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公开(公告)号：US20130029979A1
公开(公告)日：2013-01-31
申请号：US13561662
申请日：2012-07-30
IPC分类号： C07D265/16 , C07D311/04 , A61K31/352 , C07D413/04 , A61P9/06 , C07D405/04 , A61K31/4433 , A61P9/12 , A61P9/04 , A61K31/536 , C07D307/94
CPC分类号： C07D265/16 , C07D311/20 , C07D311/58 , C07D311/96 , C07D405/14 , C07D413/04
摘要： Fused bicyclic compound having an affinity to mineral corticoid receptor (MR), of formula [I]: wherein ring A is benzene having a substituent R1, fused to an adjacent 6-membered heterocyclic ring and further optionally having a substituent(s) other than R1, R1 is alkylsulfonylamino, etc., R2 and R3 are (a) the same of different and are hydrogen, alkyl, or optionally substituted aryl, or (b) combined with each other to form an oxo group or (c) combined with each other at its terminal together with the adjacent carbon atom to form cycloalkyl, X is ═N—, ═C(R4)— or —CH(R4)—, R4 is (a) hydrogen, (b) cyano, (c) halogen, (d) alkyl, (e) alkenyl, (f) cycloalkyl, (g) alkanoyl, (h) carbamoyl, or (i) cycloalkenyl, Ar is an optionally substituted aromatic cyclic group and a dotted line means presence or absence of a double bond, or a pharmaceutically acceptable salt thereof, useful e.g. as an antihypertensive agent.
摘要翻译： 具有式[I]的矿物质类皮质激素受体（MR）的亲和性的稠合双环化合物：其中环A是具有取代基R 1的苯，与相邻的6元杂环稠合，并且进一步任选具有除 R 1，R 1是烷基磺酰基氨基等，R 2和R 3是（a）不同的并且是氢，烷基或任选取代的芳基，或（b）彼此结合形成氧代基或（c）与 X是= N - ， - C（R4） - 或-CH（R4） - ，R4是（a）氢，（b）氰基，（c） 卤素，（d）烷基，（e）烯基，（f）环烷基，（g）烷酰基，（h）氨基甲酰基或（i）环烯基，Ar是任选取代的芳族环状基团，虚线表示存在或不存在 双键或其药学上可接受的盐，例如， 作为抗高血压药。
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公开(公告)号：US07964259B2
公开(公告)日：2011-06-21
申请号：US10545237
申请日：2005-01-26
申请人： Wataru Koshu , Yoichi Takahashi , Michiro Usui , Kazuhiro Sasaki
发明人： Wataru Koshu , Yoichi Takahashi , Michiro Usui , Kazuhiro Sasaki
CPC分类号： G09F3/0292 , Y10T428/14 , Y10T428/1476 , Y10T428/1486 , Y10T428/24802 , Y10T428/28 , Y10T428/2839
摘要： A security label 1 according to the present invention can be removably applied on an image photographing device such as a mobile phone 2 incorporating therein a digital camera to cover a lens part 3 thereof. Upon removal, the security label 1 is bent and makes a trace emerge which shows that the security label 1 has been removed. By applying the security label 1 to the mobile phone 2 to cover the lens part 3 thereof, improper photography can be prevented. In a case where the security label 1 is removed to take a photograph, the trace remains on the security label 1 even if the security label 1 is applied again on the mobile phone 2 to cover the lens part 3 thereof. Thus, the fact that a photograph is improperly taken can be easily understood.
摘要翻译： 根据本发明的安全标签1可以可移除地应用于诸如携带有数字照相机的移动电话2的图像拍摄装置，以覆盖其透镜部分3。 移除后，安全标签1弯曲并发出痕迹，表明安全标签1已被移除。 通过将安全标签1应用于移动电话2以覆盖其透镜部分3，可以防止不正确的拍摄。 在移除安全标签1拍摄照片的情况下，即使在移动电话2上再次使用安全标签1来覆盖其透镜部分3，仍然保留在安全标签1上。 因此，可以容易地理解照片被不正确地摄取的事实。
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公开(公告)号：US20100330665A1
公开(公告)日：2010-12-30
申请号：US12881492
申请日：2010-09-14
IPC分类号： C12M1/26
CPC分类号： B01L3/0268 , B01L3/5085 , B01L2200/12 , B01L2300/069 , B01L2300/10 , B01L2300/1888 , B01L2400/0439 , C12M23/20 , C12M25/06 , C12N5/0068 , C12N2533/12 , C12N2535/10
摘要： A main object of the invention is to provide a new method for producing a cell culture substrate used to cause cells to adhere in a highly precise form onto a base material and then culture the cells.To attain the object, the invention provides a method for producing a cell culture substrate comprising: a patterning substrate forming process of forming, on a base material, a cell culture patterning layer wherein a cell adhesion portion having cell adhesive properties and a cell adhesion-inhibiting portion having cell adhesion-inhibiting properties can be formed by action of a photocatalyst by energy irradiation, thereby forming a patterning substrate; an energy irradiating process of irradiating the energy onto the cell culture patterning layer, thereby forming the cell adhesion portion and the cell adhesion-inhibiting portion in a pattern form by action of the photocatalyst; and a cell-containing liquid applying process of applying a cell-containing liquid onto the cell adhesion portion by a region-selecting applying method of applying the cell-containing liquid selectively onto the patterned cell adhesion portion.
摘要翻译： 本发明的主要目的是提供一种用于生产细胞培养基质的新方法，该方法用于使细胞以高度精确的形式粘附到基材上，然后培养细胞。 为了达到上述目的，本发明提供一种细胞培养基材的制造方法，其特征在于，包括：在基材上形成细胞培养图案形成层的图案形成基板的形成工序，其中，具有细胞粘合性的细胞粘附部， 通过能量照射可以通过光催化剂的作用形成具有细胞粘附抑制特性的抑制部分，从而形成图案化衬底; 将能量照射到细胞培养图案化层上的能量照射方法，由此通过光催化剂的作用形成图案形式的细胞粘附部分和细胞粘附抑制部分; 以及通过选择性地将细胞含有液体施加到图案化细胞粘附部分上的区域选择施加方法将含细胞的液体施加到细胞粘附部分上的含细胞的液体施加方法。
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4.发明授权公开(公告)号：US07528708B2
公开(公告)日：2009-05-05
申请号：US11257651
申请日：2005-10-13
申请人： Akira Saitou , Yoichi Takahashi , Tomotake Ooba , Keiichi Iwazumi , Fujio Higuchi , Keiko Kobayashi
发明人： Akira Saitou , Yoichi Takahashi , Tomotake Ooba , Keiichi Iwazumi , Fujio Higuchi , Keiko Kobayashi
IPC分类号： B60Q1/00
CPC分类号： B60C23/0408
摘要： A variation detection device has a processor, an AD converter converting a signal voltage output from a sensor to generate an AD converted value and outputting the AD converted value to the processor, a temperature sensor detecting a temperature of the sensor, and a memory storing a table which indicates a relationship between temperatures and initial values. When receiving the AD converted value, the processor identifies a temperature of the sensor based on an output of the temperature sensor, reads out an initial value corresponding to the identified temperature from the table, and calculates a variation between the initial value and the AD converted value.
摘要翻译： 变化检测装置具有处理器，AD转换器，其将从传感器输出的信号电压转换成AD转换值，并将AD转换值输出到处理器，温度传感器检测传感器的温度，以及存储器 表示温度和初始值之间的关系。 当接收到AD转换值时，处理器基于温度传感器的输出识别传感器的温度，从表中读出与识别的温度对应的初始值，并计算初始值和AD转换后的变化 值。
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5.发明授权Surface-treated calcium carbonate, method for production thereof and resin composition comprising said calcium carbonate 有权表面处理碳酸钙，其制造方法和包含所述碳酸钙的树脂组合物公开(公告)号：US07341704B2
公开(公告)日：2008-03-11
申请号：US10468156
申请日：2002-11-01
申请人： Hidemitsu Kasahara , Yuusuke Hayashi , Yoichi Takahashi , Seiya Shimizu , Shigeo Takiyama , Katsunori Fukumoto
发明人： Hidemitsu Kasahara , Yuusuke Hayashi , Yoichi Takahashi , Seiya Shimizu , Shigeo Takiyama , Katsunori Fukumoto
IPC分类号： C01B31/24
CPC分类号： B82Y30/00 , C01F11/18 , C01F11/182 , C01P2004/62 , C01P2004/64 , C01P2006/10 , C01P2006/12 , C01P2006/16 , C01P2006/22 , C01P2006/32 , C01P2006/90 , C08K9/04 , C09C1/021
摘要： The surface-treated calcium carbonate is disclosed which is surface-treated with an organic surface treating agent, said surface-treated calcium carbonate satisfies the particular BET specific surface area (Sw), reduced heat amount per unit specific surface area (As), average pore diameter (Dxp) at which an increased amount of mercury penetration reaches the maximum value in a method of mercury penetration, and amount of an average pore diameter [maximum value of an increased amount of mercury penetration (Dyp)/average pore diameter (Dxp)]. The surface-treated calcium carbonate of the present invention is particularly useful for resins and it not only improves adhesion of resin compositions to a subject to be adhered, but forms a rigid coating film when blended into resins.
摘要翻译： 公开了用有机表面处理剂表面处理的表面处理碳酸钙，所述表面处理的碳酸钙满足特定的BET比表面积（Sw），每单位比表面积（As）的减少的热量，平均值 汞渗透方法中汞渗透量增加量达到最大值的孔径（Dxp）和平均孔径（增加的水银渗透量的最大值（Dyp）/平均孔径（Dxp） ）]。 本发明的表面处理碳酸钙对于树脂特别有用，不仅提高了树脂组合物对被粘物的粘附性，而且在树脂中混合时形成刚性涂膜。
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公开(公告)号：US07259707B2
公开(公告)日：2007-08-21
申请号：US11248158
申请日：2005-10-13
申请人： Keiko Kobayashi , Yoichi Takahashi , Tomotake Ooba , Fujio Higuchi , Keiichi Iwazumi , Akira Saitou
发明人： Keiko Kobayashi , Yoichi Takahashi , Tomotake Ooba , Fujio Higuchi , Keiichi Iwazumi , Akira Saitou
IPC分类号： H03M1/12
CPC分类号： B60C23/0433 , G01L9/065
摘要： A semiconductor device includes a reference voltage generating section configured to generate a first reference voltage and a second reference voltage based on a voltage supplied from an external power supply, and an AD (analog/digital) conversion circuit operating based on the first reference voltage to generate an AD conversion signal corresponding to an output signal supplied from an external device. The second reference voltage is supplied to the external device, and a ratio of the first reference voltage and the second reference voltage is kept to a constant value regardless of a temperature of the semiconductor device.
摘要翻译： 一种半导体器件，包括：参考电压产生部，被配置为基于从外部电源提供的电压和基于第一参考电压工作的AD（模拟/数字）转换电路产生第一参考电压和第二参考电压， 产生对应于从外部设备提供的输出信号的AD转换信号。 第二参考电压被提供给外部设备，并且第一参考电压和第二参考电压的比率被保持为恒定值，而与半导体器件的温度无关。
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公开(公告)号：US20060077287A1
公开(公告)日：2006-04-13
申请号：US10545237
申请日：2005-01-26
申请人： Wataru Koshu , Yoichi Takahashi , Michiro Usui , Kazuhiro Sasaki
发明人： Wataru Koshu , Yoichi Takahashi , Michiro Usui , Kazuhiro Sasaki
IPC分类号： H04N5/225
CPC分类号： G09F3/0292 , Y10T428/14 , Y10T428/1476 , Y10T428/1486 , Y10T428/24802 , Y10T428/28 , Y10T428/2839
摘要： A security label 1 according to the present invention can be removably applied on an image photographing device such as a mobile phone 2 incorporating therein a digital camera to cover a lens part 3 thereof. Upon removal, the security label 1 is bent and makes a trace emerge which shows that the security label 1 has been removed. By applying the security label 1 to the mobile phone 2 to cover the lens part 3 thereof, improper photography can be prevented. In a case where the security label 1 is removed to take a photograph, the trace remains on the security label 1 even if the security label 1 is applied again on the mobile phone 2 to cover the lens part 3 thereof. Thus, the fact that a photograph is improperly taken can be easily understood.
摘要翻译： 根据本发明的安全标签1可以可移除地应用于诸如携带有数字照相机的移动电话2的图像拍摄装置，以覆盖其透镜部分3。 移除后，安全标签1弯曲并发出痕迹，表明安全标签1已被移除。 通过将安全标签1应用于移动电话2以覆盖其透镜部分3，可以防止不正确的拍摄。 在移除安全标签1拍摄照片的情况下，即使在移动电话2上再次使用安全标签1来覆盖其透镜部分3，仍然保留在安全标签1上。 因此，可以容易地理解照片被不正确地摄取的事实。
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公开(公告)号：US20060077089A1
公开(公告)日：2006-04-13
申请号：US11246256
申请日：2005-10-11
申请人： Yoichi Takahashi , Tomotake Ooba , Fujio Higuchi , Akira Saitou , Keiichi Iwazumi , Keiko Kobayashi
发明人： Yoichi Takahashi , Tomotake Ooba , Fujio Higuchi , Akira Saitou , Keiichi Iwazumi , Keiko Kobayashi
IPC分类号： H03M1/12
CPC分类号： H03M1/181
摘要： A semiconductor apparatus includes an amplifying unit, a bias controlling unit, an AD converting unit and a controlling unit. The amplifying unit is configured to amplify an input signal to output an amplified signal. The bias controlling unit is configured to generate a bias voltage to be applied to the input signal. The AD converting unit is configured to AD-convert the amplified signal into an output signal. The controlling unit is configured to output a control signal to the bias controlling unit. The controlling unit outputs the control signal when an output value indicated by the output signal is equal to a predetermined value. The bias controlling unit changes the bias voltage in response to the control signal.
摘要翻译： 半导体装置包括放大单元，偏置控制单元，AD转换单元和控制单元。 放大单元被配置为放大输入信号以输出放大的信号。 偏置控制单元被配置为产生要施加到输入信号的偏置电压。 AD转换单元被配置为将放大的信号AD转换为输出信号。 控制单元被配置为向偏置控制单元输出控制信号。 当由输出信号指示的输出值等于预定值时，控制单元输出控制信号。 偏置控制单元响应于控制信号来改变偏置电压。
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公开(公告)号：US20050279730A1
公开(公告)日：2005-12-22
申请号：US11062674
申请日：2005-02-22
CPC分类号： B01L3/0268 , B01L3/5085 , B01L2200/12 , B01L2300/069 , B01L2300/10 , B01L2300/1888 , B01L2400/0439 , C12M23/20 , C12M25/06 , C12N5/0068 , C12N2533/12 , C12N2535/10
摘要： A main object of the invention is to provide a new method for producing a cell culture substrate used to cause cells to adhere in a highly precise form onto a base material and then culture the cells. To attain the object, the invention provides a method for producing a cell culture substrate comprising: a patterning substrate forming process of forming, on a base material, a cell culture patterning layer wherein a cell adhesion portion having cell adhesive properties and a cell adhesion-inhibiting portion having cell adhesion-inhibiting properties can be formed by action of a photocatalyst by energy irradiation, thereby forming a patterning substrate; an energy irradiating process of irradiating the energy onto the cell culture patterning layer, thereby forming the cell adhesion portion and the cell adhesion-inhibiting portion in a pattern form by action of the photocatalyst; and a cell-containing liquid applying process of applying a cell-containing liquid onto the cell adhesion portion by a region-selecting applying method of applying the cell-containing liquid selectively onto the patterned cell adhesion portion.
摘要翻译： 本发明的主要目的是提供一种用于生产细胞培养基质的新方法，该方法用于使细胞以高度精确的形式粘附在基材上，然后培养细胞。 为了达到上述目的，本发明提供一种细胞培养基材的制造方法，其特征在于，包括：在基材上形成细胞培养图案形成层的图案形成基板的形成工序，其中，具有细胞粘合性的细胞粘附部， 通过能量照射可以通过光催化剂的作用形成具有细胞粘附抑制特性的抑制部分，从而形成图案化衬底; 将能量照射到细胞培养图案化层上的能量照射方法，由此通过光催化剂的作用形成图案形式的细胞粘附部分和细胞粘附抑制部分; 以及通过选择性地将细胞含有液体施加到图案化细胞粘附部分上的区域选择施加方法将含细胞的液体施加到细胞粘附部分上的含细胞的液体施加方法。
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公开(公告)号：US06656664B2
公开(公告)日：2003-12-02
申请号：US10255381
申请日：2002-09-26
IPC分类号： G03F100
CPC分类号： H01L27/14812 , H01L27/14643 , H01L27/148
摘要： The method of forming a minute focusing lens with respect to over a photoactive area of an image sensor such as a CCD or CMOS, comprising: coating a resist film on a flattening layer formed over the photoactive area of the image sensor; exposing the resist film to light via a photo-mask, and developing the resist film; and patterning the resist film into a lens configuration provides in this invention in order to form a lens having a designed configuration that provides a good light focusing efficiency. The photo-mask is a light transmission type having no light-shading layer. And, this photo-mask is the one having provided thereon a light transmission portion comprising a light refraction material, having on its surface portion a stairs portion, the stairs portion having the phase of a transmission light at its respective position controlled relative to a prescribed width so that a desired light intensity distribution may be obtained at the surface of the photo-mask light-exposed portion.
摘要翻译： 相对于诸如CCD或CMOS的图像传感器的光活性区域形成微聚焦透镜的方法，包括：在形成在图像传感器的光活性区域上的平坦化层上涂覆抗蚀剂膜; 通过光掩模使抗蚀剂膜曝光，并显影抗蚀剂膜; 并且将抗蚀剂膜图案化成透镜配置在本发明中提供了形成具有提供良好的光聚焦效率的设计构造的透镜。 光掩模是不具有遮光层的透光型。 并且，该光掩模是在其上设置有包含光折射材料的光透射部分的光掩模，其在其表面部分具有楼梯部分，楼梯部分具有在其相应位置处的透射光的相位相对于规定的 宽度，使得可以在光掩模曝光部分的表面处获得期望的光强度分布。
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