for delivering a medicament includes a housing, a pump, drive component, an inlet fluid path, an outlet fluid path, an inlet pressure sensor, an outlet pressure sensor, and a controller. The pump is coupled with the housing. The drive component is for driving the pump. The inlet fluid path is configured to deliver medicament to the pump. The outlet fluid path is configured to receive medicament from the pump. The inlet pressure sensor is positioned along the inlet fluid path and configured to measure inlet fluid pressure. The outlet pressure sensor is positioned along the outlet fluid path and configured to measure outlet fluid pressure. The controller is workingly coupled with the inlet pressure sensor, the outlet pressure sensor, and the drive component, wherein the controller is configured to adjust at least one parameter of the drive component based on input information received from the inlet pressure sensor and/or the outlet pressure sensor.

    Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement
    2.
    发明授权
    Drug delivery device having a needle guard mechanism with a turnable threshold of resistance to needle guard movement 有权

    公开(公告)号：US11806509B2

    公开(公告)日：2023-11-07

    申请号：US15540114

    申请日：2016-02-26

    Applicant: AMGEN INC.

    Inventor： Scott R. Gibson ,  Sheldon Moberg

    IPC: A61M5/20 ,  A61M5/24 ,  A61M5/32

    CPC classification number: A61M5/20 ,  A61M5/24 ,  A61M5/3243 ,  A61M5/3202 ,  A61M2005/2013

    Abstract: A drug delivery device includes a casing and a storage container with a dose delivery member, at least a portion of which extends through an opening in the casing. A guard is movable relative to the casing between extended and retracted positions. The guard surrounds the extended portion of the dose delivery member in the extended position, and exposes the extended portion in the retracted position. An interference arrangement is included for providing selected threshold of resistance to movement of the guard from the extended position to the retracted position during insertion of the dose delivery member into body tissue. The arrangement has first and second members engaging one another to retain the guard in the extended position. The first or second member can move if the selected threshold of resistance is exceeded to allow the members to slide and allow the guard to move into the retracted position.

    METHOD OF ASSEMBLING AND FILLING A DRUG DELIVERY DEVICE
    7.
    发明申请
    METHOD OF ASSEMBLING AND FILLING A DRUG DELIVERY DEVICE 审中-公开
    装配和填充药物递送装置的方法

    公开(公告)号：US20160199583A1

    公开(公告)日：2016-07-14

    申请号：US15047815

    申请日：2016-02-19

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Son C. Tran ,  Sheldon Moberg ,  Mark D. Holt

    IPC: A61M5/31 ,  B65B55/10 ,  B65B55/08 ,  B65B3/00 ,  B65B7/28

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有带有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了填充有药物产品的封闭的无菌容器，其包括粒细胞集落刺激因子 （G-CSF）。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

    INJECTOR AND METHOD OF ASSEMBLY
    8.
    发明申请
    INJECTOR AND METHOD OF ASSEMBLY 审中-公开
    注射器和组装方法

    公开(公告)号：US20160199578A1

    公开(公告)日：2016-07-14

    申请号：US15040308

    申请日：2016-02-10

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

    IPC: A61M5/24 ,  A61M5/172

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了充满药物的封闭的无菌容器。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

    INJECTOR AND METHOD OF ASSEMBLY
    9.
    发明申请
    INJECTOR AND METHOD OF ASSEMBLY 审中-公开
    注射器和组装方法

    公开(公告)号：US20160166765A1

    公开(公告)日：2016-06-16

    申请号：US15047792

    申请日：2016-02-19

    Applicant: AMGEN INC.

    Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

    IPC: A61M5/162 ,  A61M5/148 ,  A61M5/158 ,  A61M5/145

    Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

    Abstract translation: 注射器可以包括具有带有内表面的壁和具有内表面的密封组件的容器，壁的内表面和密封组件限定了填充有药物产品的封闭的无菌容器，其包括粒细胞集落刺激因子 （G-CSF）。 注射器还可以包括流体输送系统，该流体输送系统包括清洁的，未被加热的刚性容器针，其具有仅在部分地通过密封组件处于储存状态的点，并且设置成通过密封组件的内表面输送到无菌容器中 州。 此外，注射可以包括适于将容器针从储存状态移动到输送状态的致动器。

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