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1.发明申请COMPOSITIONS COMPRISING VIRUSES AND METHODS FOR CONCENTRATING VIRUS PREPARATIONS 审中-公开包含病毒的组合物和用于浓缩病毒制备的方法公开(公告)号：US20120093777A1
公开(公告)日：2012-04-19
申请号：US13334403
申请日：2011-12-22
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
IPC: A61K35/76
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，其包含缓冲的多羟基烃的制剂中的病毒，以在约2℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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公开(公告)号：US20080261289A1
公开(公告)日：2008-10-23
申请号：US12147391
申请日：2008-06-26
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellkamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellkamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
IPC: C12N7/00
CPC classification number: C12N15/86 , C12N7/00 , C12N2710/10343 , C12N2710/10351
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
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3.发明申请Compositions Comprising Viruses and Methods for Concentrating Virus Preparations 审中-公开包含病毒和病毒制备浓缩方法的组合物公开(公告)号：US20080138318A1
公开(公告)日：2008-06-12
申请号：US11932302
申请日：2007-10-31
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
IPC: A61K35/76
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 20° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，该组合物包含缓冲的多羟基烃的制剂中的病毒，以在约20℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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4.发明申请Particulate-stabilized injectable pharmacutical compositions of posaconazole 审中-公开泊沙康唑的颗粒稳定的可注射药物组合物公开(公告)号：US20090226527A1
公开(公告)日：2009-09-10
申请号：US12380790
申请日：2009-03-03
Applicant: Leonore Witchey-Lakshmanan , Sydney Ugwu , Varda E. Sandweiss , Catherine Hardalo , Roberta S. Hare , Gopal Krishna , Zaiqi Wang , Marco Taglietti
Inventor： Leonore Witchey-Lakshmanan , Sydney Ugwu , Varda E. Sandweiss , Catherine Hardalo , Roberta S. Hare , Gopal Krishna , Zaiqi Wang , Marco Taglietti
CPC classification number: A61K31/496 , A61K9/0019 , A61K31/137 , A61K31/513 , A61K31/7048 , A61K45/06 , A61K47/24 , A61K47/26 , Y02A50/409 , Y02A50/414 , A61K2300/00
Abstract: The present invention provides formulations useful for treating infections, in particular, formulations that include the active pharmaceutical ingredient Posaconazole in an injectable suspension of particles that is stable when subjected to terminal sterilization. Preferred median particle sizes of between 1.5 and 3.0 microns are found to result in superior pharmacokinetic characteristics-displayed in FIG. 7.
Abstract translation: 本发明提供了可用于治疗感染的制剂，特别是包含活性药物成分泊沙康唑在经受终末灭菌时稳定的颗粒的可注射悬浮液中的制剂。 发现1.5至3.0微米的优选中值粒度导致优异的药代动力学特征 - 显示在图1中。 7。
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5.发明申请Compositions comprising viruses and methods for concentrating virus preparations 审中-公开包含病毒的组合物和用于浓缩病毒制剂的方法公开(公告)号：US20090098632A1
公开(公告)日：2009-04-16
申请号：US12080653
申请日：2008-04-04
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
IPC: C12N7/00
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，其包含缓冲的多羟基烃的制剂中的病毒，以在约2℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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Patent Agency Ranking
6.发明申请Compositions comprising viruses and methods for concentrating virus preparations 审中-公开包含病毒的组合物和用于浓缩病毒制剂的方法公开(公告)号：US20080194002A1
公开(公告)日：2008-08-14
申请号：US12082853
申请日：2008-04-14
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc , Frederick William Porter , John Chu-Tay Tang , Peter Ihnat
IPC: C12N7/02
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，其包含缓冲的多羟基烃的制剂中的病毒，以在约2℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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公开(公告)号：US4489070A
公开(公告)日：1984-12-18
申请号：US550434
申请日：1983-11-10
Applicant: Varda E. Sandweiss , Elliot Stupak , Paul H. Shapiro
Inventor： Varda E. Sandweiss , Elliot Stupak , Paul H. Shapiro
CPC classification number: A61K47/02 , A61K31/57 , A61K47/32 , A61K9/0014
Abstract: Disclosed is an elegant formulation of betamethasone dipropionate useful as a topical anti-inflammatory product.
Abstract translation: 公开了用作局部抗炎产品的二丙酸倍他米松的优雅配方。
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8.发明申请COMPOSITIONS COMPRISING VIRUSES AND METHODS FOR CONCENTRATING VIRUS PREPARATIONS 审中-公开包含病毒的组合物和用于浓缩病毒制备的方法公开(公告)号：US20080293123A1
公开(公告)日：2008-11-27
申请号：US12188067
申请日：2008-08-07
Applicant: Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
Inventor： Andreas Frei , Henry K.H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Laureano L. Bondoc, JR. , Frederick William Porter, IV , John Chu-Tay Tang , Peter Ihnat
IPC: C12N7/02
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，其包含缓冲的多羟基烃的制剂中的病毒，以在约2℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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9.发明授权Compostions comprising viruses and methods for concentrating virus preparations 有权包含病毒的组合物和用于浓缩病毒制剂的方法公开(公告)号：US06544769B1
公开(公告)日：2003-04-08
申请号：US09249646
申请日：1999-02-12
Applicant: Andreas Frei , Henry K. H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Peter Ihnat
Inventor： Andreas Frei , Henry K. H. Kwan , Varda E. Sandweiss , Gary J. Vellekamp , Pui-Ho Yuen , Peter Ihnat
IPC: C12N700
CPC classification number: C12N7/00 , A61K39/12 , A61K39/235 , A61K48/0091 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/10351 , Y10S514/937
Abstract: A composition is disclosed comprising virus in a formulation comprising a polyhydroxy hydrocarbon buffered to maintain a pH in a range from about 7 to about 8.5 at a temperature in the range from about 2° C. to 27° C. Methods for concentrating and purifying virus preparations are also disclosed.
Abstract translation: 公开了一种组合物，其包含缓冲的多羟基烃的制剂中的病毒，以在约2℃至27℃的温度范围内将pH保持在约7至约8.5的范围内。浓缩和纯化病毒的方法 准备工作也被披露。
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公开(公告)号：US4482539A
公开(公告)日：1984-11-13
申请号：US494214
申请日：1983-05-13
Applicant: Varda E. Sandweiss , Elliot Stupak , Paul H. Shapiro
Inventor： Varda E. Sandweiss , Elliot Stupak , Paul H. Shapiro
CPC classification number: A61K31/57 , A61K47/02 , A61K47/32 , A61K9/0014 , Y10S514/887
Abstract: Disclosed is an elegant cream-like formulation of betamethasone dipropionate useful as a topical antiinflammatory product.
Abstract translation: 公开了用作局部抗炎产品的优质乳膏状二丙酸倍他米松配方。
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