Invention Application
US20090226527A1 Particulate-stabilized injectable pharmacutical compositions of posaconazole
审中-公开
泊沙康唑的颗粒稳定的可注射药物组合物
- Patent Title: Particulate-stabilized injectable pharmacutical compositions of posaconazole
- Patent Title (中): 泊沙康唑的颗粒稳定的可注射药物组合物
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Application No.: US12380790Application Date: 2009-03-03
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Publication No.: US20090226527A1Publication Date: 2009-09-10
- Inventor: Leonore Witchey-Lakshmanan , Sydney Ugwu , Varda E. Sandweiss , Catherine Hardalo , Roberta S. Hare , Gopal Krishna , Zaiqi Wang , Marco Taglietti
- Applicant: Leonore Witchey-Lakshmanan , Sydney Ugwu , Varda E. Sandweiss , Catherine Hardalo , Roberta S. Hare , Gopal Krishna , Zaiqi Wang , Marco Taglietti
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61P31/10
Abstract:
The present invention provides formulations useful for treating infections, in particular, formulations that include the active pharmaceutical ingredient Posaconazole in an injectable suspension of particles that is stable when subjected to terminal sterilization. Preferred median particle sizes of between 1.5 and 3.0 microns are found to result in superior pharmacokinetic characteristics-displayed in FIG. 7.
Information query
