公开(公告)号：US20200230323A1

公开(公告)日：2020-07-23

申请号：US16839267

申请日：2020-04-03

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  A61M5/162 ,  A61M5/158 ,  A61M5/148 ,  A61M5/145 ,  A61M5/172 ,  A61M5/24 ,  B65B55/10 ,  B65B55/08 ,  B65B7/28 ,  B65B3/00

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US20190298927A1

公开(公告)日：2019-10-03

申请号：US16401471

申请日：2019-05-02

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  B65B55/10 ,  A61M5/162 ,  A61M5/24 ,  A61M5/172 ,  A61M5/145 ,  B65B55/08 ,  B65B7/28 ,  B65B3/00 ,  A61M5/158 ,  A61M5/148

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US20220152308A1

公开(公告)日：2022-05-19

申请号：US17590175

申请日：2022-02-01

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US11298463B2

公开(公告)日：2022-04-12

申请号：US16839267

申请日：2020-04-03

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/31 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158 ,  A61M5/142

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US11129941B2

公开(公告)日：2021-09-28

申请号：US15047815

申请日：2016-02-19

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Son C. Tran ,  Sheldon Moberg ,  Mark D. Holt

IPC: A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158 ,  A61M5/142

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product, including a granulocyte colony-stimulating factor (G-CSF). The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US11273260B2

公开(公告)日：2022-03-15

申请号：US17350883

申请日：2021-06-17

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158 ,  A61M5/142

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US20210308381A1

公开(公告)日：2021-10-07

申请号：US17350883

申请日：2021-06-17

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US10314976B2

公开(公告)日：2019-06-11

申请号：US15040335

申请日：2016-02-10

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/24 ,  A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  A61M5/142 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158 ,  A61M5/162 ,  A61M5/172 ,  B65B55/08 ,  B65B55/10

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US11110225B2

公开(公告)日：2021-09-07

申请号：US15974354

申请日：2018-05-08

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  B65B3/00 ,  B65B7/28 ,  B65B55/08 ,  B65B55/10 ,  A61M5/24 ,  A61M5/162 ,  A61M5/172 ,  A61M5/145 ,  A61M5/148 ,  A61M5/158 ,  A61M5/142

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

公开(公告)号：US20200179609A1

公开(公告)日：2020-06-11

申请号：US16687254

申请日：2019-11-18

Applicant: AMGEN INC.

Inventor： Francisca Tan-Malecki ,  Ronald Forster ,  Scott M. Nunn ,  Mark D. Holt ,  Son C. Tran ,  Sheldon Moberg

IPC: A61M5/31 ,  A61M5/162 ,  A61M5/158 ,  A61M5/148 ,  A61M5/145 ,  A61M5/172 ,  A61M5/24 ,  B65B55/10 ,  B65B55/08 ,  B65B7/28 ,  B65B3/00

Abstract: An injector may include a container having a wall with an interior surface and a seal assembly with an interior surface, the interior surfaces of the wall and the seal assembly defining a closed sterile reservoir filled with a drug product. The injector may also include a fluid delivery system comprising a clean, unsheathed, rigid container needle having a point disposed only partially through the seal assembly in a storage state, and disposed through the interior surface of the seal assembly into the sterile reservoir in a delivery state. Further, the injection may include an actuator that is adapted to move the container needle from the storage state to the delivery state.