Pharmaceutical formulation for administering paracetamol by buccal/gingival route

    公开(公告)号:US11617730B2

    公开(公告)日:2023-04-04

    申请号:US16489378

    申请日:2018-02-28

    发明人: Eric Goupil

    摘要: The present invention concerns a pharmaceutical formulation for administering paracetamol by buccal/gingival route consisting of a hydroalcoholic solution comprising dissolved paracetamol, characterised in that: #the mass of paracetamol is between 95 mg and 190 mg, #the volume of said hydroalcoholic solution is between 1.0 ml and 2.0 ml, #the degree of alcohol of said hydroalcoholic solution is between 48.5° and 52.5°, and #the concentration of paracetamol in said hydroalcoholic solution is between 85 mg/ml and 110 mg/ml. The present invention also concerns said pharmaceutical formulation for the use of same for accelerating the speed at which paracetamol passes through the blood-brain barrier, and the use thereof as a drug, in particular for the symptomatic treatment of pain or fever.

    DEVICE FOR PREPARING A DOSE OF MEDICAMENT ON DEMAND

    公开(公告)号:US20210008293A1

    公开(公告)日:2021-01-14

    申请号:US16979399

    申请日:2019-03-11

    发明人: Marc Maury

    IPC分类号: A61M5/315 A61M5/24

    摘要: The invention concerns a device for preparing a dose of medicament on demand, comprising at least one receptacle (10), at least one cartridge (12) of a medicinal composition intended to enter said at least one receptacle, the medicinal composition being in liquid or solid powder form, as well as dosing means (14) for dosing said medicinal composition, monitoring means (16) for monitoring the dose of the medicinal composition delivered and control means (18) for controlling the at least one cartridge (12), the dosing means (14) and the monitoring means (16).